Genomics

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Yale scientists develop advanced CRISPR tool to study complex genetic interactions

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases.

20 Mar 2025

Scientists uncover hints of a potential new cause of stomach cancer

For the first time, scientists have systematically analyzed somatic mutations in stomach lining tissue to unpick mutational processes, some of which can lead to cancer.

19 Mar 2025

New tool visualizes immune response to abnormal DNA

A research led by Sergio P. Acebrón, Researcher Ikerbasque at the UPV/EHU, develops a key tool to visualize the immune response to abnormal DNA, opening new avenues for the treatment of diseases.

19 Mar 2025

New RNA barcoding method tracks gene transfer in microbial communities

In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive antibiotic resistance and even shape entire ecosystems.

19 Mar 2025

Researchers challenge the genetic paradigm of cancer

It's time for researchers to reconsider the current paradigm of cancer as a genetic disease, argued Sui Huang from the Institute for Systems Biology, USA, and colleagues in a new essay published March 18th in the open-access journal PLOS Biology.

19 Mar 2025

Ancient genetic mixing shaped the evolution of modern humans

Modern humans descended from not one, but at least two ancestral populations that drifted apart and later reconnected, long before modern humans spread across the globe.

18 Mar 2025

Identifying genetic resistance factors and antimicrobial resistance phenotypes in MRSA strains

With the rising prevalence of methicillin-resistant Staphylococcus (S.) aureus (MRSA), a multi drug resistant strain, treatment has become a challenge.

18 Mar 2025

NKD2 protein discovery opens up new possibilities in the fight against bone loss

A transformative study has uncovered the pivotal role of the protein Naked cuticle homolog 2 (NKD2) in regulating the differentiation of bone-forming osteoblasts and bone-resorbing osteoclasts.

17 Mar 2025

Researchers discover MAFB and CEBPA’s role in hypospadias pathogenesis

Hypospadias is characterized by an ectopic urethral opening and abnormal penile curvature, affecting approximately 1 in 200 live male births.

17 Mar 2025

Baylor study sheds light on role of CDKL1 and CDKL2 in neurodevelopmental disorders

CDKL5, one of the five members of the CDKL family of genes, is important for proper neurodevelopment and associated with seizures.

14 Mar 2025

Mitochondria may hold key to reducing inflammaging in aging cells

In humans and other multicellular organisms, cells multiply. This defining feature allows embryos to grow into adulthood, and enables the healing of the many bumps, bruises and scrapes along the way.

14 Mar 2025

Study unveils mechanisms behind antigenic variation in pathogens

A new study by LMU and Helmholtz Munich shows how pathogens control changes in their cell surface to evade the immune system.

14 Mar 2025

CRISPR technologies paving the way for advances in regenerative medicine

A recent review published in the journal Engineering delves into the significant advancements and potential of CRISPR technologies in the field of regenerative medicine.

13 Mar 2025

People from families with exceptional longevity have lower risk of peripheral artery disease

A new research paper was published in Aging (Aging-US) on February 25, 2025, Volume 17, Issue 2, titled "Epidemiology and genetic determination of measures of peripheral vascular health in the Long Life Family Study."

12 Mar 2025

Updates on influenza vaccine strain recommended by WHO (2025-2026 northern hemisphere)

To maintain vaccine efficacy, WHO regularly updates influenza vaccine strains based on global epidemiological, virological, and serological analyses.

From Sino Biological Inc. 12 Mar 2025

Gilead’s capsid revolution meets our capsid solutions: Sino Biological – Engineering the tools to outsmart HIV

Gilead Sciences announced a significant milestone: the U.S. FDA accepted their New Drug Applications (NDAs) for lenacapavir (LEN), a groundbreaking twice-yearly injectable HIV-1 capsid inhibitor for pre-exposure prophylaxis (PrEP).

From Sino Biological Inc. 12 Mar 2025

Harnessing lncRNAs for early diagnosis and intervention in acute kidney injury

A new review published in Genes & Diseases on long non-coding RNAs (lncRNAs) highlights their critical role in the development, diagnosis, and potential treatment of acute kidney injury (AKI) and chronic kidney disease (CKD). The findings emphasize the importance of exosomal lncRNAs, which function as molecular regulators in kidney pathology and hold promise for future biomarker discovery and therapeutic advancements.

11 Mar 2025

Ovarian cancer mutations across populations show similarities and unique differences

An extensive tumor genomic analysis of individuals with ovarian cancer, led by researchers from Huntsman Cancer Institute at the University of Utah (the U) and Emory University, revealed that Black women have nearly identical mutations to other previously studied populations.

10 Mar 2025

UF researchers develop AI tool to tackle ancestral bias in precision medicine

University of Florida researchers are addressing a critical gap in medical genetic research - ensuring it better represents and benefits people of all backgrounds.

10 Mar 2025

Study links ITSN1 gene variants to increased Parkinson's disease risk

A new study published in Cell Reports reveals a breakthrough discovery linking genetic variants in the gene ITSN1 to a significantly elevated risk of Parkinson's disease, a neurodegenerative condition that affects nearly 2% of adults older than 65 years.

7 Mar 2025

Genomics

Yale scientists develop advanced CRISPR tool to study complex genetic interactions

Scientists uncover hints of a potential new cause of stomach cancer

New tool visualizes immune response to abnormal DNA

New RNA barcoding method tracks gene transfer in microbial communities

Researchers challenge the genetic paradigm of cancer

Ancient genetic mixing shaped the evolution of modern humans

Identifying genetic resistance factors and antimicrobial resistance phenotypes in MRSA strains

NKD2 protein discovery opens up new possibilities in the fight against bone loss

Researchers discover MAFB and CEBPA’s role in hypospadias pathogenesis

Baylor study sheds light on role of CDKL1 and CDKL2 in neurodevelopmental disorders

Mitochondria may hold key to reducing inflammaging in aging cells

Study unveils mechanisms behind antigenic variation in pathogens

CRISPR technologies paving the way for advances in regenerative medicine

People from families with exceptional longevity have lower risk of peripheral artery disease

Updates on influenza vaccine strain recommended by WHO (2025-2026 northern hemisphere)

Gilead’s capsid revolution meets our capsid solutions: Sino Biological – Engineering the tools to outsmart HIV

Harnessing lncRNAs for early diagnosis and intervention in acute kidney injury

Ovarian cancer mutations across populations show similarities and unique differences

UF researchers develop AI tool to tackle ancestral bias in precision medicine

Study links ITSN1 gene variants to increased Parkinson's disease risk

Prof. Dr. Kristina Kusche-Vihrog

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