Genomics

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Automata LINQ; Unlocking open, integrated lab automation

In this interview, we speak to Mostafa ElSayed, CEO of Automata, about their new, accessible, lab automation platform Automata Labs and its benefits for scientific research.

From Automata 16 Mar 2023

Scientists develop genetically defined mouse models for multiple myeloma subtypes

A team of scientists led by Martin Janz and Klaus Rajewsky at the Max Delbrück Center has successfully generated genetically defined mouse models for two subtypes of multiple myeloma.

16 Mar 2023

Scientists discover mechanism used by cancer cells to repair DNA damage induced by radiotherapy

A team of scientists led by Dr. Kei-ichi TAKATA from the Center for Genomic Integrity within the Institute for Basic Science (IBS), has discovered a new type of DNA repair mechanism that cancer cells use to recover from next-generation cancer radiation therapy.

16 Mar 2023

Study provides strong support for AAV.NT-3 gene therapy in the management of sarcopenia

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 5, entitled, "AAV1.NT-3 gene therapy prevents age-related sarcopenia."

16 Mar 2023

Researchers uncover new clue as to how "whole genome doubling" drives cancer

A single cell contains 2-3 meters of DNA, meaning that the only way to store it is to package it into tight coils.

15 Mar 2023

‘Glow-in-the-dark’ proteins could make disease diagnosis quicker and easier

Despite recent advancements, many highly sensitive diagnostic tests for viral diseases still require complicated techniques to prepare a sample or interpret a result, making them impractical for point-of-care settings or areas with few resources.

15 Mar 2023

Researchers design a virus-resistant, more useful E. coli bacteria

In a step forward for genetic engineering and synthetic biology, researchers have modified a strain of Escherichia coli bacteria to be immune to natural viral infections while also minimizing the potential for the bacteria or their modified genes to escape into the wild.

15 Mar 2023

A convergent coexpression approach identifies novel genes associated with autism

The current study analyzes transcriptional convergence across many autism risk genes.

14 Mar 2023

Study identifies link between oral and gut microbiomes and depression

Researchers investigate the role of the oral-gut-brain axis in anxiety and depression.

14 Mar 2023

New genetic animal model may inform potential therapeutic options for Down syndrome

National Institutes of Health researchers compared a new genetic animal model of Down syndrome to the standard model and found the updated version to be more similar to the changes seen in humans.

14 Mar 2023

Study shows SARS-CoV-2 causes DNA damage and elicits an altered DNA damage response

Researchers assessed the association between SARS-CoV-2 infection and DNA damage and cellular senescence.

14 Mar 2023

Hyperinflammation triggers long COVID headaches

Researchers characterize the immunological and metabolic alterations involved in chronic headache onset during post-acute sequelae of COVID-19.

13 Mar 2023

Study reveals the shared genetic basis for endometriosis and other pain conditions

University of Queensland researchers have contributed to the largest ever genetic study of endometriosis, finding new data about the variants that increase risk of the disease.

13 Mar 2023

Schizophrenia risk conferred by rare damaging genetic variants is conserved across ethnicities

Researchers have identified two previously unknown genes linked to schizophrenia and newly implicated a third gene as carrying risk for both schizophrenia and autism.

13 Mar 2023

TbID-based proteomic profiling in meiotic cells helps identify proximate proteins in A. thaliana

During meiosis, reshuffling of genetic information between homologous chromosomes through meiotic recombination creates variable gametes and hence genetic variation in offsprings.

13 Mar 2023

High-throughput genetic screening approach to study antibiotic proteins made by bacteriophages

As conventional antibiotics continue to lose effectiveness against evolving pathogens, scientists are keen to employ the bacteria-killing techniques perfected by bacteriophages, the viruses that infect bacteria.

13 Mar 2023

New study focuses on genetic diversity of E. coli bacteria in hospitalized patients

The human intestine is an environment inhabited by many bacteria and other microorganisms collectively known as the gut microbiome, gut microbiota or intestinal flora. In most people, it contributes to wellness.

13 Mar 2023

Using convolutional neural network to automate the identification of chromatid cohesion defects

Scientists from Tokyo Metropolitan University have used machine learning to automate the identification of defects in sister chromatid cohesion.

13 Mar 2023

New tool allows researchers to perform genetic screens of cell-cell interactions

Inflammatory neurological diseases, such as multiple sclerosis (MS), can arise when cell-to-cell communication between cells in the central nervous system (CNS) goes awry.

13 Mar 2023

Study highlights poor clinical utility of germline testing in cancer patients of African ancestry

New research in the March 2023 issue of JNCCN-; Journal of the National Comprehensive Cancer Network highlights how the lack of genomic research for people with African ancestry, particularly those from the Sub-Saharan region, is hampering efforts to reduce disparities for people with cancer.

10 Mar 2023

Genomics

Automata LINQ; Unlocking open, integrated lab automation

Scientists develop genetically defined mouse models for multiple myeloma subtypes

Scientists discover mechanism used by cancer cells to repair DNA damage induced by radiotherapy

Study provides strong support for AAV.NT-3 gene therapy in the management of sarcopenia

Researchers uncover new clue as to how "whole genome doubling" drives cancer

‘Glow-in-the-dark’ proteins could make disease diagnosis quicker and easier

Researchers design a virus-resistant, more useful E. coli bacteria

A convergent coexpression approach identifies novel genes associated with autism

Study identifies link between oral and gut microbiomes and depression

New genetic animal model may inform potential therapeutic options for Down syndrome

Study shows SARS-CoV-2 causes DNA damage and elicits an altered DNA damage response

Hyperinflammation triggers long COVID headaches

Study reveals the shared genetic basis for endometriosis and other pain conditions

Schizophrenia risk conferred by rare damaging genetic variants is conserved across ethnicities

TbID-based proteomic profiling in meiotic cells helps identify proximate proteins in A. thaliana

High-throughput genetic screening approach to study antibiotic proteins made by bacteriophages

New study focuses on genetic diversity of E. coli bacteria in hospitalized patients

Using convolutional neural network to automate the identification of chromatid cohesion defects

New tool allows researchers to perform genetic screens of cell-cell interactions

Study highlights poor clinical utility of germline testing in cancer patients of African ancestry

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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