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Pooled analysis shows finerenone reduces all-cause mortality but not cardiovascular death

A pooled analysis of three large trials failed to demonstrate significant reductions in cardiovascular death with finerenone, but significantly lower all-cause mortality, cardiovascular events and kidney outcomes were observed, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

2 Sep 2024

Study reveals key genetic markers for early onset bicuspid aortic valve complications

Genetic variants linked to a rare form of bicuspid aortic valve disease that affects young adults and can lead to dangerous and potentially life-threatening aortic complications have been identified by researchers at UTHealth Houston.

2 Sep 2024

Breakthrough in blood stem cell development offers hope for leukemia and bone marrow failure

Melbourne researchers have made a world first breakthrough into creating blood stem cells that closely resemble those in the human body. And the discovery could soon lead to personalized treatments for children with leukemia and bone marrow failure disorders.

2 Sep 2024

Study finds no added benefit of extensive ablation for persistent atrial fibrillation

In patients with persistent atrial fibrillation (AF), standard treatment with pulmonary vein isolation (PVI) ablation resulted in similar outcomes to more extensive ablation in other areas of the heart.

2 Sep 2024

Fasting before cardiac catheterization not necessary, study finds

There was no difference in complications in patients who fasted or did not fast before cardiac catheterization procedures requiring conscious sedation, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

2 Sep 2024

$Mineralocorticoid receptor antagonists benefit heart failure patients across ejection fractions$

Mineralocorticoid receptor antagonists benefit heart failure patients across ejection fractions

Mineralocorticoid receptor antagonists (MRAs) reduced the risk of cardiovascular death or heart failure (HF) hospitalization in patients with HF and reduced ejection fraction (HFrEF) and also in those with mildly reduced or preserved ejection fraction (HFmrEF/HFpEF), according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

2 Sep 2024

Cryoballoon ablation as effective as radiofrequency for atrial fibrillation in heart failure patients

Cryoballoon (CB) ablation is as effective at reducing recurrences of atrial fibrillation (AF) and atrial tachycardia (AT) at 1-year, when compared to the current most widely used technique, radiofrequency (RF) ablation, in heart failure patients with a reduced ejection fraction (HFrEF), according to late breaking research presented in a Hot Line Session at this year's ESC Congress 2024 in London, UK (30 Aug - 2 Sept).

2 Sep 2024

Catheter ablation proven effective for atrial fibrillation in new study

A catheter ablation procedure widely used to treat the most common heart rhythm disorder significantly reduces the burden of atrial fibrillation (AF) and results in clinically important improvements in symptoms and quality of life compared with a sham (placebo) procedure, according to late breaking research presented in a Hot Line Session at this year's ESC Congress 2024 in London, UK (30 Aug - 2 Sept).

2 Sep 2024

$Finerenone shows promise for heart failure with mildly reduced or preserved ejection fraction$

Finerenone shows promise for heart failure with mildly reduced or preserved ejection fraction

Finerenone reduced the composite of total first and recurrent heart failure (HF) events (hospitalizations for HF or urgent HF visits) and cardiovascular death in patients with HF and mildly reduced or preserved ejection fraction, according to an international clinical trial led by investigators from Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system.

2 Sep 2024

Study identifies key predictors of severe mpox cases

The study uncovers factors influencing mpox severity and duration, emphasizing the role of viral load and specific clinical presentations in patient outcomes.

2 Sep 2024

Recent studies underscore the importance of diet for the prevention of cancer

Recent research highlights the role of diet in cancer prevention, emphasizing Mediterranean and plant-based diets while noting risks associated with red meat.

2 Sep 2024

Research finds particulate pollution during pregnancy may impact newborn kidney function

Research reveals that gestational exposure to air pollution increases cord blood cystatin C levels, indicating potential kidney function issues in newborns.

2 Sep 2024

Tirzepatide outperforms insulin in controlling diabetes and promoting weight loss in clinical trials

Tirzepatide, a once-weekly dual agonist, outperforms long-acting insulin in reducing HbA1c, body weight, and improving cardiovascular markers in Type 2 diabetes patients.

2 Sep 2024

NCCS study uses exosomes to overcome resistance to epidermal growth factor receptor inhibitors

In a new study, clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS) have demonstrated the use of exosomes to successfully target squamous cell cancer tumours that are usually resistant to epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs). Their research is the first where exosomes have been applied to target TKI-resistant cancers in Singapore. The findings were published in the journal Developmental Cell last month.

2 Sep 2024

Fermented lingonberry juice shown to reduce inflammation and support gut health in IBD

Fermented lingonberry juice may help manage inflammatory bowel disease (IBD) by modulating both the oral and gut microbiomes, reducing inflammation, and promoting beneficial bacteria.

2 Sep 2024

Study finds wearable monitors effective in diagnosing atrial fibrillation

Wearable, long-term continuous heart monitors helped identify 52% more cases of atrial fibrillation compared to usual care, but that did not lead to a reduction in hospitalizations due to stroke, according to a study led by the Duke Clinical Research Institute.

1 Sep 2024

Study finds higher heart attack risk days after cold exposure

Hospital admissions for heart attacks increase after exposure to lower air temperature and cold spells, according to a study published today in JACC, the flagship journal of the American College of Cardiology, and presented at the European Society of Cardiology (ESC) Congress 2024.

1 Sep 2024

Edoxaban monotherapy superior to dual therapy in patients with high-risk AF and stable CAD

Edoxaban monotherapy reduced net adverse clinical events compared with edoxaban plus a single antiplatelet agent, when used as long-term antithrombotic therapy, in patients with high-risk atrial fibrillation (AF) and stable coronary artery disease (CAD), according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

OCEANIC-AF trial reveals inferiority of asundexian to apixaban for stroke prevention

Asundexian 50 mg daily was inferior to apixaban for stroke and systemic embolism prevention in high-risk patients with atrial fibrillation (AF), according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

New study confirms safety of SGLT2 inhibitors after acute myocardial infarction

The SGLT2 inhibitor empagliflozin confers kidney-protective benefits and can therefore be given safely and effectively to patients when they are hospitalized for acute myocardial infarction (MI), a Mount Sinai-led global team of researchers has shown.

1 Sep 2024

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Medical Condition News

Pooled analysis shows finerenone reduces all-cause mortality but not cardiovascular death

Study reveals key genetic markers for early onset bicuspid aortic valve complications

Breakthrough in blood stem cell development offers hope for leukemia and bone marrow failure

Study finds no added benefit of extensive ablation for persistent atrial fibrillation

Fasting before cardiac catheterization not necessary, study finds

Mineralocorticoid receptor antagonists benefit heart failure patients across ejection fractions

Cryoballoon ablation as effective as radiofrequency for atrial fibrillation in heart failure patients

Catheter ablation proven effective for atrial fibrillation in new study

Finerenone shows promise for heart failure with mildly reduced or preserved ejection fraction

Study identifies key predictors of severe mpox cases

Recent studies underscore the importance of diet for the prevention of cancer

Research finds particulate pollution during pregnancy may impact newborn kidney function

Tirzepatide outperforms insulin in controlling diabetes and promoting weight loss in clinical trials

NCCS study uses exosomes to overcome resistance to epidermal growth factor receptor inhibitors

Fermented lingonberry juice shown to reduce inflammation and support gut health in IBD

Study finds wearable monitors effective in diagnosing atrial fibrillation

Study finds higher heart attack risk days after cold exposure

Edoxaban monotherapy superior to dual therapy in patients with high-risk AF and stable CAD

OCEANIC-AF trial reveals inferiority of asundexian to apixaban for stroke prevention

New study confirms safety of SGLT2 inhibitors after acute myocardial infarction

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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