Genomics

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Kyoto University researchers identify specific gene as key regulator in iron uptake

Maintaining a good balance of iron in the body is necessary for health: too little can lead to anemia, but too much can cause debilitating disorders such as hemochromatosis.

30 May 2017

Raising age limit for routine genetic testing in colorectal cancer could identify more cases of Lynch syndrome

Raising the age limit for routine genetic testing in colorectal cancer could identify more cases of families affected by Lynch syndrome, a condition that accounts for around 5% of all colon cancers, according to new research to be presented at the annual conference of the European Society of Human Genetics today (Monday).

29 May 2017

Gene editing technology can introduce hundreds of unintended mutations, study shows

As CRISPR-Cas9 starts to move into clinical trials, a new study published in Nature Methods has found that the gene-editing technology can introduce hundreds of unintended mutations into the genome.

29 May 2017

Drug treatment used for other conditions can help women combat urinary incontinence

Urinary incontinence in women is common, with almost 50% of adult women experiencing leakage at least occasionally. Genetic or heritable factors are known to contribute to half of all cases, but until now studies had failed to identify the genetic variants associated with the condition.

29 May 2017

Open-access BRCA testing for inherited breast cancer enables identification of missed carriers

Ashkenazi Jewish women are known to have a predisposition to the inherited breast cancers BRCA1 and BRCA2, but currently genetic testing in this group is limited to women affected by breast and ovarian cancers and those who are unaffected but have a family history of the disease.

27 May 2017

UNC researchers discover cascade of gene activity during journey to maturation in fruit flies

Every animal starts as a clump of cells, which over time multiply and mature into many different types of cells, tissues, and organs.

26 May 2017

Innate genetic advantage contributes to better outcomes in newborn infant girls than boys, research shows

Newborn infant girls have better outcomes than their male counterparts due to an innate genetic advantage in responding to acute infections, according to new research from RCSI.

26 May 2017

Researchers discover cardioprotective genetic variant in isolated Greek population

A genetic variant that protects the heart against cardiovascular disease has been discovered by researchers at the Wellcome Trust Sanger Institute and their collaborators.

26 May 2017

Preliminary study: Co-occurrence of COMT and BRCA 1/2 variants may reduce breast cancer incidence

Research looking at genomic data from women with a genetic risk for breast cancer, who may never develop cancer, found their cancer-free state may be related to a second genetic variation.

25 May 2017

Scientists identify key gene in 22q11.2 that contributes to genitourinary birth defects

The 22q11.2 region of human chromosome 22 is a hotspot for a variety of birth defects. Scientists learned about this region because it is deleted in about 1 in 4,000 births, causing the loss or duplication of up to 40 genes.

25 May 2017

Study finds two genetic variants linked to bicuspid aortic valve development

Researchers are working to determine why the aortic valve doesn't form correctly in patients with the most common congenital heart defect: bicuspid aortic valve.

25 May 2017

Scientists identify genetic risk factor for equine squamous cell carcinoma

Squamous cell carcinoma (SCC) is the most common cancer found in equine eyes and the second most common tumor of the horse overall. Thanks to a recent genetic study led by UC Davis, horse owners can now identify horses at risk for ocular SCC and make informed breeding decisions.

25 May 2017

Miami is key point for transmission of Zika virus to the US

Scientists at the Scripps Translational Science Institute (TSRI) have mapped the entry of the Zika virus into the US by analysing its DNA. Miami was found to be a hot spot for transmission of Zika.

25 May 2017

UCLA study characterizes brain differences between people with genetic risk for schizophrenia, autism

A UCLA study characterizes, for the first time, brain differences between people with a specific genetic risk for schizophrenia and those at risk for autism, and the findings could help explain the biological underpinnings of these neuropsychiatric disorders.

24 May 2017

Genetic sequencing reveals how Zika virus spread in the Americas

Genetic analysis of samples collected as the Zika virus (ZIKV) spread throughout the Americas after its introduction in 2013 or 2014 has shown that the virus circulated undetected for up to a year in some regions before it came to the attention of public health authorities.

24 May 2017

Genomics

Kyoto University researchers identify specific gene as key regulator in iron uptake

Raising age limit for routine genetic testing in colorectal cancer could identify more cases of Lynch syndrome

Gene editing technology can introduce hundreds of unintended mutations, study shows

Drug treatment used for other conditions can help women combat urinary incontinence

Open-access BRCA testing for inherited breast cancer enables identification of missed carriers

UNC researchers discover cascade of gene activity during journey to maturation in fruit flies

Innate genetic advantage contributes to better outcomes in newborn infant girls than boys, research shows

Researchers discover cardioprotective genetic variant in isolated Greek population

Preliminary study: Co-occurrence of COMT and BRCA 1/2 variants may reduce breast cancer incidence

Scientists identify key gene in 22q11.2 that contributes to genitourinary birth defects

Study finds two genetic variants linked to bicuspid aortic valve development

Scientists identify genetic risk factor for equine squamous cell carcinoma

Miami is key point for transmission of Zika virus to the US

UCLA study characterizes brain differences between people with genetic risk for schizophrenia, autism

Genetic sequencing reveals how Zika virus spread in the Americas

New study identifies 16 additional genetic markers linked to psoriasis

Scientists identify ten new genetic variants linked to cardiac structure and function

Study points to new pharmacologic approach to target chemo-resistant lung cancer

Researchers identify key regulator gene for formation of cardiac valves

Study shows how different genetic mutations cause acute myeloid leukemia

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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