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Bacille Calmette Guerin (BCG) vaccination can protect children from tuberculosis infection as well as active TB disease

There are about 10 million cases of TB globally each year and 1 in 3 people are infected with the TB bacterium. BCG is the most widely used vaccine worldwide, but its mechanism of protection is poorly understood. It is thought to prevent progression of infection to active TB but whether it protects against the acquisition of infection itself has not been investigated in humans.

13 Oct 2005

Whooping cough vaccine 90 percent effective

A vaccine to protect adults and adolescents against illness due to Bordetella pertussis infection--or whooping cough--has proved more than 90 percent effective in a national, large-scale clinical study, according to research results published in this week's issue of The New England Journal of Medicine.

12 Oct 2005

Why breast black cancer patients experience lower survival rates than other women

Black women with stage I or II breast cancer are more likely than their counterparts of other races to abandon chemotherapy before completing their full course of treatment, according to a recent Columbia University Medical Center study.

12 Oct 2005

Protein called CPSF73 performs a necessary step in the production of human chromosomes

The study found that a protein called CPSF73 acts like scissors to cut strands of histone messenger RNA (mRNA) in the cell nucleus. This cutting action produces the mRNA needed to create histone proteins that combine with DNA to form chromosomes.

12 Oct 2005

Lowering infant's body temperature within the first six hours of life reduces the chances for disability

Lowering an infant's body temperature to about 92 degrees Fahrenheit within the first six hours of life reduces the chances for disability and death among infants who failed to receive enough oxygen or blood to the brain during birth. The research study findings appear in tomorrow's 2005 New England Journal of Medicine.

12 Oct 2005

Study on childhood asthma shows home-based interventions are cost-effective

New data suggest that a home-based environmental intervention program is a cost-effective way to improve the health of inner-city children who have moderate to severe asthma.

12 Oct 2005

New study of the public's priorities for the funding of research into what people eat and how it affects their health

The study, conducted by MORI Social Research Institute, explores any differences between the agendas of the public and research funders at a time when the health implications of the food that we consume have a very high profile. The study was commissioned by the Biotechnology and Biological Sciences Research Council (BBSRC) and the Institute of Food Research (IFR), who will consider the results as part of their strategic planning for future funding.

12 Oct 2005

$Older men with Parkinson's disease at increased risk of bone fractures$

Older men with Parkinson's disease at increased risk of bone fractures

Researchers found that Parkinson’s disease (PD) in older men is associated with lower bone mineral density and suggested that physicians should consider screening older male patients with PD for osteoporosis.

12 Oct 2005

Psychological stress during infancy has been found to cause early impaired memory

The study suggests that the emotional stress associated with parental loss, abuse or neglect may contribute to the type of memory loss during middle-age years that is normally seen in the elderly.

11 Oct 2005

Incidence of end-stage renal disease is lower than previously estimated

Diabetic kidney disease is one of the most severe complications of type 1 diabetes, and diabetes is the most important cause of end-stage renal disease (ESRD; severely impaired kidney function, requiring dialysis) in industrialized countries, according to background information in the article. Data on patients' risk of developing ESRD are sparse.

11 Oct 2005

Study confirms that couples using natural family planning have intercourse just as frequently as couples using other methods

Couples who use fertility awareness-based methods of family planning have sex just as often as couples who use other contraceptive methods -- they just time it differently, according to a new Georgetown University Institute for Reproductive Health study to be published in a forthcoming edition of the Journal of Biosocial Science.

11 Oct 2005

New Orleans floodwaters not as toxic as previously thought

The floodwaters that inundated New Orleans immediately following Hurricane Katrina were similar in content to the city’s normal storm water and were not as toxic as previously thought, according to a study by researchers at Louisiana State University.

11 Oct 2005

Sleletal muscle findings highlight the importance of exercise in obese people

The findings suggest that muscle bears a metabolic memory of obesity, which may help to explain why sustained weight loss can be difficult despite cutting calories, according to the researchers. Exercise might more successfully override the aberrant metabolic program in muscle, they suggest, thereby improving the long-term prognosis of those prone to obesity.

11 Oct 2005

Newly discovered hormone plays an important role in the digestion of fat, cholesterol, and fat-soluble vitamins

A newly discovered hormone plays an important role in the digestion of fat, cholesterol, and fat-soluble vitamins, such as vitamins A, E, and D, according to a new study in the October 2005 issue of Cell Metabolism.

11 Oct 2005

Experimental HIV vaccine progresses in trials

A novel vaccine targeted to multiple HIV subtypes found worldwide has moved into the second phase of clinical testing, the National Institute of Allergy and Infectious Diseases (NIAID) announced today.

11 Oct 2005

Very low LDL cholesterol levels appear to be safe for heart patients on statin therapies

"There was no apparent safety concern for patients whose resultant LDL on intensive therapy was lower than current guidelines. There was a trend toward improved clinical outcomes in the lowest LDL groups," said Stephen D. Wiviott, M.D., from Brigham and Women's Hospital in Boston, Massachusetts.

11 Oct 2005

Real-world treatment of patients with acute coronary syndromes

A review of more than 56,000 cases of acute coronary syndromes reveals that older patients are less likely to receive treatment recommended by guidelines, even though they benefit as much or more than younger patients when the recommended treatment is provided, according to a new study in the Oct. 18, 2005, issue of the Journal of the American College of Cardiology.

11 Oct 2005

Disparities in breast cancer survival between blacks and whites remain

Black breast cancer patients have shorter survival than white breast cancer patients largely because of a higher rate of other disorders, such as diabetes and hypertension, according to a study in the October 12 issue of JAMA: The Journal of the American Medical Association.

11 Oct 2005

Paying clinicians to reach a common, fixed performance target may produce little gain in overall quality

...and may largely reward those with higher performance at baseline, according to a study in the October 12 issue of JAMA: The Journal of the American Medical Association.

11 Oct 2005

Defibrillator implantations performed by physicians with low volume are more likely to have adverse outcomes

As the implantation of cardioverter-defibrillator devices to prevent sudden cardiac death becomes increasingly popular, patients are likely to get the best results when they are treated by physicians who perform the procedures frequently, according to a new study in the Oct. 18, 2005, issue of the Journal of the American College of Cardiology.

11 Oct 2005

Drug Trial News

Bacille Calmette Guerin (BCG) vaccination can protect children from tuberculosis infection as well as active TB disease

Whooping cough vaccine 90 percent effective

Why breast black cancer patients experience lower survival rates than other women

Protein called CPSF73 performs a necessary step in the production of human chromosomes

Lowering infant's body temperature within the first six hours of life reduces the chances for disability

Study on childhood asthma shows home-based interventions are cost-effective

New study of the public's priorities for the funding of research into what people eat and how it affects their health

Older men with Parkinson's disease at increased risk of bone fractures

Psychological stress during infancy has been found to cause early impaired memory

Incidence of end-stage renal disease is lower than previously estimated

Study confirms that couples using natural family planning have intercourse just as frequently as couples using other methods

New Orleans floodwaters not as toxic as previously thought

Sleletal muscle findings highlight the importance of exercise in obese people

Newly discovered hormone plays an important role in the digestion of fat, cholesterol, and fat-soluble vitamins

Experimental HIV vaccine progresses in trials

Very low LDL cholesterol levels appear to be safe for heart patients on statin therapies

Real-world treatment of patients with acute coronary syndromes

Disparities in breast cancer survival between blacks and whites remain

Paying clinicians to reach a common, fixed performance target may produce little gain in overall quality

Defibrillator implantations performed by physicians with low volume are more likely to have adverse outcomes

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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