Genomics

RSS

New solution can limit spread of wild-released gene drives to target populations

By altering the heritability of certain traits, gene drive technologies have the potential to spread desired genes through wild populations.

10 Oct 2019

Study sheds light on how human gut microbes break down processed foods

A new study from Washington University School of Medicine in St. Louis sheds light on how human gut microbes break down processed foods - especially potentially harmful chemical changes often produced during modern food manufacturing processes.

9 Oct 2019

Cholera pathogen can acquire large stretches of genetic material from neighboring bacteria

In 2015, EPFL researchers led by Melanie Blokesch published a seminal paper in Science showing that the bacterium responsible for cholera, Vibrio cholerae, uses a spring-loaded spear to literally stab neighboring bacteria and steal their DNA.

8 Oct 2019

Histone modifications play important role in 'zygotic genome activation'

Scientists at Tokyo Institute of Technology observed changes to the gene-regulating factors during zebrafish development and discovered that modifications to "histone H3", one of the proteins around which DNA is bound, play an important role in "zygotic genome activation" or transition of control of zebrafish embryonic development from maternal material to the zygote .

8 Oct 2019

DNA metabarcoding could improve analysis of human diet

A study has shown that DNA metabarcoding serves as a powerful new tool for monitoring humans’ intake of plants.

8 Oct 2019

New study advances understanding about what shapes human gut microbiome

A new Northwestern University study finds that despite human's close genetic relationship to apes, the human gut microbiome is more similar to that of Old World monkeys like baboons than to that of apes like chimpanzees.

8 Oct 2019

Carnegie Mellon and Yale win NIH grant to advance gene editing technique

A research team from Carnegie Mellon University and Yale University will advance their innovative, synthetic nucleic acid-based gene editing technique under a new grant from the National Institutes of Health's Somatic Cell Genome Editing Program.

7 Oct 2019

Common genetic variant explains why immunotherapy often fails in Crohn's disease

The reason why a commonly used range of immunotherapy drugs is not effective in some patients with Crohn’s disease has so far not been identified, until now.

7 Oct 2019

Scientists use organoid technology to achieve stable long-term cultures of mouse urothelial cells

Investigation of biological mechanisms in urothelial tissue -one of the three types of tissue that make up the urinary system- has always been very limited due to the lack of technologies that allow working with stable and long-term populations of the cells that compose it.

4 Oct 2019

Stanford study finds genetic similarities among species that use sound waves to navigate

Insect-eating bats navigate effortlessly in the dark and dolphins and killer whales gobble up prey in murky waters thanks in part to specific changes in a set of 18 genes involved in the development of the cochlear ganglion -- a group of nerves that transmit sound from the ear to the brain, according to a study by researchers at Stanford University.

4 Oct 2019

The atomic-level structure of DNA polymerase delta – the enzyme behind DNA replication

A new study has revealed how the fundamental enzyme called DNA polymerase delta operates during DNA replication, making a copy of the genetic code that can be transmitted through the generations.

4 Oct 2019

ATCC launches new database of reference-quality genome sequences to aid biological research

ATCC launched its new ATCC Genome Portal, a publicly available database of reference-quality genome sequences matched to authenticated ATCC biological materials that will help researchers interpret and reproduce their results with confidence.

From American Type Culture Collection (ATCC) 4 Oct 2019

Novel viral vector improves gene therapy for sickle cell disease

Researchers at the National Institutes of Health (NIH) have developed a unique, improved lentiviral vector for use in gene therapy for sickle cell disease.

3 Oct 2019

Researchers to explore if humans can exploit genetics of a mouse that regrows axons after injury

A bit more than a million years ago, a population of Southeastern Asian mice developed the remarkable ability to regrow axons after injury to its brain.

1 Oct 2019

New method for studying individual cells could lead to earlier detection of diseases

Researchers in Sweden and the U.S. have devised a new method for studying individual cells in human tissue, which could lead to even earlier detection of diseases such as cancer and ALS. The method offers a 1,400-fold increase in spatial resolution.

1 Oct 2019

Researchers identify new genetic signals for regulation of infant growth

Researchers at the University of Bergen in Norway have identified new genetic signals for the regulation of how infants grow. This may be a crucial step in the fight against growth-related diseases.

1 Oct 2019

New CRISPR-Cas9 variant has potential to increase precision during gene therapy

Researchers have developed a new variant of the gene editing technique CRISPR-Cas9 that has the potential to increase precision during gene therapy in humans.

30 Sep 2019

Cardiac cells derived from skin samples help unravel genetic underpinnings of heart function

Genome-wide association studies have uncovered more than 500 genetic variants linked to heart function, everything from heart rate to irregular rhythms that can lead to stroke, heart failure or other complications.

30 Sep 2019

RNA Targeted Small Molecules: Finally Drug the “Undruggable” RNA

At a time when the previously untapped drug discovery opportunity promised within RNA opens up, the 2nd RNA- Targeted Drug Discovery Summit returns to reunite the leading minds from large pharma, innovative biotech and KOLs of academia to overcome unique discovery and development challenges associated with novel RNA targeted small molecule therapeutics and achieve their seemingly limitless potential.

From RNA-Targeted Drug Discovery Summit 30 Sep 2019

Scientists use ultrasound to detect active genes in live cells

A startling new study shows that ultrasound can help scientists to understand whether specific genes are in the active or inactive state in live cells.

27 Sep 2019

Genomics

New solution can limit spread of wild-released gene drives to target populations

Study sheds light on how human gut microbes break down processed foods

Cholera pathogen can acquire large stretches of genetic material from neighboring bacteria

Histone modifications play important role in 'zygotic genome activation'

DNA metabarcoding could improve analysis of human diet

New study advances understanding about what shapes human gut microbiome

Carnegie Mellon and Yale win NIH grant to advance gene editing technique

Common genetic variant explains why immunotherapy often fails in Crohn's disease

Scientists use organoid technology to achieve stable long-term cultures of mouse urothelial cells

Stanford study finds genetic similarities among species that use sound waves to navigate

The atomic-level structure of DNA polymerase delta – the enzyme behind DNA replication

ATCC launches new database of reference-quality genome sequences to aid biological research

Novel viral vector improves gene therapy for sickle cell disease

Researchers to explore if humans can exploit genetics of a mouse that regrows axons after injury

New method for studying individual cells could lead to earlier detection of diseases

Researchers identify new genetic signals for regulation of infant growth

New CRISPR-Cas9 variant has potential to increase precision during gene therapy

Cardiac cells derived from skin samples help unravel genetic underpinnings of heart function

RNA Targeted Small Molecules: Finally Drug the “Undruggable” RNA

Scientists use ultrasound to detect active genes in live cells

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Latest Life Science News