Genomics

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Mechanically reprogrammed connective tissue cells can promote wound healing

Researchers at PSI and ETH Zurich have taken connective tissue cells that have been mechanically reprogrammed to resemble stem cells and transplanted them into damaged skin.

29 Nov 2023

Researchers introduce CRISPR-mediated genome and cancer shredding as a conceptual paradigm to treat recurrent gliomas

Researchers demonstrated clustered regularly interspersed short palindromic repeats (CRISPR)-mediated elimination of glioblastoma (GBM) cells.

29 Nov 2023

Study identifies how three novel genes cause neurodevelopmental disorders

An international study group led by researchers of Children's Hospital of Philadelphia (CHOP) have identified how three novel genes cause neurodevelopmental disorders.

28 Nov 2023

Researchers develop faster, cheaper, and more precise method for identifying bacteria

Researchers have developed a method that identifies bacteria easily, cheaply and more precisely than before.

28 Nov 2023

DNA methylation: A key player in gene expression variation and disease manifestation

Professor Asaf Hellman and his research team at the Hebrew University-Hadassah Medical School have unveiled new findings in the realm of methylation-directed regulatory networks.

27 Nov 2023

Genetic mutation in OXR1 gene linked to brain development issues

Study investigates the effects of a loss-of-function mutation in the OXR1 gene on neurodevelopment and cellular functions in the human brain. The research shows that OXR1 deficiency impairs neural differentiation, increases sensitivity to oxidative stress, and alters histone methylation, impacting brain development and potentially contributing to neurological disorders.

27 Nov 2023

Synthetic biologists develop versatile platform for targeted drug delivery

In recent years, cell and gene therapies have shown significant promise for treating cancer, cystic fibrosis, diabetes, heart disease, HIV/AIDS and other difficult-to-treat diseases.

27 Nov 2023

New CRISPR approach shows promise for treating glioblastoma

The gene-editing technology CRISPR shows early promise as a therapeutic strategy for the aggressive and difficult-to-treat brain cancer known as primary glioblastoma, according to findings of a new study from Gladstone Institutes.

27 Nov 2023

Infant face preference linked to genetics

Whether infants at five months of age look mostly at faces or non-social objects such as cars or mobile phones is largely determined by genes.

27 Nov 2023

Genome haplarithmisis sheds light on complex genetic landscape of miscarriages

A new study published in Nature Medicine reports on a chromosomal analysis of over 1,700 spontaneous early miscarriages.

27 Nov 2023

Scientists discover master regulator gene for fat storage

We all know that weight gain and weight loss are not as simple as "calories in, calories out," given that countless factors affect body weight.

27 Nov 2023

Parkinson's disease a potential pathogenetic factor for coronary artery disease and stroke, study suggests

Researchers performed a two-sample Mendelian randomization (MR) analysis to explore causal associations between Parkinson's disease (PD) and cardio-cerebrovascular diseases.

24 Nov 2023

Genome study unveils genetic ties between cannabis use disorder and lung cancer risk

A genome-wide association study in Nature Genetics reveals insights into the genetics of cannabis use disorder, highlighting its strong association with psychopathology and a causal link to lung cancer, and suggesting distinct genetic pathways from mere cannabis use.

23 Nov 2023

Breakthrough decoding of the Y chromosome revolutionizes digestive disease research

A major breakthrough in human genetics has been achieved with the complete decoding of the human Y chromosome, opening up new avenues for research into digestive diseases.

23 Nov 2023

Non-invasive genetic test for fetal DNA sequencing developed

A team of investigators from Massachusetts General Hospital (MGH), Brigham and Women's Hospital (BWH), and the Broad Institute of MIT and Harvard have developed a non-invasive genetic test that can screen the blood of pregnant individuals to survey all genes for fetal DNA sequence variants.

22 Nov 2023

New insights into genetic risk factors for early breast cancer in women of Kazakh ethnicity

A new research paper was published in Oncotarget's Volume 14 on October 4, 2023, entitled, "Determination of genetic predisposition to early breast cancer in women of Kazakh ethnicity."

22 Nov 2023

Significant genetic variations linked to cannabis use disorder identified in major global ancestries

Multi-ancestry genome-wide association study of cannabis use disorder.

22 Nov 2023

Study shows how probiotic Bifidobacteria longum can help relieve constipation

Scientists have identified the genes in the probiotic Bifidobacteria longum responsible for improving gut motility.

21 Nov 2023

AHRI partners with BGI Genomics to boost its genomics and precision medicine capabilities

On October 13, 2023, in Addis Ababa, Armauer Hansen Research Institute (AHRI) and BGI Genomics signed a Memorandum of Understanding to enhance the Institute's genomics and precision medicine capabilities.

21 Nov 2023

Experts recommend genomics for tackling antimicrobial resistance, outline key strategies for effective surveillance

The Lancet Microbe article summarizes discussions by the Surveillance and Epidemiology of Drug-resistant Infections Consortium on using genomics for antimicrobial resistance surveillance, highlighting its benefits and challenges and providing key recommendations for effective implementation.

20 Nov 2023

Genomics

Mechanically reprogrammed connective tissue cells can promote wound healing

Researchers introduce CRISPR-mediated genome and cancer shredding as a conceptual paradigm to treat recurrent gliomas

Study identifies how three novel genes cause neurodevelopmental disorders

Researchers develop faster, cheaper, and more precise method for identifying bacteria

DNA methylation: A key player in gene expression variation and disease manifestation

Genetic mutation in OXR1 gene linked to brain development issues

Synthetic biologists develop versatile platform for targeted drug delivery

New CRISPR approach shows promise for treating glioblastoma

Infant face preference linked to genetics

Genome haplarithmisis sheds light on complex genetic landscape of miscarriages

Scientists discover master regulator gene for fat storage

Parkinson's disease a potential pathogenetic factor for coronary artery disease and stroke, study suggests

Genome study unveils genetic ties between cannabis use disorder and lung cancer risk

Breakthrough decoding of the Y chromosome revolutionizes digestive disease research

Non-invasive genetic test for fetal DNA sequencing developed

New insights into genetic risk factors for early breast cancer in women of Kazakh ethnicity

Significant genetic variations linked to cannabis use disorder identified in major global ancestries

Study shows how probiotic Bifidobacteria longum can help relieve constipation

AHRI partners with BGI Genomics to boost its genomics and precision medicine capabilities

Experts recommend genomics for tackling antimicrobial resistance, outline key strategies for effective surveillance

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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