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Comprehensive roadmap promises to improve cancer immunotherapy development

The Cancer Immunotherapy Consortium (CIC) of the Cancer Research Institute (CRI) and the Association for Cancer Immunotherapy (CIMT) have issued a joint white paper, published in the October 13 issue of Nature Biotechnology, outlining a comprehensive roadmap that promises to help improve and facilitate the path forward in the development of novel immunotherapies for cancer.

19 Oct 2011

Scientists determine structure of GAG proteoglycan

If genes provide the blueprint for life and proteins are the machines that do much of the work for cells, then carbohydrates that are linked to proteins are among the tools that enable cells to communicate with the outside world and each other. But until now, scientists have been unable to determine the structure of a biologically important so-called GAG proteoglycan-or even to agree whether these remarkably complex molecules have well-defined structures.

19 Oct 2011

FUTURAGE project to tackle Europe's ageing population over the next 10 years

An ambitious project led by researchers at the University of Sheffield is set to tackle the grand challenge of Europe's ageing population over the next 10 years.

19 Oct 2011

Medication therapy management in interprofessional heath care

Akinyele and other University of Maryland School of Pharmacy students at the Mercy Health Clinic in Gaithersburg, Md. are learning firsthand about the remarkable effectiveness of medication therapy management (MTM), a hot new pharmacy trend in interprofessional heath care.

19 Oct 2011

U of M technology may help prolong lives of people with trauma, massive blood loss

A new technology from the University of Minnesota has resulted in a startup that may help prolong the lives of victims suffering from massive blood loss or trauma. The university's Office for Technology Commercialization has signed a license agreement with Denver-based Ariel Pharmaceuticals authorizing the private company to develop and commercialize the therapy.

19 Oct 2011

Research points to ineffective and incomplete drug education as factor in heroin initiation

Researchers found Chicago area suburban heroin users have little knowledge about the drug and its effects when they first use it, and they often substitute heroin after becoming addicted to prescription pain medications.

19 Oct 2011

Oral laquinimod shows promise against multiple sclerosis

Teva Pharmaceutical Industries Ltd. and Active Biotech today announced the presentation of Phase III clinical and pre-clinical data, which collectively demonstrate that once-daily oral laquinimod modulates the pathological processes of multiple sclerosis to impact disease activity, disability progression and brain volume loss.

19 Oct 2011

Women more likely to develop lupus at earlier ages

Debilitating. Destructive. Life-altering. These are just a few words used to describe autoimmune disease. Autoimmune diseases affect women 8 times more often than men, with lupus being one of the most disruptive. Lupus is a disease that occurs when a person's immune system attacks its own tissues and organs instead of attacking foreign invaders such as common viruses and bacteria. Lupus often results in wide-spread inflammation, pain, swelling and organ/tissue damage throughout the body.

19 Oct 2011

New sequencing method can identify genetic variants linked to ASD

Geneticists at Emory University School of Medicine have demonstrated a method that enables the routine amplification of all the genes on the X chromosome. The technology allows the rapid and highly accurate sequencing and identification of novel genetic variants affecting X chromosome genes.

19 Oct 2011

Topical corticosteroids show promise against bacterial corneal ulcers

A UCSF study gives hope to those suffering from severe cases of bacterial corneal ulcers, which can lead to blindness if left untreated. The use of topical corticosteroids in a randomized controlled trial was found to be neither beneficial nor harmful in the overall patient population in the study. However, it helped patients who had more serious forms of bacterial corneal ulcers, according to UCSF researchers.

19 Oct 2011

African-Americans donate exclusively to family members for living kidney transplants

Family matters, especially when it comes to African-Americans and living kidney donation. In a study conducted at Wake Forest Baptist Medical Center, researchers found that African-Americans donate almost exclusively to family members for living kidney transplants, as compared to Caucasians.

19 Oct 2011

RetroSense, WSU sign license agreement for channelrhodopsin-based approaches

RetroSense Therapeutics, LLC, a Michigan-based company, announced that it has executed its exclusive, worldwide option and signed a license agreement for novel gene-therapy approaches for treating blindness developed at Wayne State University's School of Medicine.

19 Oct 2011

Mayo Clinic introduces heart health awareness campaign

Mayo Clinic today is launching a heart health awareness campaign featuring a parody of the 1982 hit song "867-5309/Jenny" at the third annual Social Media Summit, produced by Mayo Clinic in conjunction with Ragan Communications.

19 Oct 2011

Many overweight, obese patients do not believe their weight poses health risks

Many overweight and obese patients in hospital emergency departments don't believe their weight poses health risks, and many say doctors have never told them otherwise, according to a University of Florida study.

19 Oct 2011

Electron-beam sterilized dialysis membrane may increase risk of thrombocytopenia

Patients who had undergone hemodialysis using dialyzers that had been sterilized with the use of electron beams were more likely to develop thrombocytopenia, according to a study in the October 19 issue of JAMA.

19 Oct 2011

Young adults born prematurely show multiple biological signs of risks to future health

Young adults who were born prematurely show multiple biological signs of risks to future health, research from Imperial College London has found. The scientists, reporting their findings tomorrow in the journal Pediatric Research, say that the research indicates that urgent work is now needed to monitor preterm babies into adulthood to improve the detection of early signs of disease.

19 Oct 2011

UCSD unveils Center for the Future of Surgery

Every year, millions of patients undergo lifesaving surgeries. The outcome of each procedure is driven by dynamic factors such as the patient's health, drugs and instruments used, team communication, and the wisdom of the surgeon's hand. To advance safety and innovation in today's operating rooms, the School of Medicine at the University of California, San Diego has unveiled the Center for the Future of Surgery (CFoS) ─ the largest state-of-the art facility in the nation dedicated to catalyzing novel surgical technologies, techniques and teaching methods.

19 Oct 2011

Jersey Shore completes first procedure with Abiomed's Impella 2.5 heart pump

Jersey Shore University Medical Center announces the completion of its first procedure with Abiomed's Impella 2.5 heart pump. Jersey Shore is the first and only regional hospital to include the World's Smallest Heart Pump in their portfolio of treatment options to assist critically ill heart patients.

19 Oct 2011

Study finds why corticosteroids do not work well for COPD patients

Chronic obstructive pulmonary disease (COPD) leads to persistent inflammation of the airways and is typically managed with corticosteroids, a class of anti-inflammatory medication. However, corticosteroids do not improve survival nor alter the progression of COPD and may reduce lung symptoms as little as 20 percent.

19 Oct 2011

Subjects with borderline elevated IgE levels less likely to develop glioma

A study published online Oct. 18 in the Journal of the National Cancer Institute provides some new but qualified support for the idea that the immune system's response to allergies may reduce the risk of developing deadly brain tumors.

19 Oct 2011