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New combination therapy found to be well tolerated in patients with aggressive brain tumor

A phase I clinical trial that set out to assess the safety of a new combination therapy for a type of aggressive brain tumour has found the treatment to be well tolerated in patients.

30 Mar 2019

Clinical trial examines medicinal cannabis as potential treatment for severe Tourette syndrome

A pioneering clinical trial investigating medicinal cannabis as a potential treatment for people living with severe Tourette syndrome will be conducted by Wesley Medical Research, in Brisbane in Australia, with cannabis supply facilitated by Lambert Initiative for Cannabinoid Therapeutics at University of Sydney.

28 Mar 2019

NIH starts clinical trial of drug to treat cravings associated with opioid use disorder

A clinical trial of an experimental drug designed to treat cravings associated with opioid use disorder has begun in the National Institutes of Health Clinical Center.

22 Mar 2019

New combination treatment shows promise for common brain tumor in children

A new combination treatment aimed at resistant and recurrent low-grade gliomas slowed tumor growth and killed tumor cells in laboratory and mouse models.

22 Mar 2019

New Australian drug trial achieves remarkable results in patients with acute myeloid leukemia

The prognosis for older patients with acute myeloid leukemia is poor: very few achieve remission and for those that don't the option is largely palliative.

21 Mar 2019

Researchers report promising results of potential reversal agent

In patients with acute coronary syndromes, coronary artery stenting, or a history of prior heart attacks, antiplatelet therapy can be lifesaving.

18 Mar 2019

Novel drug shows potential to prevent sepsis progression

Research into a new breakthrough therapy in the fight against sepsis has shown that the drug has potential to stop all sepsis-causing bacteria from triggering organ damage in the early stages of the condition.

8 Mar 2019

Study examines effect of herbal medicine product on bedwetting in children

A new clinical trial investigating whether an herbal medicine product can benefit school-age children experiencing bedwetting is being led by a collaboration between researchers from the Australian Research Centre in Complementary and Integrative Medicine at the University of Technology Sydney and the Office of Research at Endeavour College of Natural Health.

5 Mar 2019

Experimental treatment offers hope to restore cells damaged in Parkinson's disease

A pioneering clinical trials program that delivered an experimental treatment directly to the brain offers hope that it may be possible to restore the cells damaged in Parkinson's disease.

27 Feb 2019

Pioneering trial offers hope for patients with Parkinson’s disease

In a pioneering new clinical trial, researchers have succeeded in delivering a cell-restoring drug directly to the brains of patients with Parkinson’s disease.

27 Feb 2019

New analysis highlights increasing focus of early-stage clinical trials on rare cancers

The proportion of early-stage drug trials tackling the biggest cancer killers has declined sharply since the early 1990s as less common tumor types receive increasing attention, according to new research to be presented during the International Congress on Targeted Anticancer Therapies 2019, taking place from today to 27 February in Paris, France.

25 Feb 2019

Clinical study shows tolerability and safety of investigational drug in boys with DMD

Patients with Duchenne muscular dystrophy have few treatment options. Medications currently available or in development either target only a subset of DMD patients with a particular genetic mutation or cause significant side effects.

23 Feb 2019

Phase 1 data reinforce safety profile of new drug for treating Duchenne muscular dystrophy

Patients with Duchenne muscular dystrophy (DMD) have few treatment options. Medications currently available or in development either target only a subset of DMD patients with a particular genetic mutation or cause significant side effects.

21 Feb 2019

Drug increases melanin production in some people with albinism

A small pilot clinical study at the National Eye Institute suggests that the drug nitisinone increases melanin production in some people with oculocutaneous albinism type 1B, a rare genetic disease that causes pale skin and hair and poor vision.

21 Feb 2019

'Trojan horse' drug shows promise for untreatable cancers

A new cancer drug that uses a ‘Trojan horse’ approach to destroy cancer cells from within has shown promising results for patients with untreatable cancers.

8 Feb 2019

Immunotherapy drug found to be effective in patients with advanced Merkel cell carcinoma

A multi-center phase II clinical trial investigating pembrolizumab as a first-line and programmed cell death-1 therapy in patients with advanced Merkel cell carcinoma reports lasting tumor control, generally manageable side effects and improved overall survival.

8 Feb 2019

New acute porphyria treatment shows promising results in clinical study

Acute porphyria is a group of uncommon diseases that can cause severe, potentially life-threatening attacks of abdominal pain, nausea, vomiting and paralysis. Liver transplantation is currently the only effective treatment available for the most seriously afflicted patients.

7 Feb 2019

Study: Promising new treatment for children with ADHD shows improvement in efficacy

A new study in children aged 6 to 12 years of dasotraline, a promising new treatment for attention deficit hyperactivity disorder, showed significant improvement in efficacy in the treatment of ADHD compared to placebo beginning at week 1 and continuing throughout the study.

4 Feb 2019

SCYNEXIS announces positive results from first interim efficacy analysis of FURI study

SCYNEXIS, Inc., a biotechnology company delivering innovative therapies for difficult-to-treat and often life-threatening infections, today announced positive results from the first interim efficacy analysis of the ongoing FURI study.

1 Feb 2019

Human trials set to begin for testing new 'fat pill' in overweight patients

Are you overweight and living in the South East of England? If so, you could help scientists who need volunteers to test a new 'fat pill'.

29 Jan 2019

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