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New NIH grants support research that combines DNA sequence information and electronic medical records

A dozen awards from the National Institutes of Health will support research that incorporates DNA sequence information into electronic medical records. The goal of research conducted by the Electronic Medical Records and Genomics (eMERGE) network is to better understand the genomic basis of disease and to tailor medical care to individual patients based on their genomic differences.

2 Sep 2015

Common antidepressant can help stroke patients improve movement and coordination

Working with mice, researchers at Johns Hopkins have added to evidence that a commonly prescribed antidepressant called fluoxetine helps stroke victims improve movement and coordination, and possibly why.

2 Sep 2015

First-line catheter ablation treatment superior to drug therapy for suppressing AF

First-line treatment with catheter ablation is superior to drug therapy for reducing atrial fibrillation, according to five year results from the MANTRA-PAF trial presented for the first time at ESC Congress today.

2 Sep 2015

New study provides biological explanation for how DMPA increases risk of HIV infection

In recent years, evidence has been building that injectable contraceptive depot medroxyprogesterone acetate (Depo-Provera or DMPA) is associated with an increased risk of HIV infection. Now a study published in the September 1st issue of mBio, an online open-access journal of the American Society for Microbiology, provides a biological explanation for the phenomenon.

2 Sep 2015

Mouse study shows active ingredient in marijuana may delay rejection of incompatible organs

Here's another discovery to bolster the case for medical marijuana: New research in mice suggests that THC, the active ingredient in marijuana, may delay the rejection of incompatible organs.

2 Sep 2015

Researchers reveal how the brain manages multitasking

What makes someone better at switching between different tasks? Looking for the mechanisms behind cognitive flexibility, researchers at the University of Pennsylvania and Germany's Central Institute of Mental Health in Mannheim and Charité University Medicine Berlin have used brain scans to shed new light on this question.

2 Sep 2015

A unique perspective on health and exercise

For over 30 years, Terrie Williams has been studying exercise physiology in wild animals: African lions and wild dogs, dolphins and whales, coyotes and mountain lions, as well as a few human athletes.

2 Sep 2015

Preterm birth associated with lower academic abilities in childhood, less wealth in adulthood

People who are born premature tend to accumulate less wealth as adults, and a new study suggests that this may be due to lower mathematics abilities. The findings, published in Psychological Science, a journal of the Association for Psychological Science, show that preterm birth is associated with lower academic abilities in childhood, and lower educational attainment and less wealth in adulthood.

2 Sep 2015

Report: 3 out of 4 U.S. adults have hearts older than their actual age

Your heart may be older than you are – and that's not good. According to a new CDC Vital Signs report, 3 out of 4 U.S. adults have a predicted heart age that is older than their actual age. This means they are at higher risk for heart attacks and stroke.

2 Sep 2015

U-M study suggests potential treatment options for children with aggressive, advanced cancer

For children with rare, aggressive and advanced cancer, precision medicine may help doctors determine their best treatment options, a new study finds.

2 Sep 2015

Researchers explore how different facets of forgiveness affect feelings of depression in aging adults

Forgiveness is a complex process, one often fraught with difficulty and angst. Now, researchers in the University of Missouri College of Human Environmental Sciences studied how different facets of forgiveness affected aging adults' feelings of depression.

2 Sep 2015

Finerenone drug improves albuminuria among patients with diabetes and kidney disease

Among patients with diabetes and kidney disease, most receiving an angiotensin-converting enzyme inhibitor or an angiotensin receptor blocker, the addition of the medication finerenone compared with placebo resulted in improvement in albuminuria (the presence of excessive protein [chiefly albumin] in the urine), according to a study in the September 1 issue of JAMA.

2 Sep 2015

SKA2 gene may play a role in development of PTSD

A gene linked in previous research, appears to predict more severe post-traumatic stress disorder (PTSD) symptoms as well as a thinner cortex in regions of the brain critical for regulating strong emotions and coping with stressful experiences. This study is believed to be the first to show that the spindle and kinetochore-associated complex subunit 2 (SKA2) gene may play a role in the development of PTSD.

2 Sep 2015

Familial hypercholesterolemia patients can benefit from alirocumab drug

Alirocumab lowers cholesterol in patients with heterozygous familial hypercholesterolemia to levels unreachable with statins alone, according to results from four ODYSSEY trials presented at ESC Congress today.

2 Sep 2015

Diagnosing traumatic brain injury through a blood test: an interview with Dr Korley

The severity of traumatic brain injury is currently crudely classified as mild, moderate or severe. However, often patients referred to as mild have debilitating symptoms that are not “mild”. Additionally, there are patients currently classified as moderate or severe who regain their pre-injury functional status whereas others don’t.

1 Sep 2015

Administering ticagrelor in the ambulance cuts ischaemic events 24 hours following PCI

Ticagrelor administered in the ambulance reduces ischaemic events 24 hours after primary percutaneous coronary intervention (PCI), according to findings from the ATLANTIC-H24 study presented for the first time today at ESC Congress.

1 Sep 2015

Men with relatively unaggressive prostate tumors unlikely to develop metastatic prostate cancer

Men with relatively unaggressive prostate tumors and whose disease is carefully monitored by urologists are unlikely to develop metastatic prostate cancer or die of their cancers, according to results of a study by researchers at the Brady Urological Institute at Johns Hopkins, who analyzed survival statistics up to 15 years.

1 Sep 2015

North Shore-LIJ researcher compares safety benefits two blood-thinning medications

A large, ambitious contrast of blood-thinning medications used during cardiac stent placement suggests that a very expensive drug offers no clear safety benefits over a much more affordable option, according to a prominent North Shore-LIJ researcher and cardiologist.

1 Sep 2015

New statistical model may help predict patients most likely to benefits from surgical treatment for mesothelioma

A new statistical model may help predict which patients are most likely to receive life-extending benefits from surgical treatment for malignant pleural mesothelioma (MPM), according to an article in the September 2015 issue of The Annals of Thoracic Surgery.

1 Sep 2015

Finerenone effective in heart failure patients with diabetes and/or chronic kidney disease

In heart failure patients with diabetes and/or chronic kidney disease, a new, non-steroidal mineralocorticoid receptor antagonist (MRA) called finerenone was no more effective than the currently approved MRA eplerenone in reducing the heart failure biomarker N-terminal pro-B-type natriuretic peptide [NT-proBNP].

1 Sep 2015

Medical Research News

New NIH grants support research that combines DNA sequence information and electronic medical records

Common antidepressant can help stroke patients improve movement and coordination

First-line catheter ablation treatment superior to drug therapy for suppressing AF

New study provides biological explanation for how DMPA increases risk of HIV infection

Mouse study shows active ingredient in marijuana may delay rejection of incompatible organs

Researchers reveal how the brain manages multitasking

A unique perspective on health and exercise

Preterm birth associated with lower academic abilities in childhood, less wealth in adulthood

Report: 3 out of 4 U.S. adults have hearts older than their actual age

U-M study suggests potential treatment options for children with aggressive, advanced cancer

Researchers explore how different facets of forgiveness affect feelings of depression in aging adults

Finerenone drug improves albuminuria among patients with diabetes and kidney disease

SKA2 gene may play a role in development of PTSD

Familial hypercholesterolemia patients can benefit from alirocumab drug

Diagnosing traumatic brain injury through a blood test: an interview with Dr Korley

Administering ticagrelor in the ambulance cuts ischaemic events 24 hours following PCI

Men with relatively unaggressive prostate tumors unlikely to develop metastatic prostate cancer

North Shore-LIJ researcher compares safety benefits two blood-thinning medications

New statistical model may help predict patients most likely to benefits from surgical treatment for mesothelioma

Finerenone effective in heart failure patients with diabetes and/or chronic kidney disease

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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