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Discovery of vascular-associated fibroblastic cells opens new path for diabetes treatment

Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks the cells that produce insulin-a critical hormone that regulates blood sugar in the body.

8 Oct 2025

Researchers identify four distinct profiles of Nonverbal Learning Disability

A study published in JAMA Network Open identifies four distinct profiles of Nonverbal Learning Disability (NVLD), providing evidence that may help refine diagnostic criteria and guide more individualized approaches to care for children and families.

8 Oct 2025

Common painkiller and antidepressant combo may increase seizure risk in older adults

When older adults living in nursing homes are prescribed the pain medicine tramadol alongside certain antidepressants, their risk of seizures may go up, according to a study published October 8, 2025, in Neurology, the medical journal of the American Academy of Neurology.

8 Oct 2025

New drug candidates show promise for restoring myelin in MS

Multiple sclerosis, or MS, is a chronic autoimmune disease affecting more than 2.9 million people worldwide.

8 Oct 2025

Psychodynamic research sheds light on the roots of personality disorders

How can we explain the erratic, reckless, or even aggressive behavior of certain people in the public spotlight? An international research team consisting of members from Freie Universität Berlin, Psychologische Hochschule Berlin, and University Psychiatric Clinics Basel has investigated the specific psychodynamic mechanisms constituting the distinguishing features of personality disorders.

8 Oct 2025

Nasal spray of gold nanoparticles delivers lithium directly to the brain

In the form of a 'nasal spray', tiny gold particles act as carriers, delivering a treatment directly to the brain: developed by scientists at the Università Cattolica Rome campus/Fondazione Policlinico Universitario A. Gemelli IRCCS, a new nanotechnological device for the treatment and prevention of neuropsychiatric and neurodegenerative diseases.

8 Oct 2025

Housing support programs tied to improved cancer detection among seniors

A new study led by researchers from the Johns Hopkins Bloomberg School of Public Health found that older adults receiving federal housing assistance were on average diagnosed at earlier stages with three common cancers-colon, breast, and non-small cell lung-compared to peer cancer patients who were not receiving assistance.

8 Oct 2025

UCSF team uncovers breakthrough immunotherapy for colon cancer liver metastases

Advanced colon cancer is the leading cause of cancer-related death in young American men and the second highest worldwide. In the majority of these patients, as the cancer advances it metastasizes to the liver.

8 Oct 2025

Repeated sampling offers insight into glioblastoma therapy response

A multi-institutional study from the Accelerating GBM Therapies Through Serial Biopsies TeamLab, led by investigators from the Mass General Brigham Cancer Institute, found that serially testing tumor samples can help detect when a cancer treatment is activating the immune system in recurrent glioblastoma (GBM), even when traditional imaging measures cannot.

8 Oct 2025

Nanomedicine emerges as a key tool to boost cancer immunotherapy

Scientists at the Fralin Biomedical Research Institute at VTC and their collaborators are exploring emerging trends in cancer immunotherapy, with back-to-back review articles published in Nature Cancer and Trends in Cancer that look at how nanotechnology could reprogram the immune system and help overcome tumors' defenses.

8 Oct 2025

Kennesaw State researcher explores how hormones influence cancer development

Joanna Wardwell-Ozgo figures to work backward when determining the causes of cancer.

8 Oct 2025

Refined DNA sequencing tool reveals hidden mutations behind aging and cancer

Researchers have refined a powerful DNA sequencing tool that can uncover hidden mutations that occur naturally in our bodies as we age.

8 Oct 2025

Smoking and sex found to shape early cellular changes linked to bladder cancer

Bladder cancer is one of the most common cancers worldwide. Men are around four times more likely to develop it than women, and smoking is the main known environmental risk factor.

8 Oct 2025

New brain circuit discovery offers hope for chronic pain relief

Acute or short-lived pain, despite its bad reputation, is usually a lifesaver. It acts as a transient negative sensory experience that helps us avoid danger.

8 Oct 2025

Inappropriate triage prolongs time to pain medication in vaso-occlusive crisis

Most individuals living with sickle cell disease who presented to the emergency department with a pain crisis, known as vaso-occlusive crisis (VOC), were not triaged appropriately according to established national guidelines, reveals a study published today in Blood Advances.

8 Oct 2025

Largest study of African American brain tissue reveals key Alzheimer gene activity

The prevalence of Alzheimer disease (AD) is approximately two times higher in African Americans (AA) compared to White/European-ancestry (EA) individuals living in the U.S.

8 Oct 2025

Ireland launches next phase of national precision oncology program

Today (8th October), Ireland's Minister for Further and Higher Education, Research, Innovation and Science, James Lawless TD, launched Phase 2 of the country's leading and largest ever cancer research program, Precision Oncology Ireland (POI).

8 Oct 2025

Japan's registry transforms outcomes for infants with biliary atresia

Biliary atresia (BA) is the leading cause of liver failure in infants, marked by progressive destruction of the bile ducts. Until the late 1950s, the disease was universally fatal, with no effective treatments. The development of the Kasai portoenterostomy brought new hope, but outcomes varied widely, and many patients still required liver transplantation (LTx).

8 Oct 2025

X-HiDE project advances toward earlier detection and precision treatment of inflammatory diseases

Facilitating earlier diagnosis and more precise treatment for patients with inflammatory diseases. This is the goal as the X-HiDE research project at örebro University in Sweden now enters its next phase, in collaboration with eleven companies and four other universities in Europe and the USA.

8 Oct 2025

Engineered Salmonella therapy delivers immune payloads to combat cancer

A new research paper was published in Volume 16 of Oncotarget on October 6, 2025, titled "ACTM-838, a novel systemically delivered bacterial immunotherapy that enriches in solid tumors and delivers IL-15/IL-15Rα and STING payloads to engage innate and adaptive immunity in the TME and enable a durable anti-tumor immune response."

8 Oct 2025