Genomics

RSS

Pfizer to use BC Platforms’ technology solutions to analyze data in cardiovascular diseases

BC Platforms, a world leader in genomic data management and analytics, today announces that Pfizer Finland will be using its technology solutions and research platform, including BCRQUEST.COM, to study data in cardiovascular diseases.

14 Feb 2018

Pioneering research could provide novel insight into how genomic information is read

Pioneering new research could offer a fascinating new insight into how genomic information is read. The human genome contains thousands of genes, but to get the information from a gene requires it to be copied.

13 Feb 2018

New findings about fruit fly's body temperature rhythms may help people sleep better

In findings that one day may help people sleep better, scientists have uncovered the first molecular evidence that two anciently conserved proteins in the brains of insects and mammals share a common biological ancestry as regulators of body temperature rhythms crucial to metabolism and sleep.

13 Feb 2018

Hints to aging lurk in fruit flies’ germline stem cells

Little hints of immortality are lurking in the stem cells of fruit flies. Stem cells that produce sperm use a genetic trick to stay perpetually young across generations, researchers at the University of Michigan Life Sciences Institute have discovered. Certain sections of the fruit fly genome get shorter with age. But remarkably, some reproductive cells can repair the shrinkage, the researchers report in the journal eLife.

13 Feb 2018

Tissue-specific changes in gene expression can help predict time of death

International team of scientists led by Roderic Guigó at the Centre for Genomic Regulation in Barcelona showed that changes in gene expression in different tissues triggered by death can be used to predict the time of death of an individual.

13 Feb 2018

Scientists develop Scanpy software to analyze enormous single-cell data

Scientists from the Helmholtz Zentrum München have developed a program that is able to help manage enormous datasets.

13 Feb 2018

Ground-breaking partnership aims to deliver faster, more accurate diagnoses for genetic epilepsy

New software to deliver faster and more accurate diagnoses in genetic epilepsies is the ambition of a ground-breaking partnership between Congenica, a global provider of clinical genomics interpretation software, and FutureNeuro, the SFI Research Centre for Chronic and Rare Neurological Diseases, supported by Science Foundation Ireland.

13 Feb 2018

Scientists use novel epigenetic-centered techniques to inhibit cancer metastases

In one of the first successes of its kind, researchers from Case Western Reserve University School of Medicine and six other institutions have inhibited the spreading of cancer cells from one part of the body to another.

12 Feb 2018

Scientists develop ultrasound-propelled nanomotors for active delivery of Cas9-sgRNA complex

In cancer research, the “Cas-9–sgRNA” complex is an effective genomic editing tool, but its delivery across the cell membrane to the target (tumor) genome has not yet been satisfactorily solved. American and Danish scientists have now developed an active nanomotor for the efficient transport, delivery, and release of this gene scissoring system.

9 Feb 2018

Scientists identify special pair of RNA scissors with many functions

CRISPR/Cas systems are known as promising "gene scissors" in the genome editing of plants, animals, and microorganisms by targeting specific regions in their DNA - and perhaps they can even be used to correct genetic defects.

8 Feb 2018

Novel technology platform for custom designing bacteriophages

Bacteriophages, known informally as phages, are viruses that can attack and kill specific bacteria. They occur everywhere in the natural world. Precisely because they are matched to just one specific type of bacteria, researchers and medics hope that phages can be engineered to combat certain bacterial infections.

7 Feb 2018

New CRISPR gene-editing technique can correct majority of mutations that cause DMD

Scientists have developed a CRISPR gene-editing technique that can potentially correct a majority of the 3,000 mutations that cause Duchenne muscular dystrophy (DMD) by making a single cut at strategic points along the patient's DNA, according to a study from UT Southwestern Medical Center.

6 Feb 2018

Scientists develop new system to match genetic anomalies with precision medicine treatments

A team of computer scientists from the University of Delaware and Georgetown University has developed a new system to rapidly determine which cancer drugs are likely to work best given a patient's genetic markers.

6 Feb 2018

Next-generation ‘active genetics’ tool opens new horizons

In 2015, University of California San Diego biologists Ethan Bier and Valentino Gantz developed a breakthrough technology known as "active genetics," which results in parents transmitting a genetic trait to most of their offspring (instead of 50 percent receiving the trait under standard inheritance).

6 Feb 2018

Detailed phenotypic information on resistance genes can guide future drug development

The genes that are able to equip bacteria with resistance to clinically used antibiotics have been found in many different natural environments. Nevertheless, a functional overview of the resistance genes found in common human bacterial pathogens has been missing so far.

6 Feb 2018

Scientists discover rare hypertension disease gene

More than a billion people worldwide suffer from high blood pressure (hypertension). Prolonged hypertension damages blood vessels, which can result in damage to the heart, the kidneys, and the brain. Possible consequences include heart attack, kidney failure, and stroke.

5 Feb 2018

Novel method can edit genes with substantially fewer errors

Gene therapy is an emerging strategy to treat diseases caused by genetic abnormalities. One form of gene therapy involves the direct repair of a defective gene, using genome-editing technology such as CRISPR-Cas9. Despite its therapeutic potential, genome editing can also introduce unwanted and potentially harmful genetic errors that limit its clinical feasibility.

5 Feb 2018

Genomics

Pfizer to use BC Platforms’ technology solutions to analyze data in cardiovascular diseases

Pioneering research could provide novel insight into how genomic information is read

New findings about fruit fly's body temperature rhythms may help people sleep better

Hints to aging lurk in fruit flies’ germline stem cells

Tissue-specific changes in gene expression can help predict time of death

Scientists develop Scanpy software to analyze enormous single-cell data

Ground-breaking partnership aims to deliver faster, more accurate diagnoses for genetic epilepsy

Scientists use novel epigenetic-centered techniques to inhibit cancer metastases

Scientists develop ultrasound-propelled nanomotors for active delivery of Cas9-sgRNA complex

Scientists identify special pair of RNA scissors with many functions

Novel technology platform for custom designing bacteriophages

New CRISPR gene-editing technique can correct majority of mutations that cause DMD

Scientists develop new system to match genetic anomalies with precision medicine treatments

Next-generation ‘active genetics’ tool opens new horizons

Detailed phenotypic information on resistance genes can guide future drug development

Scientists discover rare hypertension disease gene

Novel method can edit genes with substantially fewer errors

Higher susceptibility of some babies to Zika virus has a genetic origin, study shows

Study reveals the mechanism of common DNA mutations

New ChIPseq kit is optimized for fresh and frozen tissue samples

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Latest Life Science News