Genomics

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Newly identified enzyme provides a new tool in CRISPR genome editing toolbox

A recently discovered hypercompact CRISPR enzyme found only in huge bacteriophages, and known as CRISPR-CasΦ, is functional, a new study by Patrick Pausch, Jennifer Doudna and colleagues reports, and it provides a powerful new tool in the CRISPR genome editing toolbox, including because it can target a wider range of genetic sequences compared to Cas9 and Cas12.

17 Jul 2020

Researchers solve the mystery of genetic defect in horses

Warmblood fragile foal syndrome is a severe, usually fatal, genetic disease that manifests itself after birth in affected horses.

16 Jul 2020

RNA editing may repair the underlying cause of Rett Syndrome in mouse model

A genomic error that causes Rett Syndrome, a serious lifelong neurological disorder, can be corrected in the brains of mice by rewriting the genetic instructions carried by the RNA.

15 Jul 2020

Nix gene can help develop future mosquito control techniques

Virginia Tech researchers have proven that a single gene can convert female Aedes aegypti mosquitoes into fertile male mosquitoes and identified a gene needed for male mosquito flight.

15 Jul 2020

Your biology may play a role in feeling insecure about romantic relationships

Imagine tracking your feelings during daily interactions with your romantic partner. What would you learn? That's what approximately 100 heterosexual couples in Montreal did each day for 3 weeks during a study run by researchers from McGill University.

14 Jul 2020

Researchers develop novel tool to maximize the power of deep learning for genomic studies

Researchers from the MDC have developed a new tool that makes it easier to maximize the power of deep learning for studying genomics.

13 Jul 2020

Study sheds new light on neurobiological processes that control drug-related adaptations

The lab of Jeremy Day, Ph.D., at the University of Alabama at Birmingham, has used single-nucleus RNA sequencing approaches to compare transcriptional responses to acute cocaine in 16 unique cell populations from a portion of the brain called the nucleus accumbens, or NAc.

10 Jul 2020

Overzealous guardians in the cells could increase cancer risk

Researchers at the UiO and OUS have discovered how destructive changes occur in our genome. This could lead to cancer. Their results have been published in the journal Nature Cell Biology.

9 Jul 2020

Genomics can perpetuate inequality and structural racism

Genomics is crowding out ways of reducing inequality, has thwarted medicine from advancing justice, and is creating new forms of social classification and surveillance.

9 Jul 2020

Researchers use gene-editing techniques to visualize protein action in multicellular animals

Duke University researchers have made the first time-lapse movies of the sheet-like latticework that surrounds and supports most animal tissues.

9 Jul 2020

Researchers map non-coding, 'functional' genome in maize during early reproductive development

Growth and development of all organisms depends on coordinated regulation of gene expression in time and space, and this is largely controlled by non-coding sequences in the genome.

8 Jul 2020

Neuronal subtypes that drive locomotion in fruit fly reveal an unexpected diversity

A new study by MIT neuroscientists into how seemingly similar neuronal subtypes drive locomotion in the fruit fly revealed an unexpected diversity as the brain's commands were relayed to muscle fibers.

8 Jul 2020

Untargeted metabolomics can determine genetic variant to improve patient diagnosis

A patient and family walk into a doctor's office. They hope that the latest tests will reveal what is causing the patient's illness and end the diagnostic odyssey they have been going through for years.

8 Jul 2020

DNA resection pathways are highly specific, shows study

Our cells are constantly dividing, and as they do, the DNA molecule - our genetic code - sometimes gets broken. DNA has twin strands, and a break in both is considered especially dangerous.

7 Jul 2020

Study: Group genomics are responsible for aggression in Africanized honey bees

Researchers often study the genomes of individual organisms to try to tease out the relationship between genes and behavior.

7 Jul 2020

Researchers create new tool to identify cancer-causing mutations lurking in 98% of the genome

Gene coding regions constitute 2% of the human genome. St. Jude Children's Research Hospital scientists have developed a computational tool to identify alterations that drive tumor formation in the remaining 98% of the genome.

6 Jul 2020

Study: Variation in COVID-19 viral genome improves its ability to infect human cells

Researchers have shown that a variation in the viral genome of Covid-19 improved its ability to infect human cells and helped it become the dominant strain circulating around the world today.

3 Jul 2020

Scientists test evolutionary fitness of older-mother offspring in various environments

The offspring of older mothers don't fare as well as those of younger mothers, in humans and many other species. They aren't as healthy, or they don't live as long, or they have fewer offspring themselves.

2 Jul 2020

NIH announces $75 million in funding to improve genomic risk assessments for diverse populations

The National Institutes of Health has announced the provision of $75 million in funding over five years for the Electronic Medical Records and Genomics (eMERGE) Genomic Risk Assessment and Management Network, which establish protocols and methodologies for improved genomic risk assessments for diverse populations and to integrate their use in clinical care.

1 Jul 2020

A data-rich atlas of the developing human brain

For the nascent brain of a human embryo to develop into the complex organ that controls human consciousness, a finely tuned sequence of genetic events has to take place; hundreds of genes are activated and deactivated in a precise symphony.

30 Jun 2020

Genomics

Newly identified enzyme provides a new tool in CRISPR genome editing toolbox

Researchers solve the mystery of genetic defect in horses

RNA editing may repair the underlying cause of Rett Syndrome in mouse model

Nix gene can help develop future mosquito control techniques

Your biology may play a role in feeling insecure about romantic relationships

Researchers develop novel tool to maximize the power of deep learning for genomic studies

Study sheds new light on neurobiological processes that control drug-related adaptations

Overzealous guardians in the cells could increase cancer risk

Genomics can perpetuate inequality and structural racism

Researchers use gene-editing techniques to visualize protein action in multicellular animals

Researchers map non-coding, 'functional' genome in maize during early reproductive development

Neuronal subtypes that drive locomotion in fruit fly reveal an unexpected diversity

Untargeted metabolomics can determine genetic variant to improve patient diagnosis

DNA resection pathways are highly specific, shows study

Study: Group genomics are responsible for aggression in Africanized honey bees

Researchers create new tool to identify cancer-causing mutations lurking in 98% of the genome

Study: Variation in COVID-19 viral genome improves its ability to infect human cells

Scientists test evolutionary fitness of older-mother offspring in various environments

NIH announces $75 million in funding to improve genomic risk assessments for diverse populations

A data-rich atlas of the developing human brain

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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