Genomics

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Heat-damaged DNA in food may contribute to genetic risks

Researchers have newly discovered a surprising and potentially significant reason why eating foods frequently cooked at high temperatures, such as red meat and deep-fried fare, elevates cancer risk. The alleged culprit: DNA within the food that's been damaged by the cooking process.

13 Jun 2023

New process for creating a “meta-cell overcomes the challenges of studying single-cell secrets

University of California, Irvine neuroscientists probing the gene changes behind Alzheimer's disease have developed a process of making a "meta-cell" that overcomes the challenges of studying a single cell.

13 Jun 2023

Study shows link between death perception and reduced aging in flies

Researchers led by Christi Gendron at the University of Michigan, US, have found the link between death perception and reduced aging in flies.

13 Jun 2023

DYRK1A gene may dictate susceptibility to multiple highly pathogenic coronaviruses

Entry of the SARS-CoV-2 virus into human tissues depends on the activity of a host gene that regulates production of a key viral receptor, according to a study publishing June 13th in the open access journal PLOS Biology by Madison Strine and Craig Wilen of Yale University, US, and colleagues.

13 Jun 2023

Tracing the ancestry of hybrids using a new method

If you've ever kept a garden, you're probably familiar with hybrids, from disease-resistant tomatoes to Stargazer lilies.

13 Jun 2023

ACMG publishes updated recommendations for CFTR carrier screening

The American College of Medical Genetics and Genomics (ACMG) has released updated recommendations for CFTR carrier screening –Updated recommendations for CFTR carrier screening: A position statement of the American College of Medical Genetics and Genomics.

13 Jun 2023

"Homing gene drive system" could help suppress agricultural pests

Researchers have developed a "homing gene drive system" based on CRISPR/Cas9 that could be used to suppress populations of Drosophila suzukii vinegar flies – so-called "spotted-wing Drosophila" that devastate soft-skinned fruit in North America, Europe and parts of South America – according to new research from North Carolina State University.

12 Jun 2023

Researchers identify microRNAs associated with a weakened immune response to COVID-19

A team of researchers at NYU Abu Dhabi, led by Associate Professor of Biology Youssef Idaghdour and working in collaboration with clinicians at several Abu Dhabi hospitals, investigated the association between microRNAs, a class of small RNA molecules that regulate genes, and COVID-19 severity among 259 unvaccinated COVID-19 patients living in Abu Dhabi.

11 Jun 2023

Genetic counselling for familial colorectal cancer provides improves patients' feelings of empowerment

Genetic counselling is essential when dealing with individuals who are affected by, or at risk of, inherited disease.

11 Jun 2023

Study unveils potential early detection algorithm for neurodegeneration in rare genetic disorder

Xeroderma pigmentosum (XP) is a rare and devastating genetic disorder characterised by an inability to repair skin damage caused by ultraviolet (UV) light.

11 Jun 2023

Common genetic factors could be used to identify individuals at high risk of developing colorectal cancer

Rates of colorectal cancer are high despite widespread adoption of screening programs in many high-income European countries.

11 Jun 2023

AI system in eye scans enables better diagnosis of inherited retinal diseases

Inherited retinal diseases (IRDs), single-gene disorders affecting the retina, are very difficult to diagnose since they are uncommon and involve changes in one of many candidate genes.

9 Jun 2023

Combining blood biomarkers with genomics could provide useful information about disease risk

Being to identify people at high risk of chronic disease means that they can be targeted with prevention measures before they become sick.

9 Jun 2023

ABCC9 gene variants influence the pitch of voices

In a paper published today in Science Advances, an international team led by deCODE genetics, a subsidiary of Amgen, reveals the discovery of sequence variants in the gene ABCC9 that influence the pitch of voices.

9 Jun 2023

Study uncovers novel mechanisms underlying plant immunity against major root disease

Researchers led by CHEN Yuhang and ZHOU Jianmin from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences have shown how plants resist clubroot, a major root disease that threatens the productivity of Brassica crops such as rape.

8 Jun 2023

Scientists identify the IL-17 protein as a determining factor in skin aging

A team of scientists from the Institute for Research in Biomedicine (IRB Barcelona) in collaboration with the National Center for Genomic Analysis (CNAG) has discovered that IL-17 protein plays a central role in skin aging.

8 Jun 2023

Newborn genome sequencing project identifies unanticipated disease risks

Genomic sequencing of newborns reveals unanticipated genetic risks, prompting actionable medical interventions and potential life-saving care for infants and their families. This study highlights the value of comprehensive sequencing in newborns for early detection and management of genetic conditions.

7 Jun 2023

Genomics

Heat-damaged DNA in food may contribute to genetic risks

New process for creating a “meta-cell overcomes the challenges of studying single-cell secrets

Study shows link between death perception and reduced aging in flies

DYRK1A gene may dictate susceptibility to multiple highly pathogenic coronaviruses

Tracing the ancestry of hybrids using a new method

ACMG publishes updated recommendations for CFTR carrier screening

"Homing gene drive system" could help suppress agricultural pests

Researchers identify microRNAs associated with a weakened immune response to COVID-19

Genetic counselling for familial colorectal cancer provides improves patients' feelings of empowerment

Study unveils potential early detection algorithm for neurodegeneration in rare genetic disorder

Common genetic factors could be used to identify individuals at high risk of developing colorectal cancer

AI system in eye scans enables better diagnosis of inherited retinal diseases

Combining blood biomarkers with genomics could provide useful information about disease risk

ABCC9 gene variants influence the pitch of voices

Study uncovers novel mechanisms underlying plant immunity against major root disease

Scientists identify the IL-17 protein as a determining factor in skin aging

Newborn genome sequencing project identifies unanticipated disease risks

Ancient, virus-like protein may contribute to ALS

Gene drive technology could help eradicate malaria

Researchers characterize the expression of cardiac proteins during embryonic heart development

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