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Older patients more likely to be readmitted to hospital after ambulatory surgery

Patients 65 and older who have ambulatory surgery are much more likely to be readmitted to the hospital within 30 days than younger patients, regardless of their health before surgery, reports a new, large national Northwestern Medicine study. The likely cause, based on previous research, is difficulty understanding medication dosing and discharge instructions, as well as cognitive impairment among older patients.

11 Aug 2015

Researchers apply new approach to make improved nasal spray flu vaccine

Johns Hopkins Bloomberg School of Public Health researchers say they have developed a method that could make a nasal spray flu vaccine effective for those under two and over 49 - two groups for which the vaccine is not approved.

11 Aug 2015

CSN6 protein linked to poor survival among patients with colorectal cancer

A protein called CSN6 has been found to be correlated with poor survival among patients with colorectal cancer, according to a study at The University of Texas MD Anderson Cancer Center.

11 Aug 2015

Case Western Reserve awarded federal grant for nutritious food access study

The National Institutes of Health (NIH) has awarded $2.3 million to Case Western Reserve to lead a collaborative study of how changes in food options affect residents' nutritional choices and health over time.

11 Aug 2015

Major gaps found in existing evidence for best practices for cleaning hospital room surfaces to prevent HAIs

Tray tables, bed rails, light switches, and toilets: All are common vectors for swapping germs between patients and health care workers. While a new systematic overview in this week's Annals of Internal Medicine points to several promising cleaning tactics of these "high-touch surfaces," there's a lack of evidence as to which is the most effective at reducing healthcare-associated infections (HAIs).

11 Aug 2015

Researchers report role of two gene-regulating molecules in Parkinson's disease

As Parkinson's disease progresses in patients, a puzzling dichotomy plays out in their brains. One set of neurons degenerates, while a similar population nearby is spared the same degree of damage. Why the difference? An answer to this question could clear the way for preventions and treatments for this disease, which impairs movement.

11 Aug 2015

Study reveals that miR-7 suppresses gastric cancer by inhibiting key signaling pathway

A study in The Journal of Cell Biology reveals that the microRNA miR-7 suppresses gastric (stomach) cancer by inhibiting a key signaling pathway, and that this protective mechanism is compromised by the cancer-causing bacterium H. pylori. Finding drugs capable of inducing miR-7 could therefore prove to be an effective treatment against the progression of gastric cancer.

11 Aug 2015

Researchers identify first gene that causes common form of mitral valve prolapse

An international research collaboration led by Massachusetts General Hospital investigators has identified the first gene in which mutations cause the common form of mitral valve prolapse (MVP), a heart valve disorder that affects almost 2.5 percent of the population.

11 Aug 2015

LA BioMed's Nagendra Mishra to be honored with 2015 ICAAC Young Investigator Award

Nagendra Mishra, PhD, a Los Angeles Biomedical Research Institute researcher will be honored by the American Society of Microbiology with a 2015 Interscience Conference of Antimicrobial Agents and Chemotherapy Young Investigator Award during the conference Sept. 17-21 in San Diego.

11 Aug 2015

Novel treatment target found for RV failure in PAH

Researchers have identified a molecular pathway by which downregulation of microRNA-126 contributes to right ventricular failure in patients with pulmonary arterial hypertension.

10 Aug 2015

Low GLSRV heralds adverse outcomes in PAH patients

Impaired global longitudinal strain of the right ventricle predicts adverse outcomes in patients with pulmonary arterial hypertension, say investigators.

10 Aug 2015

Meta-analysis confirms oral contraceptives reduce endometrial cancer risk

Oral contraceptive use protects against endometrial cancer, with effects persisting for decades after cessation of use, shows a meta-analysis of individual patient data published in The Lancet Oncology.

10 Aug 2015

CRI to honor three scientists for contributions to immunology and cancer immunotherapy research

The Cancer Research Institute, a nonprofit organization dedicated to fueling the discovery and development of immunotherapies for all forms of cancer, will bestow its highest honors on three scientists who have made fundamental contributions to the fields of immunology and cancer immunotherapy.

10 Aug 2015

CRI announces winners of 2015 Oliver R. Grace Award for Distinguished Service in Advancing Cancer Research

The Cancer Research Institute, a nonprofit organization dedicated to fueling the discovery and development of immunotherapies for all forms of cancer, announced today the winners of the 2015 Oliver R. Grace Award for Distinguished Service in Advancing Cancer Research.

10 Aug 2015

Simple web-based programme to encourage handwashing reduces risk of respiratory tract infections

A web-based programme to encourage more frequent handwashing reduces the risk of catching and passing on respiratory tract infections to other household members, a randomised trial of more than 16,000 UK households published in The Lancet has found.

10 Aug 2015

High-risk patients not receiving recommended treatment for blood clots

Venous thromboembolism (VTE), encompassing deep-vein thrombosis (DVT), or blood clots in leg veins, and pulmonary embolism (PE), or clots that travel to the lungs, is the most common cause of preventable death in hospital settings. While these clots can be prevented by an approach called VTE prophylaxis, and this reduces mortality by as much as 80%, VTE prophylaxis is not universally prescribed for high-risk patients.

10 Aug 2015

New analyses examine role of religion, spirituality in cancer patients' mental, social and physical well-being

Research reveals that most individuals with cancer have religious and spiritual beliefs, or derive comfort from religious and spiritual experiences. But what impact does this have on patients' health? Recent analyses of all published studies on the topic--which included more than 44,000 patients--shed new light on the associations of religion and spirituality with cancer patients' mental, social, and physical well-being.

10 Aug 2015

Study: Out-of-home activities increase level of physical activity among older people

It is beneficial to stimulate older people to leave home to increase their level of physical activity, suggests the study of postdoctoral researcher Erja Portegijs. The study, conducted at the Gerontology Research Center of the University of Jyväskylä, showed that older people were more physically active on the days when they left home and went further away.

10 Aug 2015

Sheffield researchers win national awards for pioneering work on coeliac disease, IBS

Researchers at Sheffield Teaching Hospitals have received awards for their work investigating coeliac disease and irritable bowel syndrome, two common gastrointestinal conditions.

10 Aug 2015

Vascular side effects prevent first-line ponatinib use in chronic phase CML

Ponatinib is highly active when given to patients within 6 months of developing chronic phase chronic myeloid leukaemia, phase II results show, but its toxicity profile is unacceptable for first-line treatment.

7 Aug 2015

Medical Research News

Older patients more likely to be readmitted to hospital after ambulatory surgery

Researchers apply new approach to make improved nasal spray flu vaccine

CSN6 protein linked to poor survival among patients with colorectal cancer

Case Western Reserve awarded federal grant for nutritious food access study

Major gaps found in existing evidence for best practices for cleaning hospital room surfaces to prevent HAIs

Researchers report role of two gene-regulating molecules in Parkinson's disease

Study reveals that miR-7 suppresses gastric cancer by inhibiting key signaling pathway

Researchers identify first gene that causes common form of mitral valve prolapse

LA BioMed's Nagendra Mishra to be honored with 2015 ICAAC Young Investigator Award

Novel treatment target found for RV failure in PAH

Low GLSRV heralds adverse outcomes in PAH patients

Meta-analysis confirms oral contraceptives reduce endometrial cancer risk

CRI to honor three scientists for contributions to immunology and cancer immunotherapy research

CRI announces winners of 2015 Oliver R. Grace Award for Distinguished Service in Advancing Cancer Research

Simple web-based programme to encourage handwashing reduces risk of respiratory tract infections

High-risk patients not receiving recommended treatment for blood clots

New analyses examine role of religion, spirituality in cancer patients' mental, social and physical well-being

Study: Out-of-home activities increase level of physical activity among older people

Sheffield researchers win national awards for pioneering work on coeliac disease, IBS

Vascular side effects prevent first-line ponatinib use in chronic phase CML

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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