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MD Anderson scientists reveal role of metabolic enzyme fumarase in DNA repair

DNA double-strand breaks (DSBs) are the worst possible form of genetic malfunction that can cause cancer and resistance to therapy. New information published this week reveals more about why this occurs and how these breaks can be repaired.

4 Aug 2015

Weight cycling not associated with overall risk of cancer

The first comprehensive study of its kind finds weight cycling, repeated cycles of intentional weight loss followed by regain, was not associated with overall risk of cancer in men or women. The study by American Cancer Society investigators is the largest to date to investigate weight cycling with cancer risk.

4 Aug 2015

New Tel Aviv University study sheds light on precise trigger of deadly melanoma

Skin cancer is the most common of all cancers, and melanoma, which accounts for 2% of skin cancer cases, is responsible for nearly all skin cancer deaths. Melanoma rates in the US have been rising rapidly over the last 30 years, and although scientists have managed to identify key risk factors, melanoma's modus operandi has eluded the world of medical research.

4 Aug 2015

Pitt investigators to lead $5 million initiative to monitor resistance to HIV prevention drugs in sub-Saharan Africa

Infectious diseases researchers from the University of Pittsburgh School of Medicine are leading a five-year, $5 million initiative to monitor drug resistance during the rollout of HIV prevention drugs in sub-Saharan Africa.

4 Aug 2015

Engineered protein shown effective in patients with severe von Willebrand disease

The first protein engineered to help control bleeding episodes in patients with severe von Willebrand disease (vW disease) has been shown to be safe and effective, according to results of a Phase III trial.

4 Aug 2015

Combining chemotherapy and birinapant effective against high-grade serous ovarian cancer

High-grade serous ovarian cancer often responds well to the chemotherapy drug carboplatin, but why it so frequently comes back after treatment has been a medical mystery.

4 Aug 2015

RNA-binding protein ROQUIN regulates response to DNA damage

Messenger (mRNA) molecules are a key component of protein biosynthesis. They are first transcribed as a "working copy" of the DNA and then translated into protein molecules.

3 Aug 2015

Anti-dementia drugs could result in harmful weight loss, say researchers

Medications commonly used to treat dementia could result in harmful weight loss, according to UC San Francisco researchers, and clinicians need to account for this risk when prescribing these drugs to older adults, they said.

3 Aug 2015

New MS therapies associated with risks and side effects, require active management strategy

Advances in the treatment of Multiple Sclerosis have been good news for patients, but side effects and risks mean that an active management strategy and constant monitoring are essential.

3 Aug 2015

BUSM researchers find new way to detect and treat basal-like breast cancer

A new way to detect - and perhaps treat - one of the deadliest types of breast cancer has been found. Led by researchers at Boston University School of Medicine (BUSM), the study appears online in Breast Cancer Research.

3 Aug 2015

Researchers quantify growth and composition of breast tumours in living animal

The ability to visualize and characterize the composition of a tumour in detail during its development can provide valuable insights in order to target appropriate therapeutics.

3 Aug 2015

Researchers uncover strong evidence for genetic causes of cerebral palsy

Cerebral palsy (CP) is the most common cause of physical disability in children. It has historically been considered to be caused by factors such as birth asphyxia, stroke and infections in the developing brain of babies.

3 Aug 2015

High levels of specific proteins in urine can accurately detect early-stage pancreatic cancer

A combination of three proteins found at high levels in urine can accurately detect early-stage pancreatic cancer, UK researchers have found.

3 Aug 2015

UCLA skills program improves social functioning in young adults with autism

Researchers at the Semel Institute for Neuroscience and Human Behavior at UCLA have found that a social skills program for high-functioning young adults with autism spectrum disorder significantly improved the participants' ability to engage with their peers.

3 Aug 2015

Animal study shows children exposed to famine grow smaller, become susceptible to metabolic diseases

Starvation early in life can alter an organism for generations to come, according to a new study in roundworms. The effects are what Duke University biologist Ryan Baugh terms a "bet-hedging strategy."

3 Aug 2015

Environmental factors promote genetic mutations, have underappreciated effect on disease, evolution

Washington State University researchers say environmental factors are having an underappreciated effect on the course of disease and evolution by prompting genetic mutations through epigenetics, a process by which genes are turned on and off independent of an organism's DNA sequence.

3 Aug 2015

Medical Research News

MD Anderson scientists reveal role of metabolic enzyme fumarase in DNA repair

Weight cycling not associated with overall risk of cancer

New Tel Aviv University study sheds light on precise trigger of deadly melanoma

Pitt investigators to lead $5 million initiative to monitor resistance to HIV prevention drugs in sub-Saharan Africa

Engineered protein shown effective in patients with severe von Willebrand disease

Combining chemotherapy and birinapant effective against high-grade serous ovarian cancer

RNA-binding protein ROQUIN regulates response to DNA damage

Anti-dementia drugs could result in harmful weight loss, say researchers

New MS therapies associated with risks and side effects, require active management strategy

BUSM researchers find new way to detect and treat basal-like breast cancer

Researchers quantify growth and composition of breast tumours in living animal

Researchers uncover strong evidence for genetic causes of cerebral palsy

High levels of specific proteins in urine can accurately detect early-stage pancreatic cancer

UCLA skills program improves social functioning in young adults with autism

Animal study shows children exposed to famine grow smaller, become susceptible to metabolic diseases

Environmental factors promote genetic mutations, have underappreciated effect on disease, evolution

Common gout medications may offer protection from alcohol-induced liver disease, inflammation

Moderate and severe selective eating habits linked to depression, anxiety, shows study

New study on photoaging could minimize risk of skin cancer

Consuming alcohol at conception increases diabetes risk in offspring

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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