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NCRM at Case Western Reserve to host stem cell conference in Cleveland

The National Center for Regenerative Medicine (NCRM) at Case Western Reserve University is proud to present "MSC 2011: Innovations in Cell-Based Regenerative Therapies," a three-day forum to highlight transformative breakthroughs in the area of adult stem cell medicine with a focus on how this research is being applied in patient care settings through innovative clinical trials.

18 Aug 2011

Clinical trials to evaluate and validate infrastructure of P-medicine consortium

Retrospective and prospective clinical trials will be run to evaluate and validate the infrastructure of the P-medicine consortium, announced a poster at the recent 3rd symposium of the Worldwide Innovative Networking in Personalized Cancer Medicine, held in Paris 6-8 July, 2011.

18 Aug 2011

Lighter smokers with two high-risk gene variations more likely to develop lung cancer

Smokers with variations in two specific genes have a greater risk of smoking more cigarettes, becoming more dependent on nicotine and developing lung cancer, a new study from the Centre for Addiction and Mental Health (CAMH) shows.

18 Aug 2011

Endo terminates collaboration and axomadol development program with Grunenthal

Endo Pharmaceuticals announced today that it is terminating its research program and collaboration related to the development of axomadol.

18 Aug 2011

EMA accepts Pfizer's regulatory submissions of two investigational cancer drugs for review

Pfizer Inc. announced today that the European Medicines Agency (EMA) has accepted Pfizer's regulatory submissions for review of two investigational compounds - crizotinib, an oral first-in-class anaplastic lymphoma kinase (ALK) inhibitor, for the treatment of patients with previously treated ALK-positive advanced non-small cell lung cancer (NSCLC); and bosutinib for the treatment of adult patients with newly diagnosed Philadelphia chromosome positive (Ph+) chronic myeloid leukemia (CML) in the chronic phase.

18 Aug 2011

Neoprobe sells gamma detection device business to Devicor

Neoprobe Corporation, a diversified developer of innovative oncology surgical and diagnostic products, announced today that it completed the previously announced sale of its neoprobe GDS line of gamma detection device systems to Devicor Medical Products, Inc. for $30 million in upfront consideration, plus up to an additional $20 million in royalties based on Devicor's achievement of certain revenue milestones.

18 Aug 2011

Ultrasound can predict high risk of stroke in patients with asymptomatic carotid stenosis

A new study shows that a simple ultrasound test may help to identify people at high risk of stroke who have a condition called asymptomatic carotid stenosis, a narrowing of the carotid artery found in the neck, in which few or no symptoms are present.

18 Aug 2011

CEL-SCI receives Chinese patent for Multikine cancer drug

CEL-SCI Corporation today announced that the Chinese patent office has issued a key patent covering CEL-SCI's investigational cancer drug, Multikine.

18 Aug 2011

New research: Sniffer dogs can reliably identify lung cancer

Sniffer dogs could be used for the early detection of lung cancer, according to new research published in the European Respiratory Journal.

18 Aug 2011

Enrollment commences in Allos' FOLOTYN Phase 3 trial for peripheral T-cell lymphoma

Allos Therapeutics, Inc. today announced the enrollment of the first patient in a Phase 3 randomized clinical trial (PDX-017) evaluating FOLOTYN in patients with previously undiagnosed peripheral T-cell lymphoma.

18 Aug 2011

Roche receives FDA approval for Zelboraf to treat BRAF mutation-positive metastatic melanoma

Genentech, a member of the Roche Group, today announced that the U.S. Food and Drug Administration (FDA) approved Zelboraf (vemurafenib) for the treatment of BRAF V600E mutation-positive, inoperable or metastatic melanoma, as determined by an FDA-approved test.

18 Aug 2011

New gout drug may help severely affected: Study

A new drug for gout could help very sick gout patients who don't get better with usual treatment, according to a new study. The research was designed and funded by the pharmaceutical company Savient, which markets the drug, called Krystexxa (pegloticase).

17 Aug 2011

Autism risk in siblings of autistic children is higher: Study

A new study reveals that parents with an autistic child have a 19% increased chance of getting another one with a similar disorder. Experts said the study, published Monday in the journal Pediatrics, is the most comprehensive of its kind and should be used to counsel families.

17 Aug 2011

Zelboraf receives FDA approval for treatment of metastatic melanoma

The U.S. Food and Drug Administration today approved Zelboraf (vemurafenib), a drug to treat patients with late-stage (metastatic) or unresectable (cannot be removed by surgery) melanoma, the most dangerous type of skin cancer.

17 Aug 2011

FDA accepts Protalix taliglucerase alfa NDA resubmission for review

Protalix BioTherapeutics, Inc., announced today that the U.S. Food & Drug Administration (FDA) has accepted for review the resubmission of the taliglucerase alfa New Drug Application (NDA) following the Company's receipt of a Complete Response Letter (CRL) in February 2011.

17 Aug 2011

Emergent commences TRU-016 Phase 1b/2 combination trial in relapsed indolent NHL

Emergent BioSolutions Inc. today announced the initiation of a Phase 1b/2 study (16011) of TRU-016 in combination with rituximab and bendamustine for patients with relapsed indolent non-Hodgkin's B-cell lymphomas, including follicular lymphoma, small lymphocytic lymphoma and marginal zone lymphoma.

17 Aug 2011

Mylan confirms Frova patent challenge

Mylan Inc. today confirmed that the company and its subsidiary Mylan Pharmaceuticals Inc. have been sued by Endo Pharmaceuticals in connection with the filing of an Abbreviated New Drug Application (ANDA) with the U.S. Food and Drug Administration (FDA) for Frovatriptan Succinate EQ, 2.5 mg base tablets.

17 Aug 2011

Researchers document how immune system can counteract advancement of Alzheimer's

For the first time a research team at Charité - Universitätsmedizin Berlin and Universitätsklinik Freiburg succeeded in documenting how the immune system can counteract the advancement of Alzheimer's disease.

17 Aug 2011

Debate emerges regarding benefit of CT scans for lung cancer

Some hospitals are offering discounted CT scans to worried smokers, leading experts to question whether it's a marketing strategy or offers some health benefit.

17 Aug 2011

Study reveals structure of ribosomal assembly intermediate

As part of a joint research effort with the University of Michigan, scientists from the Florida campus of The Scripps Research Institute have for the first time defined the structure of one of the cell's most basic engines, which is required for cell growth, as it assembles from its components.

17 Aug 2011

Medical Condition News

NCRM at Case Western Reserve to host stem cell conference in Cleveland

Clinical trials to evaluate and validate infrastructure of P-medicine consortium

Lighter smokers with two high-risk gene variations more likely to develop lung cancer

Endo terminates collaboration and axomadol development program with Grunenthal

EMA accepts Pfizer's regulatory submissions of two investigational cancer drugs for review

Neoprobe sells gamma detection device business to Devicor

Ultrasound can predict high risk of stroke in patients with asymptomatic carotid stenosis

CEL-SCI receives Chinese patent for Multikine cancer drug

New research: Sniffer dogs can reliably identify lung cancer

Enrollment commences in Allos' FOLOTYN Phase 3 trial for peripheral T-cell lymphoma

Roche receives FDA approval for Zelboraf to treat BRAF mutation-positive metastatic melanoma

New gout drug may help severely affected: Study

Autism risk in siblings of autistic children is higher: Study

Zelboraf receives FDA approval for treatment of metastatic melanoma

FDA accepts Protalix taliglucerase alfa NDA resubmission for review

Emergent commences TRU-016 Phase 1b/2 combination trial in relapsed indolent NHL

Mylan confirms Frova patent challenge

Researchers document how immune system can counteract advancement of Alzheimer's

Debate emerges regarding benefit of CT scans for lung cancer

Study reveals structure of ribosomal assembly intermediate

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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