Genomics

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Researchers take a step forward with a study of molecules of DNA

Researchers from the Andalusian center for Molecular Biology and regenerative Medicine and from the University of Seville have taken a step forward with a study of something as essential for life as the molecules of DNA.

5 Dec 2018

Ethnicity can be reliable indicator of gut microbiota diversity

Research increasingly links the gut microbiome to a range of human maladies, including inflammatory bowel disease, diabetes and even cancer. Attempts to manipulate the gut with food rich in healthy bacteria, such as yogurt or kombucha, are in vogue, along with buying commercial probiotics that promise to improve users' chances against illness.

4 Dec 2018

Selective survival of embryos under adverse conditions may explain health problems later in life

An international team led by researchers of the Leiden University Medical Center and Lund University in Sweden propose that selection of random epigenetic differences causes particular embryos to survive under adverse conditions in the womb.

4 Dec 2018

Cancer DNA signature will revolutionize point-of-care diagnostics

Researchers have developed a potentially game-changing new technology that could revolutionize cancer point-of-care (POC) diagnostics.

4 Dec 2018

Researcher discovers key differences in protein production between healthy cells and tumors

The human body is made up of more than 200 types of cell, from bone and brain to liver and lung. Each cell type is determined by the particular combination of proteins it produces.

4 Dec 2018

Study provides new insights into mechanisms used by cells to transmit genetic information

The integrity of the genome relies on the ability of the cells to build and maintain a well-defined boundary between the nuclear compartment and the cytoplasm, known as the nuclear envelope.

4 Dec 2018

NanoBioCel group develops lipid vesicles that can genetic material efficiently and viably

In a piece of research conducted in collaboration, the NanoBioCel group of the UPV/EHU's Faculty of Pharmacy, and the University of Elche have designed some niosomes, which are lipid vesicles for use in gene therapies designed to treat diseases of the central nervous system.

4 Dec 2018

Customizing Genetically Engineered Models for Specific Research Applications

In this interview conducted at SfN 2018, Philip Dubé from Taconic Biosciences, goes into detail about genetically engineered models and their importance in understanding neurodegenerative diseases.

From Taconic Biosciences, Inc. 4 Dec 2018

Epigenetic maps of the inner ear could lead to development of therapeutics for hearing loss

Epigenetics is the expression and control of genes. The epigenetics involved in the inner ear is a critical part of the mystery of hearing.

3 Dec 2018

Study identifies more than 6,000 antibiotic resistance genes found in gut bacteria

A study carried out in collaboration with the University of Birmingham has used an innovative approach to identify thousands of antibiotic resistance genes found in bacteria that inhabit the human gut.

3 Dec 2018

Light-activated tools allow scientists to accurately probe intracellular phase separation

Creating new tools that harness light to probe the mysteries of cellular behavior, Princeton researchers have made discoveries about the formation of cellular components called membraneless organelles and the key role these organelles play in cells.

30 Nov 2018

New study could fine-tune the CRISPR gene editing process

The introduction of the tool for gene editing, the so-called gene scissors CRISPR, in 2007 was a revolution within medical science and cell biology.

30 Nov 2018

New Mainz-based Collaborative Research Center aims to explore DNA repair and genome stability

From January 1, 2019, the German Research Foundation will be funding the new Collaborative Research Center 1361 on Regulation of DNA Repair & Genome Stability.

29 Nov 2018

New York State approves NYGC's Whole Genome and Transcriptome Sequencing for oncology

The New York Genome Center has received approval from the New York State Department of Health to offer whole genome and RNA transcriptome sequencing in its Clinical Laboratory Evaluation Program-certified laboratory.

29 Nov 2018

Discovery about DNA twists could be crucial in development of new antibiotics

DNA replication is vital to all lifeforms, but in some organisms, it can be prevented by twists in the DNA sequence, called 'supercoils'. If too many supercoils are allowed to build up, cells vital to sustaining life will die.

28 Nov 2018

Researchers map cells in the early human placenta to shed light on pregnancy complications

To treat and prevent pregnancy-related disorders, researchers must understand not only what can go wrong, but when. Complications, such as preeclampsia and pre-term birth, often occur in the second or third trimester, and most research to date has focused on those later stages of pregnancy. But the biological events that lead to these problems could start much earlier.

28 Nov 2018

Novel methodology for characterizing neurons could lead to better understanding of brain disease

It takes a lot of cells to make a human brain. The organ houses not only an enormous quantity of neurons (tens of billions), but also an impressive diversity of neuron types. In recent years, scientists have been developing inventories of these cell classes--information that will be essential for understanding how the brain works.

28 Nov 2018

New platform for metagenomic analysis

A team of developers from Skolkovo, ITMO University and MIPT presented an online service called Knomics-Biota, which allows for a comprehensive study of intestinal microbiome genetic data.

27 Nov 2018

ASHG reaffirms cautious but proactive approach recommended in its 2017 position statement on germline genome editing

Given this morning's reports of infants possibly born in China whose genomes were edited by CRISPR-based technology, the American Society of Human Genetics (ASHG) reaffirms the cautious but proactive approach recommended in its 2017 position statement on human germline genome editing, published in The American Journal of Human Genetics.

26 Nov 2018

International study of ADHD at genomic scale

An international study, focused on the analysis of the genome of more than 50,000 people worldwide, has identified twelve specific fragments of DNA related to the vulnerability of the attention deficit hyperactivity disorder.

26 Nov 2018

Genomics

Researchers take a step forward with a study of molecules of DNA

Ethnicity can be reliable indicator of gut microbiota diversity

Selective survival of embryos under adverse conditions may explain health problems later in life

Cancer DNA signature will revolutionize point-of-care diagnostics

Researcher discovers key differences in protein production between healthy cells and tumors

Study provides new insights into mechanisms used by cells to transmit genetic information

NanoBioCel group develops lipid vesicles that can genetic material efficiently and viably

Customizing Genetically Engineered Models for Specific Research Applications

Epigenetic maps of the inner ear could lead to development of therapeutics for hearing loss

Study identifies more than 6,000 antibiotic resistance genes found in gut bacteria

Light-activated tools allow scientists to accurately probe intracellular phase separation

New study could fine-tune the CRISPR gene editing process

New Mainz-based Collaborative Research Center aims to explore DNA repair and genome stability

New York State approves NYGC's Whole Genome and Transcriptome Sequencing for oncology

Discovery about DNA twists could be crucial in development of new antibiotics

Researchers map cells in the early human placenta to shed light on pregnancy complications

Novel methodology for characterizing neurons could lead to better understanding of brain disease

New platform for metagenomic analysis

ASHG reaffirms cautious but proactive approach recommended in its 2017 position statement on germline genome editing

International study of ADHD at genomic scale

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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