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U.S. launches national plan to tackle Parkinson's disease and related disorders

With support from the U.S. Department of Health and Human Services (HHS) Office of the Assistant Secretary for Health (OASH), the National Institutes of Health (NIH) is leading the implementation of the Dr. Emmanuel Bilirakis and Honorable Jennifer Wexton National Plan to End Parkinson's Act (P.L. 118-66), which was signed into law on July 2, 2024.

17 Jan 2025

Study evaluates effectiveness and safety of TMF for chronic hepatitis B

Chronic hepatitis B (CHB) remains a significant global health challenge, and effective antiviral therapies are essential for long-term management.

17 Jan 2025

New probes offer insight into cholesterol's role in Alzheimer's disease

The search for answers to Alzheimer's disease and other neurodegenerative disorders remains one of the most pressing goals in brain research. Maciej J. Stawikowski, Ph.D., an assistant professor of chemistry and biochemistry at Florida Atlantic University's Charles E. Schmidt College of Science, believes the key may lie in understanding how cholesterol and other lipids move through cells and affect their communication.

17 Jan 2025

Qigong shows promise in reducing chronic back pain in veterans

Chronic pain is widespread in the United States, particularly among military veterans, affecting between 40 to 70% of this population and serving as a leading cause of disability.

17 Jan 2025

High out-of-pocket costs reduce participation in cardiac rehabilitation

Despite the success cardiac rehabilitation has shown at reducing heart-related deaths and hospital readmissions, higher out-of-pocket costs may prevent patients from participating in the program, a Michigan Medicine study suggests.

17 Jan 2025

New clinical trial aims to extend survival for bile duct cancer patients

A new clinical trial, sponsored by UCL and UCLH, aims to extend survival for some patients with cancer in the biliary tract by treating them with therapies specifically tailored to the genetic profile of their tumor.

17 Jan 2025

New study links cervicovaginal microbiome to increased risk of Chlamydia infections

The cervicovaginal microbiome's role in Chlamydia infections underscores the need for molecular classification to enhance prevention and treatment strategies.

17 Jan 2025

Granzyme K+ CD8+ T-cells identified as key drivers of recurrent airway inflammation

Researchers identify a pathogenic subset of CD8+ memory T-cells that promote airway tissue inflammation and recurrent respiratory diseases.

17 Jan 2025

Inflammasome proteins found to prevent cancer by regulating stem cells

A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from their surfaces and blocking cancer gene activity, according to a preclinical study by Weill Cornell Medicine investigators.

17 Jan 2025

Intestinal bacterium found to reduce sugar intake in diabetic mice and humans

Excessive sugar consumption is linked to several non-communicable diseases, including obesity, cardiovascular disease, metabolic syndrome, and type 2 diabetes.

17 Jan 2025

Over 500 European patients diagnosed through groundbreaking genetic research

More than 500 European patients with unknown conditions have received a diagnosis through new genetic research.

17 Jan 2025

Early brain changes in Huntington’s disease detected two decades before symptoms

Subtle changes in the brain, detectable through advanced imaging, blood and spinal fluid analysis, happen approximately twenty years before a clinical motor diagnosis in people with Huntington's disease, finds a new study led by UCL researchers.

17 Jan 2025

Tofacitinib reduces SARS-CoV-2 infection risk in patients with PTPN2 deficiency

Researchers report the ability of tofacitinib to reduce infection risk with SARS-CoV-2 in individuals who are deficient in PTPN2.

17 Jan 2025

Triple-drug chemo fails to improve survival in advanced biliary tract cancer

The results of a clinical trial led by researchers at the University of Arizona Health Sciences and published in the Journal of Clinical Oncology showed that chemotherapy combining three different types of drugs did not improve overall survival for patients with advanced stage, inoperable biliary tract cancers.

17 Jan 2025

Unveiling the metabolic pathways of Fusobacterium nucleatum in OSCC

A recent study has made significant strides in uncovering how the oral microbiome, particularly the bacterium Fusobacterium nucleatum, plays a crucial role in the progression of oral squamous cell carcinoma (OSCC). By identifying key interactions between this common oral bacterium and host cells, the research has unveiled important metabolic pathways and mechanisms that may serve as potential therapeutic targets.

17 Jan 2025

New approach shows promise in fighting multiple cancers

The tissue adjacent to a tumor behaves differently than areas farther away: The tumor's cancerous cells influence their surroundings, blocking the body's immune defenses and creating a sort of haven in which the tumor can grow. Treatments that target some of these pro-tumor actions are effective in a number of cancers, but only for some patients; in others, these treatments have little effect.

17 Jan 2025

Air pollution amplifies dementia risk in cardiometabolic disease patients - healthy habits can help

CMD patients face a 2x higher risk of dementia and MCI, but healthier lifestyles can counter air pollution's impact and reduce these risks.

16 Jan 2025

COVID-19 dramatically raises the risk of developing ME/CFS

Study highlights a fourfold increase in ME/CFS risk among COVID-19 patients, with 89% of post-COVID ME/CFS cases overlapping with severe long COVID symptom clusters.

16 Jan 2025

Study finds lasting benefits of multifocal contact lenses in slowing myopia

Capping ten years of work to stem the tide of nearsightedness, David Berntsen, Golden-Golden Professor of Optometry and chair of Clinical Sciences at the University of Houston College of Optometry, is reporting that his team's method to slow myopia not only works – but lasts.

16 Jan 2025

Non-toxic bacterial therapy shows promise for targeting tumors

A University of Massachusetts Amherst-Ernest Pharmaceuticals team of scientists has made "exciting," patient-friendly advances in developing a non-toxic bacterial therapy, BacID, to deliver cancer-fighting drugs directly into tumors.

16 Jan 2025