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Study dispels the hypothesis that metformin could help exercising seniors gain more muscle mass

A clinical trial initiated by University of Kentucky researchers argues against the hypothesis that the diabetes drug metformin could help exercising seniors gain more muscle mass. The double-blind trial, conducted at the University of Kentucky and University of Alabama at Birmingham, found that older adults who took metformin while performing rigorous resistance exercise training had smaller gains in muscle mass than the placebo group.

22 Oct 2019

Beta-blockers do not reduce risk of COPD exacerbations

New research from scientists at the University of Alabama at Birmingham published in the New England Journal of Medicine has found that beta-blockers used in a clinical trial for patients with chronic obstructive pulmonary disease do not reduce the risk of flare-ups of the disease, also called COPD exacerbations.

21 Oct 2019

University Of Minnesota opens clinical trial of first-of-its-kind NK cell cancer immunotherapy

A new cancer clinical trial has opened at the M Health Fairview University of Minnesota Medical Center that leverages the groundbreaking research on stem cells and natural killer cells done at the Masonic Cancer Center and applies it to attack acute myeloid leukemia and B-cell lymphoma.

21 Oct 2019

Vitamin D oral sprays equally effective as taking a tablet

Taking vitamin D by oral spray is just as effective as taking a tablet, research from the University of Sheffield has found.

15 Oct 2019

Widely available drug could reduce deaths in traumatic brain injury patients, major study shows

A low cost and widely available drug could reduce deaths in traumatic brain injury patients by as much as 20%, depending on the severity of injury, according to a major study published in The Lancet.

15 Oct 2019

Novel clinical trial to examine use of cannabidiol in people with Parkinson's-related psychosis

A pioneering clinical trial will investigate the use of cannabidiol (CBD) - a compound found in the cannabis plant - in people with Parkinson's-related psychosis.

14 Oct 2019

Antibody-based eye drop treatment reduces signs and symptoms of dry eye disease

Researchers at the University of Illinois at Chicago are the first to identify the presence of a specific type of antibody, called anti-citrullinated protein autoantibodies, or ACPAs, in human tear fluid.

11 Oct 2019

Combination drug appears to improve lung health in patients with cystic fibrosis, but with caveats

In adolescent and adult patients with cystic fibrosis taking lumacaftor-ivacaftor (ORKAMBI), the combination drug appears to improve lung function and body weight and reduce the need for intravenous antibiotic treatment, according to a French study published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

11 Oct 2019

Dupilumab provides clinical benefit to adolescents with moderate-to-severe atopic dermatitis

Results from a phase IIa open-label trial and a subsequent phase III open-label extension trial reinforce findings from an earlier short-term trial that adolescents with moderate-to-severe atopic dermatitis, or eczema, can experience significant improvements with dupilumab.

9 Oct 2019

New drug Aliskiren shows promise for heart failure patients

A study published in the International Journal of Molecular Sciences, as part of a special issue “Heart Failure: From Molecular Basis to Therapy”, in August 2019, shows that aliskiren, a drug approved by the US Food and Drug Administration (FDA), can improve survival for over 5 years, on average, and enhance life quality in patients who have been correctly diagnosed with heart failure.

9 Oct 2019

GUMC now offers three clinical trials to study treatments for LBD

Georgetown University Medical Center, a Lewy Body Dementia (LBD) Association Research Center of Excellence, is now offering three clinical trials to study new treatments for LBD, a disease often confused with Parkinson's and Alzheimer's disease.

8 Oct 2019

UTHealth: Psychedelic drug being studied to relieve treatment-resistant depression

Psilocybin, a psychedelic drug believed to help rewire the brain, is now being studied to relieve treatment-resistant depression at The University of Texas Health Science Center at Houston (UTHealth) as part of a global Phase II clinical trial.

8 Oct 2019

New experimental growth factor drug appears to prevent worsening of osteoarthritis

More than 10 percent of Americans over age 60 experience knee pain related to osteoarthritis, the most common disease of the knee joint. Osteoarthritis of the knee causes pain, activity limitation, physical disability, reduced health-related quality of life and excess mortality compared with the general population.

8 Oct 2019

Phage engineering gives antibacterial therapy a new lease of life

Researchers have been identifying and modifying known phages to fight against infectious bacteria.

4 Oct 2019

Study shows how opt-out organ donation could affect transplant waiting lists in the U.S.

Every year in the United States, about 7,500 people die while waiting for an organ transplant, and that number is expected to increase in coming years as demographics shift.

3 Oct 2019

New study shows response to HIV vaccine in 6 weeks

A US study on DNA-based and protein HIV vaccines has shown that an antibody and cellular immune response occurs within six weeks.

2 Oct 2019

New study shows response to HIV vaccine in 6 weeks

A new study using DNA-based and protein HIV vaccines in various combinations shows that antibody and cellular immune response occurs within 6 weeks from the date of vaccination, and the combination must be administered together for the most rapid protection. This will enable more large-scale testing of the vaccine for effectiveness. About 40 million people today have HIV infections, and 1.2 million deaths a year are related to this infection.

1 Oct 2019

Triple-drug combo inhaler for asthmatics with poor symptom control

New research shows that asthmatics who have poor symptom control could be benefited by using a three-drug combination inhaler. The standard treatment for these patients is a two-drug combination of an inhaled corticosteroid (ICS) and a long acting beta 2 agonist (LABA). The third ingredient added to the mix is a long acting muscarinic antagonist, add the researchers. This combination successfully improved lung function and reduced exacerbations of asthma wrote the researchers.

1 Oct 2019

Cannabis: CBD vs THC causes lower psychiatric side-effects

A study has revealed how cannabidiol works against tetrahydrocannabinol to prevent psychiatric side effects.

1 Oct 2019

Modern chemo more effective than second targeted hormone therapy against resistant prostate cancer

A modern chemotherapy drug is more effective for men with advanced prostate cancer than a second targeted hormone therapy in patients who have stopped responding to treatment, a major clinical trial shows.

30 Sep 2019

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Drug Trial News

Study dispels the hypothesis that metformin could help exercising seniors gain more muscle mass

Beta-blockers do not reduce risk of COPD exacerbations

University Of Minnesota opens clinical trial of first-of-its-kind NK cell cancer immunotherapy

Vitamin D oral sprays equally effective as taking a tablet

Widely available drug could reduce deaths in traumatic brain injury patients, major study shows

Novel clinical trial to examine use of cannabidiol in people with Parkinson's-related psychosis

Antibody-based eye drop treatment reduces signs and symptoms of dry eye disease

Combination drug appears to improve lung health in patients with cystic fibrosis, but with caveats

Dupilumab provides clinical benefit to adolescents with moderate-to-severe atopic dermatitis

New drug Aliskiren shows promise for heart failure patients

GUMC now offers three clinical trials to study treatments for LBD

UTHealth: Psychedelic drug being studied to relieve treatment-resistant depression

New experimental growth factor drug appears to prevent worsening of osteoarthritis

Phage engineering gives antibacterial therapy a new lease of life

Study shows how opt-out organ donation could affect transplant waiting lists in the U.S.

New study shows response to HIV vaccine in 6 weeks

New study shows response to HIV vaccine in 6 weeks

Triple-drug combo inhaler for asthmatics with poor symptom control

Cannabis: CBD vs THC causes lower psychiatric side-effects

Modern chemo more effective than second targeted hormone therapy against resistant prostate cancer

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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