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Takeda completes post-marketing commitment and data submission for pioglitazone containing medicines

Takeda Pharmaceutical Company Limited today announced the completion of the study to fulfill the post-marketing commitment and submissions of data to regulatory authorities from the Pan European Multi-Database Bladder Cancer Risk Characterization Study, a large (n= 112,674), multi-database retrospective matched cohort study, conducted in four European countries, for pioglitazone containing medicines, including ACTOS with up to 10 years of follow-up.

31 Jul 2015

Researchers develop evidence-based model that can predict amount of nicotine released from e-cigarette

Virginia Commonwealth University Massey Cancer Center researchers at the VCU Center for the Study of Tobacco Products (CSTP) have developed the first ever, evidence-based model that can predict with up to 90 percent accuracy the amount of nicotine emitted by an electronic cigarette (e-cigarette).

31 Jul 2015

Female patients with depression have abnormally high expression levels of glutamate receptor genes

Numerous genes that regulate the activity of a neurotransmitter in the brain have been found to be abundant in brain tissue of depressed females. This could be an underlying cause of the higher incidence of suicide among women, according to research at the University of Illinois at Chicago.

31 Jul 2015

Researchers uncover master regulators that govern the fate of TFH cells

Follicular helper Tcells (TFH cells), a rare type of immune cell that is essential for inducing a strong and lasting antibody response to viruses and other microbes, have garnered intense interest in recent years but the molecular signals that drive their differentiation had remained unclear.

31 Jul 2015

New Penn study questions relevance of fish oil-derived SPMs and their anti-inflammatory effects in humans

The importance of a diet rich in fish oils - now a billion dollar food-supplement industry -- has been debated for over half a century. A few large clinical trials have supported the idea that fish oils confer therapeutic benefits to patients with cardiovascular disease. Researchers think that hearts and blood vessels may benefit in part from their anti-inflammatory properties.

31 Jul 2015

Patients with HPV traces post-treatment more likely to have oropharyngeal cancer recurrence

Oropharyngeal cancer patients who were found to have detectable traces of human papillomavirus type 16 (HPV16) in their saliva following cancer treatment are at an increased risk for recurrence, a study led by researchers at the Johns Hopkins Bloomberg School of Public Health has found.

31 Jul 2015

IU scientists find evidence that invisible war between microorganisms may affect human health

Health experts have warned for years that the overuse of antibiotics is creating "superbugs" able to resist drugs treating infection.

31 Jul 2015

IUPUI researchers receive NIH grant to study effect of depression treatment on cardiovascular disease

Indiana University-Purdue University Indianapolis researchers led by Jesse Stewart of the School of Science, have received a $2.6 million grant from the National Institutes of Health to conduct the first randomized controlled trial to determine whether depression treatment can help prevent the development of cardiovascular disease.

31 Jul 2015

Psychotropic medication use widespread among older adults, new study finds

Older Americans receive prescriptions for mental health medications at more than twice the rate that younger adults do, a new study finds.

31 Jul 2015

Pharmacist-included medical care teams help patients better control blood pressure

If you have hypertension, it pays to include a pharmacist in a medical care team. That's the upshot from research by the University of Iowa that found patients with uncontrolled hypertension had better blood pressure control when being cared for by pharmacists working in care teams (with a physician, for example) than patients who relied mostly on a doctor for medication guidance.

31 Jul 2015

DFG Senate Commission approves recommendations for developing clinical research at German universities

At the annual meeting of the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) on 30 June 2015, the Senate of the largest research funding organisation approved recommendations for "Developing Clinical Research at German Universities Between 2015 and 2025" (available in German).

30 Jul 2015

More work needed to support consumers after enrolling in insurance plan under Affordable Care Act

Enrolling in an insurance plan under the Affordable Care Act is only the first step for consumers to be actively engaged in their health care, according to a new analysis from RAND Corporation researchers.

30 Jul 2015

Novel 3D human skin tissue model could help detect presence of known skin sensitizers in medical device extracts

New research shows that exposing a 3D human skin tissue model to extracts of medical device materials can detect the presence of sensitizers known to cause an allergic response on contact in some individuals. Conventional skin sensitization testing of medical devices relies on animal testing, whereas human skin models could replace animal methods, according to an article in the new journal Applied In Vitro Toxicology, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers.

30 Jul 2015

Plants send out stress signals normally associated with animals

University of Adelaide research has shown for the first time that, despite not having a nervous system, plants use signals normally associated with animals when they encounter stress.

30 Jul 2015

Balancing cellular aging and cancer risk through biotechnology

In a way, trying to repair age-related heart damage and trying to fight cancer are opposite problems. Your heart cells' ability to regenerate themselves and proliferate into new, young cells degrades as you get older.

30 Jul 2015

Study reveals lingering effects of Superstorm Sandy among New Jersey residents

Superstorm Sandy continues to affect the lives of tens of thousands of New Jersey residents, in the form of unfinished repairs, disputed claims, and recurrent mold. These after-effects still linger for Sandy-impacted residents, and are associated with increased odds of residents experiencing mental health distress, post-traumatic stress disorder (PTSD), and depression.

30 Jul 2015

Researchers at Barrow Neurological Institute uncover brain surgery that changed history

Researchers at Barrow Neurological Institute have spent years of medical sleuthing across three continents to uncover a brain surgery that changed history.

30 Jul 2015

Research: Algae’s natural sunscreen molecules absorb UVA and UVB radiation with high efficiency

For consumers searching for just the right sunblock this summer, the options can be overwhelming. But scientists are now turning to the natural sunscreen of algae -- which is also found in fish slime -- to make a novel kind of shield against the sun's rays that could protect not only people, but also textiles and outdoor materials.

30 Jul 2015

Study on marine snails could help better understand underlying mechanisms of age-related memory loss

A new research study on marine snails uncovered the first cells in the nervous system to fail during aging. The University of Miami Rosenstiel School of Marine and Atmospheric Science researchers' findings are important to better understanding the underlying mechanisms of age-related memory loss in humans.

30 Jul 2015

New research shows promising progress in use of anti-inflammatory cytokine for T1D treatment

New research from Uppsala University shows promising progress in the use of anti-inflammatory cytokine for treatment of type 1 diabetes. The study, published in the open access journal Scientific Reports (Nature Publishing Group), reveals that administration of interleukin-35 (a protein made by immune cells) to mice with type 1 diabetes, reverses or cures the disease by maintaining a normal blood glucose level and the immune tolerance.

30 Jul 2015

Medical Research News

Takeda completes post-marketing commitment and data submission for pioglitazone containing medicines

Researchers develop evidence-based model that can predict amount of nicotine released from e-cigarette

Female patients with depression have abnormally high expression levels of glutamate receptor genes

Researchers uncover master regulators that govern the fate of TFH cells

New Penn study questions relevance of fish oil-derived SPMs and their anti-inflammatory effects in humans

Patients with HPV traces post-treatment more likely to have oropharyngeal cancer recurrence

IU scientists find evidence that invisible war between microorganisms may affect human health

IUPUI researchers receive NIH grant to study effect of depression treatment on cardiovascular disease

Psychotropic medication use widespread among older adults, new study finds

Pharmacist-included medical care teams help patients better control blood pressure

DFG Senate Commission approves recommendations for developing clinical research at German universities

More work needed to support consumers after enrolling in insurance plan under Affordable Care Act

Novel 3D human skin tissue model could help detect presence of known skin sensitizers in medical device extracts

Plants send out stress signals normally associated with animals

Balancing cellular aging and cancer risk through biotechnology

Study reveals lingering effects of Superstorm Sandy among New Jersey residents

Researchers at Barrow Neurological Institute uncover brain surgery that changed history

Research: Algae’s natural sunscreen molecules absorb UVA and UVB radiation with high efficiency

Study on marine snails could help better understand underlying mechanisms of age-related memory loss

New research shows promising progress in use of anti-inflammatory cytokine for T1D treatment

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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