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More effective flu vaccine begins clinical trials across the U.S.

A more effective seasonal flu vaccine is about to be tested in clinical trials across the US.

1 Jul 2019

Large prevention trial launched for people exposed to multidrug-resistant tuberculosis

A large clinical trial to assess treatments for preventing people at high risk from developing multidrug-resistant tuberculosis has begun.

25 Jun 2019

Investigational drug for treatment of sickle cell disease shows early promise in clinical trials

An investigational drug for the treatment of sickle cell disease is showing early promise in clinical trials for impacting biomarkers of the disease in patients, reported UConn School of Medicine researchers at the European Hematology Association Congress in Amsterdam this week.

20 Jun 2019

Revolutionary cancer drugs that target any tumor to be fast-tracked into hospitals by NHS

Patients in England could be some of the first in the world to be treated with revolutionary cancer drugs that can target any type of tumor.

19 Jun 2019

Groundbreaking drug boosts growth rates in children with achondroplasia

A groundbreaking drug that helps regulate bone development has boosted growth rates in children with achondroplasia - the most common type of dwarfism - in a global trial led by Melbourne's Murdoch Children's Research Institute.

18 Jun 2019

Researchers investigate why many cancer clinical trials fail to enroll enough patients

The increasing sophistication of cancer treatments threatens to outpace the ability of health care providers to enroll patients in clinical trials to test those therapies. That's a key finding by researchers in UT Southwestern's new Department of Population and Data Sciences.

18 Jun 2019

Topical cream found to be effective in reversing the effects of vitiligo

A nationwide phase II clinical trial, coordinated out of Tufts Medical Center in Boston, has found that a topical cream was extremely effective in reversing the effects of vitiligo, a relatively common autoimmune disease that causes loss of skin pigmentation.

17 Jun 2019

New study finds almost 400 established medical practices that don’t work

A new study set out to explore what does and does not work in the field of modern medical practice, and came up with 396 reported reversals of previously accepted medical practice over the last few decades.

12 Jun 2019

Drug that targets the immune system can delay type 1 diabetes in high risk children, adults

A drug that targets the immune system can delay the onset of type 1 diabetes an average of two years in children and adults at high risk, according to findings from TrialNet's Teplizumab (anti-CD3) Prevention Study published in the New England Journal of Medicine.

10 Jun 2019

Myeloma UK launches new research program to support patient-centric myeloma clinical trials

Myeloma UK is launching a new research program to continue support for patient-centric myeloma clinical trials in the UK, the UK Myeloma Research Alliance-Myeloma UK-Concept and Access Research Programme.

10 Jun 2019

New immunosuppressive regimens may improve outcomes for kidney transplant patients

Preliminary results from a $5.2 million clinical trial led by University of Cincinnati researchers show that the immunosuppressive drug belatacept can help safely and effectively treat kidney transplant patients without the negative long-term side effects of traditional immunosuppressive regimens, the study's leaders announced this week.

6 Jun 2019

Alzheimer's therapy may be effective in treating individuals addicted to opioids

Clinical trial results reveal that a medication used to treat Alzheimer's disease may also be an effective therapy for individuals addicted to opioids. The findings are published in The American Journal on Addictions.

6 Jun 2019

Combination immunotherapy shows promise in pre-surgical setting for early-stage lung cancers

Neoadjuvant, or pre-surgical, treatment with nivolumab plus ipilimumab resulted in an overall major pathologic response rate of 33 percent of treated patients with early-stage, resectable non-small cell lung cancers, meaning these patients had less than or equal to 10 percent viable tumor remaining at surgery.

3 Jun 2019

Georgetown University Medical Center announces launch of clinical trial for Lewy body dementia

Georgetown University Medical Center announces the launch of the only known therapeutic (disease modifying) clinical trial for Lewy body dementia, a neurological disorder that affects a million people in the United States for which there are no approved medications that modify the disease.

3 Jun 2019

International clinical study of new drug to treat advanced prostate cancers yields promising results

Today the New England Journal of Medicine published the first results of a phase III international clinical study called TITAN (National Clinical Trials Number 02489318), which evaluated the effectiveness and safety of a new drug, apalutamide, to treat advanced prostate cancers.

3 Jun 2019

Targeted therapy plus hormone therapy improves survival in premenopausal patients with advanced HR+ breast cancer

Adding the targeted therapy ribociclib to hormone therapy significantly improved overall survival (OS) in premenopausal patients with advanced hormone receptor-positive (HR+) breast cancer, according to results of the MONALEESA-7 Phase III clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.

3 Jun 2019

Oral androgen receptor inhibitor improves outcomes for men with mHSPC

Enzalutamide, an oral androgen receptor inhibitor, can improve outcomes for men with metastatic hormone-sensitive prostate cancer, according to a large study presented by Christopher Sweeney, MBBS of Dana-Farber Cancer Institute's Lank Center for Genitourinary Oncology, during the American Society of Clinical Oncology Annual Meeting.

3 Jun 2019

Drug therapy may delay onset of myeloma symptoms, finds study

The largest randomized trial involving smoldering multiple myeloma suggests that lenalidomide, a cancer drug, may delay the onset of myeloma symptoms, according to Mayo Clinic researchers.

3 Jun 2019

Pre-surgical neoadjuvant treatment shows promise in trial for patients with operable NSCLC

For patients with operable non-small cell lung cancer, pre-surgical "neoadjuvant" treatment with an immune checkpoint inhibitor was well tolerated and, in many cases, caused significant tumor cell death in a large, multicenter clinical trial involving investigators at Dana-Farber Cancer Institute, Brigham and Women's Hospital, and nine other research centers

31 May 2019

Combination treatment effective as front-line therapy for select chronic lymphocytic leukemia patients

Ibrutinib and venetoclax, two FDA-approved drugs for treating chronic lymphocytic leukemia, have been shown to be effective when given together for high-risk and older patients with the disease, according to a study at The University of Texas MD Anderson Cancer Center.

30 May 2019

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Drug Trial News

More effective flu vaccine begins clinical trials across the U.S.

Large prevention trial launched for people exposed to multidrug-resistant tuberculosis

Investigational drug for treatment of sickle cell disease shows early promise in clinical trials

Revolutionary cancer drugs that target any tumor to be fast-tracked into hospitals by NHS

Groundbreaking drug boosts growth rates in children with achondroplasia

Researchers investigate why many cancer clinical trials fail to enroll enough patients

Topical cream found to be effective in reversing the effects of vitiligo

New study finds almost 400 established medical practices that don’t work

Drug that targets the immune system can delay type 1 diabetes in high risk children, adults

Myeloma UK launches new research program to support patient-centric myeloma clinical trials

New immunosuppressive regimens may improve outcomes for kidney transplant patients

Alzheimer's therapy may be effective in treating individuals addicted to opioids

Combination immunotherapy shows promise in pre-surgical setting for early-stage lung cancers

Georgetown University Medical Center announces launch of clinical trial for Lewy body dementia

International clinical study of new drug to treat advanced prostate cancers yields promising results

Targeted therapy plus hormone therapy improves survival in premenopausal patients with advanced HR+ breast cancer

Oral androgen receptor inhibitor improves outcomes for men with mHSPC

Drug therapy may delay onset of myeloma symptoms, finds study

Pre-surgical neoadjuvant treatment shows promise in trial for patients with operable NSCLC

Combination treatment effective as front-line therapy for select chronic lymphocytic leukemia patients

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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