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New TIL therapy improves treatment's effectiveness in patients with metastatic gastrointestinal cancers

A new form of tumor infiltrating lymphocyte (TIL) therapy, a form of personalized cancer immunotherapy, dramatically improved the treatment's effectiveness in patients with metastatic gastrointestinal cancers, according to results of a clinical trial led by researchers at the National Institutes of Health (NIH).

1 Apr 2025

New tool helps predict CAR T therapy outcomes for lymphoma patients

Researchers with City of Hope, one of the largest and most advanced cancer research and treatment organizations in the United States, with its National Medical Center in Los Angeles ranked among the nation's top 5 cancer centers by U.S. News & World Report, and MSK have created a tool that uses machine learning to assess a non-Hodgkin lymphoma (NHL) patient's likely response to chimeric antigen receptor (CAR) T cell therapy before starting the treatment, according to study results published today in Nature Medicine.

1 Apr 2025

A new blood test could improve how Alzheimer’s disease is diagnosed

The blood test for eMTBR-tau243 shows strong correlation with tau pathology, enhancing Alzheimer's diagnosis and monitoring cognitive decline effectively.

1 Apr 2025

Vitamin D monitoring during pregnancy and postpartum

Researchers determine the impact of vitamin D levels during pregnancy and their role in maternal and infant health outcomes.

1 Apr 2025

Study finds clues to hypertension hidden in electronic health records

A new study from investigators at Mass General Brigham shows that clues about hypertension may be buried in electronic health records (EHR).

1 Apr 2025

Mayo Clinic launches study to investigate rapidly progressive dementia in Alzheimer's

Most patients with Alzheimer's disease and Alzheimer's Disease Related Dementias (ADRD) experience the gradual onset and progression of cognitive symptoms, leading to decline over years or decades.

1 Apr 2025

Study: Mental health providers often miss bulimia diagnosis

When presented with a vignette describing the behaviors and characteristics of a patient with disordered eating, only a quarter of mental health providers who participated in a new study were able to correctly diagnose bulimia nervosa.

1 Apr 2025

Queen Mary scientists invent a new way to repair osteochondral defects

Scientists at Queen Mary University of London have invented a new way to repair osteochondral defects – a common form of joint damage often caused by sports injuries or trauma – and to prevent progression to osteoarthritis.

1 Apr 2025

Patient navigators boost follow-up colonoscopies and reduce delays

A University of Arizona Health Sciences-led study found that patients are more likely to get colonoscopies following abnormal stool test results if patient navigators assist them through the process.

31 Mar 2025

ALL ALS Consortium creates a central information hub to accelerate ALS research

The Access for All in ALS (ALL ALS) Consortium announced the launch of its official website, creating a central hub for information about its initiatives and clinical research studies. ALL-ALS.org is designed to inform and engage researchers, clinicians, and current and prospective study participants.

31 Mar 2025

Tirzepatide improves kidney, cardiovascular function in patients with obesity and HFpEF

The drug tirzepatide improved kidney function and cardiovascular outcomes among patients with obesity and heart failure with preserved ejection fraction (HFpEF) compared with placebo at one year, according to featured clinical research presented at the American College of Cardiology's Annual Scientific Session (ACC.25) and simultaneously published in JACC.

31 Mar 2025

Study helps characterize how sleep deficiency may relate to Alzheimer's pathogenesis

New research reveals that lower proportions of specific sleep stages are associated with reduced brain volume in regions vulnerable to the development of Alzheimer's disease over time.

31 Mar 2025

Five lifestyle changes by 50 can add a decade to your life, global study finds

Study estimates the global lifetime risk and benefits of modifying cardiovascular risk factors like hypertension, smoking, and obesity by age 50, showing significant improvements in both life expectancy and quality of life. It highlights the importance of early intervention and midlife changes in preventing cardiovascular disease and mortality.

31 Mar 2025

New AI voice screening method improves detection of anxiety and depression

Scientists at the National Center for Supercomputing Applications and the University of Illinois College of Medicine Peoria (UICOMP) were authors of a research paper published in the Journal of Acoustical Society of America Express Letters that demonstrates improved, automated screening methods for anxiety and major depressive disorders.

31 Mar 2025

New genetic discovery sheds light on PHTS-related vascular malformations

During development, cells grow, expand, and migrate to generate tissues and organs in a highly controlled manner.

31 Mar 2025

New virtual reality system aims to revolutionize psychiatric diagnosis

Researchers have developed a virtual reality-based system that shows promise in improving the differentiation between common mental health conditions, potentially paving the way for earlier and more personalized treatment.

31 Mar 2025

Blood test offers insight into Alzheimer's stage and severity

A newly developed blood test for Alzheimer's disease not only aids in the diagnosis of the neurodegenerative condition but also indicates how far it has progressed, according to a study by researchers at Washington University School of Medicine in St. Louis and Lund University in Sweden.

31 Mar 2025

Swedish researchers identify genetic variants linked to atherosclerosis

Swedish researchers have identified genetic variants that increase the risk of atherosclerosis. The aim is for these new findings to enable earlier detection of atherosclerosis and improved treatment of cardiovascular diseases such as heart attack and stroke.

31 Mar 2025

Speech neuroprosthesis unlocks near-real-time communication for patients with paralysis

Marking a breakthrough in the field of brain-computer interfaces (BCIs), a team of researchers from UC Berkeley and UC San Francisco has unlocked a way to restore naturalistic speech for people with severe paralysis.

31 Mar 2025

Fluid restriction does not improve health in heart failure patients

People with heart failure have long been advised to limit the amount of fluids they consume each day to help reduce congestion, or the buildup of fluid in the lungs and extremities, but that advice provides no benefit, according to a study presented at the American College of Cardiology's Annual Scientific Session.

31 Mar 2025