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$Gene transfer therapy not beneficial for heart failure patients with reduced ejection fraction$

Gene transfer therapy not beneficial for heart failure patients with reduced ejection fraction

Gene transfer therapy aimed at correcting an enzyme abnormality involved in myocardial contraction and relaxation did not improve outcomes in heart failure patients with reduced ejection fraction, results of the CUPID 2 study show.

1 Sep 2015

Breakthrough discovery provides better understanding of Alzheimer’s disease

Alzheimer's disease is associated with the appearance of characteristic neurotoxic protein aggregates in various regions in the brain.

1 Sep 2015

InterSystems plans to launch next-generation laboratory business management system in 2016

InterSystems, a global leader in software for connected care and developer of the InterSystems TrakCare unified healthcare information system, today announced that it will release its next-generation laboratory business management system (LBMS) in early 2016.

1 Sep 2015

Gene therapy restores visual function in mouse model of LCA1

Mice lacking the protein retGC1, which is deficient in humans suffering Leber congenital amaurosis-1 (LCA1), a disorder that causes severe visual impairment beginning in infancy, received gene therapy to replace retGC1 and showed fully restored visual function that persisted for at least 6 months.

1 Sep 2015

Benznidazole has significant antiparasitic activity, but does not reduce progression of Chagas cardiomyopathy

A 40 to 80 day treatment with the antiparasitic medication benznidazole significantly reduced parasite activity in the blood, but not progression, of serious heart problems over a 5-year period among patients with established Chagas disease (CD) cardiomyopathy, results of the BENEFIT trial show.

1 Sep 2015

UC Davis Health System research shows that increasing minimum wage may reduce smoking rates

In addition to restricting when and where tobacco is used at work, UC Davis Health System research shows that employers can do something else to reduce smoking: raise wages.

1 Sep 2015

ASV therapy used to treat central sleep apnoea in heart failure patients increases mortality

Adaptive servo-ventilation (ASV) therapy increases mortality and should not be used to treat central sleep apnoea in heart failure patients with reduced ejection fraction, the SERVE-HF trial shows.

1 Sep 2015

Scientists elucidate chemical process behind eosinophilic esophagitis

Scientists from the D'Or Institute of Research and Education, the Federal University of Rio de Janeiro and the Yale University School of Medicine have elucidated the chemical process behind a mysterious gastrointestinal disease that is becoming more frequent every day: the eosinophilic esophagitis (EoE), also known as the "asthma of the esophagus".

1 Sep 2015

UCSF-led team develops new technique to create tiny models of human tissues

A UCSF-led team has developed a technique to build tiny models of human tissues, called organoids, more precisely than ever before using a process that turns human cells into a biological equivalent of LEGO bricks. These mini-tissues in a dish can be used to study how particular structural features of tissue affect normal growth or go awry in cancer. They could be used for therapeutic drug screening and to help teach researchers how to grow whole human organs.

1 Sep 2015

Newly discovered prion causes Multiple System Atrophy

Multiple System Atrophy (MSA), a neurodegenerative disorder with similarities to Parkinson's disease, is caused by a newly discovered type of prion, akin to the misfolded proteins involved in incurable progressive brain diseases such Creutzfeldt-Jakob Disease (CJD), according to two new research papers led by scientists at UC San Francisco.

1 Sep 2015

Study: Inner-city neighbourhoods may affect risk of dying from cardiovascular disease

The inner-city neighbourhood in which someone lives may affect his or her risk of developing or dying from cardiovascular disease, a new research paper suggests.

1 Sep 2015

Study sheds light on ways to improve embryonic wound healing in humans

It's like something out of a science-fiction movie - time-lapse photography showing how wounds in embryos of fruit flies heal themselves. The images are not only real; they shed light on ways to improve wound recovery in humans.

1 Sep 2015

Carbonated beverage consumption associated with out-of-hospital cardiac arrests of cardiac origin

Carbonated beverages are associated with out-of-hospital cardiac arrests of cardiac origin, according to results from the All-Japan Utstein Registry presented for the first time today at ESC Congress.

1 Sep 2015

Northwestern University receives $11.7 million NCI grant to use nanotechnology for cancer treatments

Northwestern University, a leader in cancer nanotechnology research, has received a five-year, $11.7 million grant from the National Cancer Institute to use nanotechnology to develop next-generation cancer treatments.

1 Sep 2015

Watching TV linked to subsequent obesity for young adults

The more hours young adults spend watching television each day, the greater the likelihood that they'll have a higher body mass index and bigger waist circumference, a 15-year analysis by the University of Pittsburgh Graduate School of Public Health revealed.

1 Sep 2015

Young diabetic women have six-fold heart attack risk

Women aged 45 years and under with diabetes have a six-fold risk of heart attack, according to research presented at ESC Congress today.1 The study in more than 7 000 women also found that young women who had a heart attack (myocardial infarction, MI) were more likely to be smokers than older women with MI.

1 Sep 2015

MACC1 gene can help predict better treatment options for patients with Klatskin carcinoma

Bile duct cancer is rare and is usually detected too late. Often only extensive liver surgery can help or, in rare cases, liver transplantation. But which patients will benefit from surgery and which will not, because their risk of cancer recurrence is too high? With the oncogene MACC1 as a biomarker, physicians for the first time have a tool to decide which treatment option is best for patients with Klatskin carcinoma, one type of bile duct cancer.

1 Sep 2015

New $6.25 million NIH grant to help investigators launch research center to slow and stop HIV

A new five-year, $6.25 million grant from the National Institutes of Health will help investigators from Northwestern University, the University of Chicago and others across the city of Chicago work together to slow and stop HIV.

1 Sep 2015

Mayo Clinic study identifies benchmarks for postsurgical outcomes in patients with colorectal cancer

About 20 percent of colorectal cancer patients have cancers that have spread (metastasized) beyond the colon at the time of their diagnosis. The liver is the most common site for these metastases. The approach to treating primary tumors within the colon and metastatic tumors in the liver continues to evolve; however, it typically involves chemotherapy plus surgical removal (resection) of both types of tumors. However, experts continue to debate whether surgical resection of primary tumors and metastatic tumors should be performed at the same time (synchronously) or in separate operations (sequentially).

1 Sep 2015

Repetitive transcranial magnetic stimulation can alleviate FOG, improve motor skills in PD patients

About 50% of patients with Parkinson's disease (PD) experience freezing of gait (FOG), an inability to move forward while walking. This can affect not only mobility but also balance. In a new study published in Restorative Neurology and Neuroscience, researchers report that repetitive transcranial magnetic stimulation (rTMS) can reduce FOG and improve other motor skills in PD patients.

1 Sep 2015

Medical Research News

Gene transfer therapy not beneficial for heart failure patients with reduced ejection fraction

Breakthrough discovery provides better understanding of Alzheimer’s disease

InterSystems plans to launch next-generation laboratory business management system in 2016

Gene therapy restores visual function in mouse model of LCA1

Benznidazole has significant antiparasitic activity, but does not reduce progression of Chagas cardiomyopathy

UC Davis Health System research shows that increasing minimum wage may reduce smoking rates

ASV therapy used to treat central sleep apnoea in heart failure patients increases mortality

Scientists elucidate chemical process behind eosinophilic esophagitis

UCSF-led team develops new technique to create tiny models of human tissues

Newly discovered prion causes Multiple System Atrophy

Study: Inner-city neighbourhoods may affect risk of dying from cardiovascular disease

Study sheds light on ways to improve embryonic wound healing in humans

Carbonated beverage consumption associated with out-of-hospital cardiac arrests of cardiac origin

Northwestern University receives $11.7 million NCI grant to use nanotechnology for cancer treatments

Watching TV linked to subsequent obesity for young adults

Young diabetic women have six-fold heart attack risk

MACC1 gene can help predict better treatment options for patients with Klatskin carcinoma

New $6.25 million NIH grant to help investigators launch research center to slow and stop HIV

Mayo Clinic study identifies benchmarks for postsurgical outcomes in patients with colorectal cancer

Repetitive transcranial magnetic stimulation can alleviate FOG, improve motor skills in PD patients

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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