Genomics

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Genetics and sedimentology combined to refine cyanobacteria biomarker diagnostics

Cyanobacteria are a key species in Earth's history, as they introduced atmospheric oxygen for the first time. The analysis of their evolution therefore provides important insights into the formation of modern aerobic ecosystems.

27 Oct 2023

Common chemical label shields proteins from degradation

Researchers from the University of Bergen (UiB) have uncovered that proteins use a common chemical label as a shield to protect them from degradation, which in turn affects motility and aging.

27 Oct 2023

Novel replacement strategy holds promise for the treatment of various genetic disorders

Severe Combined Immunodeficiencies (SCIDs) are a group of debilitating primary immunodeficiency disorders, primarily caused by genetic mutations that disrupt T-cell development. SCID can also affect B-cell and natural killer cell function and counts.

27 Oct 2023

Is retroelement-based gene editing a safer alternative to CRISPR-Cas approaches?

In a Perspective, Stephen Tang and Samuel Sternberg discuss retroelement-based gene editing as a safer alternative to CRISPR-Cas approaches.

26 Oct 2023

UCD professor wins ERC Synergy grant to unlock the secrets to healthy aging

Do bats hold the secret to health and longevity? A team led by Professor Emma Teeling, Full Professor of Zoology at University College Dublin (UCD), has won a prestigious European Research Council (ERC) Synergy grant of almost €12 million, to explore this fascinating question.

26 Oct 2023

Endometriosis and irritable bowel syndrome share genetic risk factors, UQ research shows

University of Queensland researchers have shown that endometriosis and irritable bowel syndrome (IBS) share genetic risk factors, explaining why patients with one condition may also have the other.

26 Oct 2023

Somatic mutations in the skin not responsible for the start or spread of psoriasis

Psoriasis -; a chronic skin condition -; is not caused or spread by spontaneous genetic mutations in the skin, new research suggests.

26 Oct 2023

New software tool provides a way for safer design of genome editing

A team of researchers has developed a software tool called DANGER (Deleterious and ANticipatable Guides Evaluated by RNA-sequencing) analysis that provides a way for the safer design of genome editing in all organisms with a transcriptome.

24 Oct 2023

Gene therapy breakthrough: Scientists develop method to deliver larger genes to target cells

Gene therapy currently represents the most promising approach for the treatment of hereditary diseases. Yet despite significant breakthroughs in recent years, there are still a number of hurdles that hinder the wider application of gene therapies.

24 Oct 2023

Study reveals an alternate origin of brain mosaicism in some children with focal epilepsy

In most people, every cell in their body contains the same genetic information. However, sometimes people can have two or more genetically different sets of cells.

24 Oct 2023

Revolutionary approach links protein analysis and single-cell study to uncover disease mechanisms

Integrated liquid-biopsy proteomics with single-cell transcriptomics from ocular cell types.

24 Oct 2023

Genomic surveillance could help detect and slow the spread of deadly 'superbugs'

Harnessing new advances in genomic surveillance technology could help detect the rise of deadly 'superbugs' and slow their evolution and spread, improving global health outcomes, a new Australian study suggests.

24 Oct 2023

Cockroaches provide clues to understanding immune system during pregnancy

Researchers are studying the dramatic physical transformation that some insects undergo to give birth to live young.

20 Oct 2023

Are ecological and evolutionary shifts in highly pathogenic avian influenza pointing to another pandemic threat?

Researchers report significant changes in the ecology and evolution of highly pathogenic avian influenza H5 viruses.

20 Oct 2023

Plant geneticists explore predictability of natural and CRISPR mutations

For tens of thousands of years, evolution shaped tomatoes through natural mutations. Then, humans came along. For centuries, we've bred and cherry-picked tomatoes with our preferred traits.

19 Oct 2023

Study sheds light on genetic architecture of postpartum depression

Postpartum depression (PPD), a common subtype of major depressive disorder, is more heritable than other psychiatric conditions, yet the genetics of PPD are understudied compared to these other psychiatric conditions., such as anxiety and bipolar disorder.

19 Oct 2023

Research reveals new way viruses suppress the CRISPR-Cas immune systems of bacteria

A microscopic discovery will not only enable scientists to understand the microbial world around us but could also provide a new way to control CRISPR-Cas biotechnologies.

18 Oct 2023

Greenspace exposure has positive impact on telomere length, study finds

A new study finds that greenspace – the vegetation in a neighborhood's yards, parks and public spaces – has a positive impact on a key genetic marker associated with exposure to stress.

18 Oct 2023

Bats' genes hold secrets to stronger immunity and longer life

Bats have acquired remarkable traits throughout their evolution. They're the only mammals that can fly, and they live much longer than other animals their size.

16 Oct 2023

Antibiotic-resistant bacteria in Ghana confined to clinical settings

Calland, J. K., et al. (2023). Population structure and antimicrobial resistance among Klebsiella isolates sampled from human, animal, and environmental sources in Ghana: a cross-sectional genomic One Health study. The Lancet Microbe. doi.org/10.1016/S2666-5247(23)00208-2.

16 Oct 2023

Genomics

Genetics and sedimentology combined to refine cyanobacteria biomarker diagnostics

Common chemical label shields proteins from degradation

Novel replacement strategy holds promise for the treatment of various genetic disorders

Is retroelement-based gene editing a safer alternative to CRISPR-Cas approaches?

UCD professor wins ERC Synergy grant to unlock the secrets to healthy aging

Endometriosis and irritable bowel syndrome share genetic risk factors, UQ research shows

Somatic mutations in the skin not responsible for the start or spread of psoriasis

New software tool provides a way for safer design of genome editing

Gene therapy breakthrough: Scientists develop method to deliver larger genes to target cells

Study reveals an alternate origin of brain mosaicism in some children with focal epilepsy

Revolutionary approach links protein analysis and single-cell study to uncover disease mechanisms

Genomic surveillance could help detect and slow the spread of deadly 'superbugs'

Cockroaches provide clues to understanding immune system during pregnancy

Are ecological and evolutionary shifts in highly pathogenic avian influenza pointing to another pandemic threat?

Plant geneticists explore predictability of natural and CRISPR mutations

Study sheds light on genetic architecture of postpartum depression

Research reveals new way viruses suppress the CRISPR-Cas immune systems of bacteria

Greenspace exposure has positive impact on telomere length, study finds

Bats' genes hold secrets to stronger immunity and longer life

Antibiotic-resistant bacteria in Ghana confined to clinical settings

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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