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Targeting ferroptosis for overcoming chemoresistance in digestive tract tumors

The global burden of digestive tract tumors is profound, with these cancers accounting for nearly half of all malignant tumors worldwide.

8 Nov 2024

Advances in the surgical management of gastroschisis

Gastroschisis, a congenital abdominal wall defect, has transformed from a uniformly fatal condition to one with a 95% survival rate through surgical advancements over the past six decades.

8 Nov 2024

Exploring mouse models for studying liver fibrosis regression

Liver fibrosis is a progressive and potentially reversible condition that results from chronic liver damage, which can be caused by a variety of factors, including metabolic dysfunction-associated steatotic liver disease (MASLD), alcohol abuse, and viral hepatitis.

8 Nov 2024

Traditional Chinese herb shows promise against Alzheimer’s and Parkinson’s

Zizyphi spinosi semen demonstrates neuroprotective effects, improving cognitive function and reducing amyloid and tau pathology in models of aging and dementia.

8 Nov 2024

Gut bacteria changes may foreshadow rheumatoid arthritis

Changes in the gut microbiome before rheumatoid arthritis is developed could provide a window of opportunity for preventative treatments, new research suggests.

8 Nov 2024

Work-related stress linked to poor cardiovascular health

Research shows work-related stress negatively affects cardiovascular health, with implications for health behaviors and outcomes in diverse adult populations.

8 Nov 2024

Pregnancy vitamin D supplementation boosts bone density in kids up to age 7

Research indicates that vitamin D supplementation during pregnancy positively impacts children's bone health and lean mass, with potential long-term benefits.

8 Nov 2024

Age, education, and religion impact depression risk among Nigerian older adults

Research shows loneliness and physical inactivity are key factors in depression among Nigeria's older adults, emphasizing the importance of social interactions.

8 Nov 2024

Understanding metabolic alterations and immune dysfunction in acute-on-chronic liver failure

Acute-on-chronic liver failure (ACLF) is a life-threatening condition characterized by acute deterioration of liver function in patients with pre-existing chronic liver disease.

8 Nov 2024

AI and imaging technologies transform pancreatic cancer diagnostics

Pancreatic cancer (PC) presents substantial diagnostic challenges due to its aggressive nature and lack of early symptoms, leading to late detection and poor prognosis.

8 Nov 2024

New approach to COPD focuses on socioeconomic factors and comorbidities

Health care providers treating people with COPD also need to focus on the person's socioeconomic factors, along with considering their additional health conditions or comorbidities, according to a new article.

7 Nov 2024

Adipo Therapeutics shares results of studies on potential obesity treatment

Adipo Therapeutics LLC, a late-stage, preclinical biopharmaceutical company developing a potential treatment for obesity and related metabolic disorders, presented data from two studies at the annual meeting of The Obesity Society in San Antonio.

7 Nov 2024

New robotic system could revolutionize treatment of multi-site conditions

Multiple disease sites are common in clinical practice. In the brain for instance, blocked blood vessels can cause strokes, in which the lack of oxygen rapidly damages brain cells.

7 Nov 2024

New imaging technique enhances tumor and nerve visualization in HNSCC surgery

Head and neck squamous cell carcinoma (HNSCC) ranks as one of the most common cancers globally, with over 650,000 new cases reported each year.

7 Nov 2024

New biomarker could predict response to IBD treatment

Not everyone responds equally well to treatments for inflammatory bowel disease (IBD). What will work for individual patients involves trial and error during the treatment process.

7 Nov 2024

Metabolic surgery cuts diuretic dependence in heart failure patients

Pennington Biomedical Research Center researchers at the Metamor Institute, along with colleagues from Our Lady of the Lake and LSU Health-New Orleans, have recently determined that metabolic surgery on patients with heart failure can result in a reduction in the need for oral diuretics, which are used to manage symptoms such as venous and vascular pressures.

7 Nov 2024

Study finds high hepatitis C rates among opioid overdose patients

New research from the University of Missouri School of Medicine indicates that accidental opioid overdose patients in central Missouri have high rates of hepatitis C infections, despite only 40% of patients having a history of testing.

7 Nov 2024

Copper accumulation linked to aggressive growth of kidney cancer

A new study led by University of Cincinnati Cancer Center researchers details how the accumulation of copper helps clear cell renal cell carcinoma (ccRCC) -; the most common kidney cancer -; grow and advance in stage.

7 Nov 2024

C-Path announces important leadership appointments in neurology and Alzheimer's research

Critical Path Institute (C-Path) today announced key leadership appointments: Diane Stephenson, Ph.D., has been promoted to Vice President of Neurology, and Nadine Tatton, Ph.D., has been welcomed as the new Executive Director of C-Path's Critical Path for Alzheimer's Disease (CPAD) Consortium.

7 Nov 2024

Targeting CD47 protein could improve colorectal cancer treatment

A new study from the USC Norris Comprehensive Cancer Center has found evidence that targeting CD47, a protein that is part of the innate immune system, could be a key step in fighting colorectal cancer.

7 Nov 2024