Genomics

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Groundbreaking study reveals secrets of Drosophila uterus

You have likely not spent much time thinking about the uterus of the fruit fly, Drosophila melanogaster.

26 Oct 2024

Common plastic ingredient causes breaks in DNA strands and chromosome errors

A new study conducted in roundworms finds that a common plastic ingredient causes breaks in DNA strands, resulting in egg cells with the wrong number of chromosomes.

25 Oct 2024

ClinGen publishes data on over 2700 genes relevant to genetic diseases

The Clinical Genome Resource (ClinGen), a National Institutes of Health (NIH)-funded resource that works to define the clinical relevance of genes and variants, has published data on more than 2,700 genes curated for relevance to genetic diseases, including cancer, cardiovascular disease and neurodevelopmental disorders.

25 Oct 2024

FUSE: Revolutionizing the analysis of gene mutations

Our study introduces a new tool called FUSE (Functional Substitution Estimation) that helps scientists better understand how changes in genes affect proteins.

25 Oct 2024

Researchers uncover why the TP53 gene is especially prone to mutations in cancer

Mutations in the fragile TP53 gene impair p53's tumor-suppressive functions, making it more vulnerable than other tumor suppressors.

24 Oct 2024

Gene named after Irish folklore may aid recovery from nerve injuries

The key to recovering from traumatic nerve injuries, like those sustained in motor vehicle accidents or gunshot wounds, may be a gene named for the land of everlasting youth in Irish folklore.

24 Oct 2024

Study reveals hormone receptors' role in brain health and neuroprotection

In a comprehensive review published in the October 2024 issue of Genomic Psychiatry, researchers have unveiled crucial insights into how two types of hormone receptors collaborate to maintain brain health and potentially prevent neurodegenerative diseases.

24 Oct 2024

PacBio Onso™ short read sequencing instrument joins 10X Genomics compatible partner program

PacBio (PACB), a leading developer of high-quality, highly accurate genomic sequencing solutions, today announced the inclusion of the Onso short-read sequencing platform in the 10x Genomics Compatible Partner Program.

From PacBio 23 Oct 2024

Study connects brain volume variations with genetic risk factors for Parkinson’s disease and ADHD

Unprecedented genome analysis reveals genetic links between brain structure and disorders like Parkinson's and ADHD, paving the way for innovative treatments.

23 Oct 2024

Structural biology reveals secrets of DEV phage infection

The viruses that infect bacteria are the most abundant biological entities on the planet. For example, a recent simple study of 92 showerheads and 36 toothbrushes from American bathrooms found more than 600 types of bacterial viruses, commonly called bacteriophages or phages.

22 Oct 2024

New insights into how gene transcription influences genome motion

A team of scientists has discovered surprising connections among gene activity, genome packing, and genome-wide motions, revealing aspects of the genome's organization that directly affect gene regulation and expression.

22 Oct 2024

Research sheds new light on the behavior of KRAS gene in pancreatic and colorectal cancer

Recent research from the University of Helsinki sheds new light on the behavior of the KRAS gene in two of the deadliest cancers—pancreatic and colorectal cancer.

21 Oct 2024

Researchers identify genetic links to brain volume and disorders

In one of the largest-ever studies of DNA and brain volume, researchers have identified 254 genetic variants that shape key structures in the "deep brain," including those that control memory, motor skills, addictive behaviors and more.

21 Oct 2024

New technique enhances understanding of chromatin organization

Researchers at the University of California San Diego Center for Epigenomics (C4E) have developed a new technique, called Droplet Hi-C, that allows scientists to rapidly determine chromatin organization, the arrangement of genetic material within cells.

18 Oct 2024

Ancient DNA reveals insights into starch digestion

If you've ever struggled to reduce your carb intake, ancient DNA might be to blame. It has long been known that humans carry multiple copies of a gene that allows us to begin breaking down complex carbohydrate starch in the mouth, providing the first step in metabolizing starchy foods like bread and pasta.

18 Oct 2024

DNA barcoding reveals hidden species diversity

The Earth is an almost unimaginably diverse planet in terms of species. Researchers have identified between two and three million species, but there are many more that we know nothing about.

18 Oct 2024

Scientists map the genetic landscape of drug resistance in cancers

All cancer mutations that cause drug resistance fall into one of four categories. New research has detailed each type, helping to uncover targets for drug development and identify potential effective second-line therapies.

18 Oct 2024

New research highlights genetics as key factor in BMI and obesity risk

Genomics’ latest groundbreaking research, showcased at the Bupa Health Symposium, shows that a person’s genetic background is a key driver for their BMI and therefore is crucial to understanding their risk of obesity.

18 Oct 2024

Study identifies genetic associations with youth psychopathology

When trying to understand how genetic influences factor into youth behavior, researchers at Washington University in St. Louis have taken the "big trawl" approach, casting their net wide to pull in all the measured traits, behaviors and environments that make up who we are and examine associations with the genetic building blocks comprising risk for mental health problems.

17 Oct 2024