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Curcumin compound reactivates Epstein–Barr virus, offering safer cancer therapy

A novel curcumin derivative, C210, activates the Epstein–Barr virus (EBV) lytic cycle without producing infectious virions by disrupting HSP90. This discovery opens avenues for safer EBV-positive cancer therapies.

5 Nov 2024

Binghamton University joins groundbreaking $42.8 million inflammatory disease treatment project

Binghamton University will play a key role in a federal grant of up to $42.8 million to develop an implantable device that acts as a living pharmacy to treat inflammatory diseases.

5 Nov 2024

Researchers awarded Synergy Grant to target tumor vessels and boost immunotherapy

Targeting and customizing blood vessels in tumors to increase T cell infiltration and maintain their function may represent the next breakthrough in cancer therapy.

5 Nov 2024

Traumatic brain injury should be recognized as a chronic condition, experts say

A commentary, published in the Journal of Neurotrauma, calls for traumatic brain injury to be recognized as a chronic condition as are diabetes, asthma, depression and heart failure.

5 Nov 2024

New technology for visualizing AMPA receptors offers insights into psychiatric disorders

Even though psychiatric disorders such as schizophrenia, bipolar disorder, and autism spectrum disorder (ASD) are quite common, their diagnosis and treatment are challenging.

5 Nov 2024

Simple symptom management support improves wellbeing after heart transplant

When a patient with heart failure has received a new heart and survives - the transplantation is deemed a success.

5 Nov 2024

$Herba Siegesbeckiae subfraction HS-C protects against myocardial I/R injury$

Herba Siegesbeckiae subfraction HS-C protects against myocardial I/R injury

Announcing a new publication for Acta Materia Medica journal. Herba Siegesbeckiae (HS) has been traditionally used for managing cardio- and cerebro-vascular diseases.

5 Nov 2024

Revised diagnostic criteria seek to avoid over-diagnosis of Alzheimer’s disease

Diagnosis of Alzheimer's Disease (AD) is currently largely based on the presence of biomarkers. This may lead to a problematic over-diagnosis if this is incorrectly interpreted.

5 Nov 2024

New active substance shows promise in treating acute sudden hearing loss

A research team led by MedUni Vienna has investigated AC102, a new active substance that offers hope of an effective treatment for acute sudden hearing loss. The latest results have been published in the scientific journal "Cell Death & Disease".

5 Nov 2024

Modulating CD39 expression to enhance CAR-T cell therapy against hepatocellular carcinoma

In the quest to enhance the efficacy of chimeric antigen receptor T (CAR-T) cell therapy against hepatocellular carcinoma (HCC), a recent study has identified a pivotal role for CD39 expression in modulating the function of CAR-T cells.

5 Nov 2024

Lupus Research Alliance announces 33 studies to be presented at ACR Convergence 2024

The Lupus Research Alliance (LRA), the largest private funder of lupus research worldwide, today announced that a total of 33 studies, funded by the organization or supported by its clinical research affiliate Lupus Therapeutics, will be presented at ACR Convergence 2024.

5 Nov 2024

Shaping sustainable diets: U.K. study finds that smaller portions are key to reducing meat intake

The decline in meat consumption in the UK is driven by smaller portion sizes, suggesting effective strategies for improving public health and the environment.

5 Nov 2024

Study finds regular physical activity slows biological aging in type 2 diabetes patients

Regular physical activity is crucial for slowing biological aging in type 2 diabetes, with specific thresholds identified for optimal health benefits.

5 Nov 2024

AI-powered ECG model predicts heart disease risk with precision

A new AI-enhanced ECG model, AIRE, accurately predicts mortality and heart disease risk, providing clinicians with actionable, patient-specific insights.

5 Nov 2024

New Alzheimer's guidelines focus on risk, not diagnosis, in healthy adults

Researchers from the International Working Group recommend categorizing biomarker-positive, cognitively normal individuals as "at risk" for Alzheimer's to avoid unnecessary diagnoses and emphasize preventive care.

4 Nov 2024

Education, wealth, and job type shape aging brains and cognitive health

Socioeconomic factors, including wealth, education, and occupation, significantly impact cognitive health, influencing transitions to dementia or cognitive impairment and the chance of recovery.

4 Nov 2024

How calcium and magnesium deficiencies impact cognitive health

Older hospitalized adults with both magnesium and calcium deficiencies exhibit significantly lower cognitive function, highlighting the need for nutrient monitoring in aging populations.

4 Nov 2024

New model sheds light on APOE4's role in Alzheimer's pathology

In healthy brains, immune cells called microglia patrol for damage, clearing away debris and harmful proteins. But in the presence of the APOE4 protein-;the most important genetic risk factor for Alzheimer's disease-;the same cells cause harmful inflammation and clumps of misfolded proteins, according to a new study by scientists at Gladstone Institutes.

4 Nov 2024

Researchers uncover the hidden history of concussion in sports

University of Queensland researchers have uncovered the hidden history of concussion in sport, finding the brain-trauma crisis has a long and complex past.

4 Nov 2024

Johns Hopkins study offers new hope for wet AMD patients

A new study from researchers at Wilmer Eye Institute, Johns Hopkins Medicine explains not only why some patients with wet age-related macular degeneration (or "wet" AMD) fail to have vision improvement with treatment, but also how an experimental drug could be used with existing wet AMD treatments to save vision.

4 Nov 2024