Genomics

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Timing of mutations can have effect on health and disease

A single genetic mutation can lead to completely different diseases, depending on the time and location at which the mutation occurs.

30 Jun 2017

Research provides new insights into how telomeres regulate cellular senescence

Researchers at the Institute of Molecular Biology and Johannes Gutenberg University Mainz have further uncovered the secrets of telomeres, the caps that protect the ends of our chromosomes.

30 Jun 2017

Differential RNA splicing may play role in prostate cancer disparities in African-American men

A form of genetic variation, called differential RNA splicing, may have a role in tumor aggressiveness and drug resistance in African American men with prostate cancer.

30 Jun 2017

Cole-Parmer introduces Arcis Sample Prep Kit to extract DNA and RNA for downstream processes

Cole-Parmer, a leading supplier of laboratory equipment and reagents, is introducing the Arcis Sample Preparation System, which can extract DNA and RNA for downstream processes such as PCR/qPCR and sequencing in just three minutes.

From Cole Parmer Limited 30 Jun 2017

Genetic differences may play role in vision impairment, eye abnormalities of some astronauts

Researchers have found that genetic variation may increase susceptibility of some astronauts to develop higher-than-normal carbon dioxide levels in the blood, which may contribute to eye abnormalities, including grooved bands on the retina in the eye and swelling of the optic nerve.

29 Jun 2017

Researchers trace origins of AML relapse to rare therapy-resistant stem cells

Leukemia researchers led by Dr. John Dick have traced the origins of relapse in acute myeloid leukemia (AML) to rare therapy-resistant leukemia stem cells that are already present at diagnosis and before chemotherapy begins.

29 Jun 2017

Researchers suggest new strategy to identify germline mutations in men with prostate cancer

Scientists have had limited success at identifying specific inherited genes associated with prostate cancer, despite the fact that it is one of the most common non-skin cancers among men.

29 Jun 2017

Proteins impeding antitumor immunity could be 'Achilles heel' of some cancers

By comparing variations in protein expression in tumor samples from a single melanoma patient, researchers from the Johns Hopkins Bloomberg~Kimmel Institute and the Memorial Sloan-Kettering Cancer Center say their findings have the potential to reveal some of the mechanisms underlying response or resistance to immunotherapy drugs.

28 Jun 2017

Engineers take closer look at mechanical and chemical attributes of heart defect

Elastin and collagen serve as the body's building blocks. They provide tensile strength and elasticity for a number of organs, muscles and tissues. Any genetic mutation short-circuiting their function can have a devastating, and often lethal, health impact.

28 Jun 2017

Fluorescent proteins found in jellyfish shed new light on DNA copying

Using these proteins, originally found in jellyfish to make them glow, the team where able to focus laser beams on the brightly lit proteins and track them inside a bacteria that normally lives inside the human gut.

28 Jun 2017

Scientists show way to edit genome of disease-carrying mosquitoes

Scientists at UC Berkeley and UC Riverside have demonstrated a way to edit the genome of disease-carrying mosquitoes that brings us closer to suppressing them on a continental scale.

28 Jun 2017

Scientists link new gene clusters to poor breast cancer prognosis

Breast cancer patients could get more reliable idea of how long they will live now scientists have linked a new group of genes to poor prognosis.

28 Jun 2017

Scientists investigate genetics of windborne bacteria arriving along with dust

Israel is subjected to sand and dust storms from several directions: northeast from the Sahara, northwest from Saudi Arabia and southwest from the desert regions of Syria. The airborne dust carried in these storms affects the health of people and ecosystems alike.

28 Jun 2017

Study finds link between gene mutation and retinitis pigmentosa in U.S. Hispanic families

Thirty-six percent of Hispanic families in the U.S. with a common form of retinitis pigmentosa got the disease because they carry a mutation of the arrestin-1 gene, according to a new study from researchers at The University of Texas Health Science Center at Houston School of Public Health.

27 Jun 2017

Elevated levels of suPAR protein combine with genetic mutation to trigger CKD in black people

Between 15 and 20 percent of black people carry a genetic mutation that puts them at risk for certain chronic kidney disease, but only about half of them develop the illness – a variance that long has puzzled researchers.

27 Jun 2017

Study sheds light on night work−cancer link

A new study has offered insights into the association between night shift work and increased cancer risk, as well as pointing towards a potential solution. For several years, scientists have thought that disruption to the body’s natural circadian rhythm is accountable for the increased cancer risk, but the mechanisms behind this have not yet been pinpointed.

27 Jun 2017

Innate immune cells of myeloid lineage play central role in AD pathogenesis than previously thought

Many genes linked to late-onset Alzheimer's disease (AD) are expressed in myeloid cells and regulated by a single protein, according to research conducted at the Icahn School of Medicine at Mount Sinai and published June 19 in the journal Nature Neuroscience.

27 Jun 2017

Existing drugs could help subgroup of patients with osteosarcoma, suggest scientists

A subgroup of patients with osteosarcoma - a form of bone cancer - could be helped by an existing drug, suggest scientists from the Wellcome Trust Sanger Institute and their collaborators at University College London Cancer Institute and the Royal National Orthopaedic Hospital NHS Trust.

23 Jun 2017

Cancer cells may lose copies of ribosomal DNA to enable faster proliferation, study shows

Research from the Stowers Institute provides evidence suggesting that cancer cells might streamline their genomes in order to proliferate more easily.

23 Jun 2017

Scientists discover link between sugar metabolism and peroxisomal biogenesis disorders

Meeting a young patient with Zellweger syndrome, a rare, life-threatening genetic disease, started a scientific investigation that culminated with an unexpected discovery.

23 Jun 2017

Genomics

Timing of mutations can have effect on health and disease

Research provides new insights into how telomeres regulate cellular senescence

Differential RNA splicing may play role in prostate cancer disparities in African-American men

Cole-Parmer introduces Arcis Sample Prep Kit to extract DNA and RNA for downstream processes

Genetic differences may play role in vision impairment, eye abnormalities of some astronauts

Researchers trace origins of AML relapse to rare therapy-resistant stem cells

Researchers suggest new strategy to identify germline mutations in men with prostate cancer

Proteins impeding antitumor immunity could be 'Achilles heel' of some cancers

Engineers take closer look at mechanical and chemical attributes of heart defect

Fluorescent proteins found in jellyfish shed new light on DNA copying

Scientists show way to edit genome of disease-carrying mosquitoes

Scientists link new gene clusters to poor breast cancer prognosis

Scientists investigate genetics of windborne bacteria arriving along with dust

Study finds link between gene mutation and retinitis pigmentosa in U.S. Hispanic families

Elevated levels of suPAR protein combine with genetic mutation to trigger CKD in black people

Study sheds light on night work−cancer link

Innate immune cells of myeloid lineage play central role in AD pathogenesis than previously thought

Existing drugs could help subgroup of patients with osteosarcoma, suggest scientists

Cancer cells may lose copies of ribosomal DNA to enable faster proliferation, study shows

Scientists discover link between sugar metabolism and peroxisomal biogenesis disorders

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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