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Later-stage cancers thrive by finding detours around drug roadblocks

Later-stage cancers thrive by finding detours around roadblocks that cancer drugs put in their path, but a Purdue University biochemist is creating maps that will help drugmakers close more routes and develop better drugs.

28 Mar 2012

Invasive strategy benefits patients with myotonic dystrophy type 1 neuromuscular disorder

Patients with a cardiac irregularity and myotonic dystrophy type 1 (a severe neuromuscular disorder with a high risk of sudden death) who received an invasive treatment strategy that included testing of their heart's electrical conduction system and if needed, implantation of a device such as a pacemaker, had an associated higher rate of 9-year survival compared to patients treated noninvasively, according to a study in the March 28 issue of JAMA.

28 Mar 2012

Improper preparation for colonoscopy hides pre-cancerous polyps

What happens on the day before a colonoscopy may be just as important as the colon-screening test itself.

28 Mar 2012

Out-of-hospital use of GIK as therapy for ACS patients needs to be assessed

Patients experiencing symptoms such as chest pain who received from paramedics an intravenous solution consisting of glucose-insulin-potassium (GIK) had no reduction in the rate of progression to heart attack and no improvement in 30-day survival, although GIK was associated with a lower rate of the composite outcome of cardiac arrest or in-hospital death, according to a study appearing in JAMA.

28 Mar 2012

Lung cancers diagnosed in CT screening are similar to those found in clinical practice

Growth rates of lung cancers found by annual rounds of computed tomography (CT) screening are important for determining the usefulness and frequency of screening, as well as for determining the treatment.

28 Mar 2012

Researchers identify DNA methylation in patients with schizophrenia

In a new study, researchers at the Swedish medical university Karolinska Institutet have identified epigenetic changes - known as DNA methylation - in the blood of patients with schizophrenia.

28 Mar 2012

ACCR designates Georgetown student as early-career scientist

David A. Solomon, who will graduate from Georgetown University School of Medicine this year with M.D. and Ph.D. degrees, has been designated one of four outstanding early-career scientists by the American Association for Cancer Research (AACR) -- a highly prestigious honor. Solomon will present his work at a special symposium, Future Leaders in Basic Cancer Research, on April 2nd at the AACR Annual Meeting 2012 in Chicago.

28 Mar 2012

Imatinib improves RFS, overall survival in GIST patients after surgery

Among patients with a high risk of recurrence of a gastrointestinal stromal tumor following surgery for its removal, patients who received imatinib (a drug to treat certain cancers) for 3 years instead of 1 had improved recurrence-free survival and overall survival, according to a study in the March 28 issue of JAMA.

28 Mar 2012

Researchers to evaluate new NHS community pharmacy scheme

A new NHS community pharmacy scheme to help patients understand and get the best out of a new medicine is to be tested and evaluated by a team led by The University of Nottingham in collaboration with University College London and Warwick Business School.

28 Mar 2012

Supervisor training can curb employees' substance use and intoxication

To curb employees' on-the-job substance use and intoxication, bosses need to do more than just be around their employees all day, according to a new study from the University at Buffalo Research Institute on Addictions (RIA).

28 Mar 2012

Hyperinsulinemia itself not a cause of atherosclerosis

A number of studies have shown that excess insulin circulating in the bloodstream is a major independent risk factor for cardiovascular disease. However, a new study from Joslin Diabetes Center finds that this condition, called hyperinsulinemia, is itself not a cause of atherosclerosis.

28 Mar 2012

Research on sexuality and old age paves way for new view of masculinity

"Dirty old men" or asexual seniors? Research on sexuality and old age paves the way for a new view of masculinity.

28 Mar 2012

Heart bypass surgery appears to carry higher long-term survival rate

Patients with coronary heart disease and their doctors have long been challenged by the decision of whether to pursue bypass surgery or opt for the less-invasive percutaneous coronary intervention (PCI, which includes stenting and balloon angioplasty). New evidence reveals bypass surgery appears to carry a higher long-term survival rate, according to research presented today at the American College of Cardiology's 61st Annual Scientific Session.

28 Mar 2012

North Shore-LIJ's first-ever walking challenge kicks off this week

The North Shore-LIJ Health System's first-ever walking challenge, the Walk to Paris, kicked off this week with 15,000 employees lacing up their sneakers to compete for a free trip to Paris. The fitness challenge is one of many initiatives that the 15-hospital health system has rolled out to improve the health and wellness of its employees.

28 Mar 2012

Pulsed photoacoustic techniques can diagnose different cancer cell types

Researchers have developed multiple techniques and procedures to detect cancer cells during the earliest stages of the disease or after treatment. But one of the major limitations of these technologies is their inability to detect the presence of only a few cancer cells.

28 Mar 2012

Magnetic iron oxide nanoparticle-induced hyperthermia can kill cancer cells

Using nanoparticles and alternating magnetic fields, University of Georgia scientists have found that head and neck cancerous tumor cells in mice can be killed in half an hour without harming healthy cells.

28 Mar 2012

First clinical trial to evaluate intravenous antibiotics for CF lung infection

Experts from Bristol and Nottingham are leading a major new national study to investigate whether intravenous antibiotics are effective in killing a common germ that causes dangerous complications in cystic fibrosis (CF) patients.

28 Mar 2012

Cardiac CT more effective in evaluating ER patients with chest pain

Cardiac computed tomography angiography scans (CT scans that look at the heart) can provide a virtually instant verdict on whether chest pain is from blockage of the coronary arteries.

28 Mar 2012

Data supports links between AD and diabetes: New study

Alzheimer's disease is the sixth leading cause of death in the United States and the only cause of death among the top 10 in America without a way to prevent, cure or even slow its progression, according to the Alzheimer's Association. Today, 5.4 million Americans are living with the disease, and another American develops it every 69 seconds.

28 Mar 2012