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CPMC study discovers six genes that affect sleep duration

The Coriell Personalized Medicine Collaborative, a research initiative exploring the utility of genetic information in the clinical setting, has published a study and identified six noteworthy genes that affect human sleep duration.

13 Jan 2016

Sedentary behavior associated with poor cardiovascular health, diabetes in people with severe obesity

Sedentary behavior is associated with poor cardiovascular health and diabetes in adults with severe obesity, independent of how much exercise they perform, a University of Pittsburgh Graduate School of Public Health-led study showed for the first time.

13 Jan 2016

New gene-filtering tool aims to predict disease-causing mutations

Despite their bad reputations, the vast majority of mutations are not harmful. Even in very rare genetic disorders, only one or two genetic variations — out of tens of thousands — is actually the cause of disease. Distinguishing between harmful and harmless mutations has long been a challenge.

13 Jan 2016

High doses of vitamin D may increase risk of falls

According to new research summarized by California Pacific Medical Center Research Institute senior scientist Steven Cummings, MD, and colleagues at the University of California, San Francisco and Harvard Medical School, contrary to common beliefs, relatively high doses of vitamin D may increase the risk of falls.

13 Jan 2016

New mechanism of differentiation may offer novel therapeutic approaches to blood malignancies, solid tumors

In humans the differentiation of stem cells into hundreds of specialized cell types is vital. Differentiation drives development from fertilized egg to a newborn, and it underlies the continuous replacement of the 5 billion cells that die every hour in an adult. On the downside, mutations in differentiation pathways of different cell types can be drivers of cancers.

13 Jan 2016

Minority and ethnic groups diagnosed with colorectal cancer at younger ages

Colorectal cancer is the third most common form of cancer and the second most common cause of cancer deaths in the United States. The chance of developing colorectal cancer increases with age. Now, a study by University of Missouri School of Medicine researchers shows that minority and ethnic groups are being diagnosed with colorectal cancer at younger ages and more advanced stages than non-Hispanic whites.

12 Jan 2016

Young children in deep poverty fare worse on health and development indicators

Young children in deep poverty, whose family income is below 50 percent of the federal poverty line, fare even worse on health and development indicators than children in poverty, according to a study released by the National Center for Children in Poverty at Columbia University's Mailman School of Public Health.

12 Jan 2016

Pre-existing nutritional deficits, immune dysfunction may increase hepatitis E risk during pregnancy

Researchers from the Johns Hopkins Bloomberg School of Public Health have found a link between pre-existing nutritional deficits and immune dysfunction and the risk of hepatitis E infection during pregnancy.

12 Jan 2016

Researchers discover molecular target for DNA repair defects behind Fanconi anemia

Researchers have identified a molecular target and experimental treatment strategy for DNA repair defects behind Fanconi anemia – a complex genetic disorder responsible for birth anomalies, organ damage, anemia and cancer.

12 Jan 2016

Study examines impact of sit-stand workstations in reducing chronic low back pain in office workers

Low back pain is one of the most common causes of job-related disabilities, influencing employee productivity and ultimately significantly impacting the economic well-being of a business. A pilot study by researchers at the Stanford University School of Medicine examined whether access to the sit-stand workstations could help reduce or relieve chronic low back pain in office workers.

12 Jan 2016

IMB scientists identify two proteins vital for demethylation of DNA

Scientists at the Institute of Molecular Biology in Mainz have identified a missing piece of the puzzle in understanding how epigenetic marks are removed from DNA. The research on DNA demethylation sheds new light on a fundamental process that is important in development and diseases such as cancer.

12 Jan 2016

Scientists identify unusual regulator of body weight, metabolic syndrome

Scientists at the Gladstone Institutes have discovered an unusual regulator of body weight and the metabolic syndrome: a molecular mechanism more commonly associated with brain cells. Lowering levels of P75 neurotrophin receptor (NTR)--a receptor involved in neuron growth and survival--protected mice fed a high-fat diet from developing obesity, diabetes, and fatty liver disease.

12 Jan 2016

Regular practice of Transcendental Meditation benefits active-duty service members

Regular practice of Transcendental Meditation enables some active duty service members battling post-traumatic stress disorder to reduce or even eliminate their psychotropic medication and get better control of their often-debilitating symptoms, researchers report in the journal Military Medicine.

12 Jan 2016

U of I experiment provides insight on variables that may affect opinions about organic foods

The organic food industry has grown from fresh produce and grains to snack foods and condiments--from farmers markets to supercenters. Has this new variety in organic products, and the availability of them, affected consumers' perceptions? A University of Illinois researcher and her team designed an experiment to provide insight on some of the variables that may influence opinions about organic foods.

12 Jan 2016

Three new genetic associations identified for primary open angle glaucoma

Researchers from Massachusetts Eye and Ear/Harvard Medical School and Case Western Reserve University School of Medicine have led an international effort to identify three genetic associations that influence susceptibility to primary open angle glaucoma -- the most common form of adult onset glaucoma and the leading cause of irreversible blindness in the world.

12 Jan 2016

Food preservative delivers one-two punch to cancer, antibiotic-resistant bacteria

Nisin, a naturally occurring food preservative that grows on dairy products, delivers a one-two punch to two of medicine's most lethal maladies: cancer and deadly, antibiotic-resistant bacteria.

12 Jan 2016

Laser-induced breakdown spectroscopy emerges as fast, cost-efficient method for biomass analysis

Laser-induced breakdown spectroscopy (LIBS) is emerging as a fast, cost-efficient method for identifying the total amount and specific compounds that comprise the inorganic component of biomass. Accurate and reliable analysis of these minerals, such as aluminum, calcium, iron, and silicon is essential, as this "ash" can cause problems when converting biomass to hydrocarbon biofuels, as described in a study published in Industrial Biotechnology, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

12 Jan 2016

NIH-funded analysis identifies three genes that contribute to most common form of glaucoma

An analysis funded by the National Eye Institute (NEI), part of the National Institutes of Health, has identified three genes that contribute to the most common type of glaucoma. The study increases the total number of such genes to 15.

12 Jan 2016

Malaysian scientists join forces with Harvard experts to help revolutionize lung disease treatment

Malaysian scientists are joining forces with Harvard University experts to help revolutionize the treatment of lung diseases -- the delivery of nanomedicine deep into places otherwise impossible to reach.

12 Jan 2016

New studies provide insights into impact of vision loss among survivors of childhood cancers

Little is known about the long-term health of survivors of childhood cancers that affect vision, but two new studies provide valuable insights that could impact patient care and follow-up. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer Society.

12 Jan 2016

Medical Research News

CPMC study discovers six genes that affect sleep duration

Sedentary behavior associated with poor cardiovascular health, diabetes in people with severe obesity

New gene-filtering tool aims to predict disease-causing mutations

High doses of vitamin D may increase risk of falls

New mechanism of differentiation may offer novel therapeutic approaches to blood malignancies, solid tumors

Minority and ethnic groups diagnosed with colorectal cancer at younger ages

Young children in deep poverty fare worse on health and development indicators

Pre-existing nutritional deficits, immune dysfunction may increase hepatitis E risk during pregnancy

Researchers discover molecular target for DNA repair defects behind Fanconi anemia

Study examines impact of sit-stand workstations in reducing chronic low back pain in office workers

IMB scientists identify two proteins vital for demethylation of DNA

Scientists identify unusual regulator of body weight, metabolic syndrome

Regular practice of Transcendental Meditation benefits active-duty service members

U of I experiment provides insight on variables that may affect opinions about organic foods

Three new genetic associations identified for primary open angle glaucoma

Food preservative delivers one-two punch to cancer, antibiotic-resistant bacteria

Laser-induced breakdown spectroscopy emerges as fast, cost-efficient method for biomass analysis

NIH-funded analysis identifies three genes that contribute to most common form of glaucoma

Malaysian scientists join forces with Harvard experts to help revolutionize lung disease treatment

New studies provide insights into impact of vision loss among survivors of childhood cancers

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

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