Medical Research News

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Commonly prescribed drug also lowers blood pressure when combined with diuretic

With the growth of electronic medical records, research utilizing data from a large number of patients, known as big data studies, can provide important information which may be unattainable via clinical trials which tend to be costly, time-consuming and involve fewer patients.

30 Jul 2015

Bioenergetic analysis of pancreatic beta-cells shows impaired metabolic signature in type 2 diabetes patients

Impaired activation of mitochondrial energy metabolism in the presence of glucose has been demonstrated in pancreatic beta-cells from patients with type 2 diabetes. The cause of this dysfunction has been unknown. Publishing online in Endocrinology, Buck Institute assistant research professor Akos Gerencser, PhD, shows that in patients with type 2 diabetes the balance between supply and demand of the mitochondrial membrane potential (ΔψM) is altered causing a decrease in the signaling that turns on insulin secretion.

30 Jul 2015

Articles explore mechanisms of repetitive thinking that contributes to mental health, illness

The ability to engage in mental time travel -- to delve back into past events or imagine future outcomes -- is a unique and central part of the human experience. And yet this very ability can have detrimental consequences for both physical and mental well-being when it becomes repetitive and uncontrolled.

30 Jul 2015

Cancer Research UK scientists identify five distinct types of prostate cancer

Cancer Research UK scientists have for the first time identified that there are five distinct types of prostate cancer and found a way to distinguish between them, according to a landmark study published today in EBioMedicine.

30 Jul 2015

Smaller doses of resveratrol more effective at preventing bowel cancer

Resveratrol, a chemical found in red grapes, is more effective in smaller doses at preventing bowel cancer in mice than high doses, according to new research published today (Wednesday) in the journal Science Translational Medicine.

30 Jul 2015

Race to meet EU biofuel targets could put human health at risk

The race to meet carbon-neutral biofuel targets could put human health and food crop production at risk unless it is carefully planned, according to new research.

30 Jul 2015

Patients undergoing surgery for lung cancer wait too long to receive treatment, skip vital diagnostic steps

Patients undergoing surgery for lung cancer may wait too long to receive treatment, and too many patients skip vital diagnostic steps that are needed to help determine the best possible treatment, according to an article in the August 2015 issue of The Annals of Thoracic Surgery.

30 Jul 2015

Finding by UCSF researchers could increase availability of kidneys for transplant

Mild hypothermia in deceased organ donors significantly reduces delayed graft function in kidney transplant recipients when compared to normal body temperature, according to UC San Francisco researchers and collaborators, a finding that could lead to an increase in the availability of kidneys for transplant.

30 Jul 2015

Study reveals new way to help medical students learn about Alzheimer's disease

With the growing number of people with Alzheimer's disease, understanding their care is vital for doctors. Yet medical students often just learn the facts and may only see people with advanced disease who are at the hospital or nursing home. A study shows a new way to help medical students learn about the disease—at the art museum.

30 Jul 2015

Researchers identify link between individual characteristics and employment gap in people with disabilities

Researchers have explored the characteristics of people with disabilities who have achieved success in the workplace. The gap was found to be smaller among women, married people, individuals with higher educational achievement, Asians, and Hispanics, and people in their 20s and 60s.

30 Jul 2015

New study reports creation of genetic porcine model of cancer

With many types of cancers, early detection offers the best hope for survival. However, research into new early-detection screenings, as well as possible interventional radiology and surgical treatments, has been hindered by the lack of a large animal model that would accurately reflect the types of cancers seen in human cells.

30 Jul 2015

One sunburn increases risk of skin cancer by 50%

Everybody's got a story about that "one bad burn" - the time you fell asleep next to the pool and tattooed a white handprint on your lobster-red chest, or forgot to pack the sunscreen while hiking a Colorado 14er.

30 Jul 2015

Scientists study role of protein oxidation in the ageing process

Research published in the journal Cell Reports challenges the most popular theory about why our bodies deteriorate in old age. Scientists know that as we grow older our cells accumulate particles, called free radicals.

30 Jul 2015

Blocking the expression of certain gene reduces excessive fat in patients

By blocking the expression of a certain gene in patients, University of Montreal researchers have contributed to the demonstration of great decreases in the concentration of triglycerides in their blood, even in various severe forms of hypertriglyceridemia and regardless of the base values or the treatment the patient usually receives.

30 Jul 2015

UIC, Northwestern University researchers create first artificial ribosome

Researchers at the University of Illinois at Chicago and Northwestern University have engineered a tethered ribosome that works nearly as well as the authentic cellular component, or organelle, that produces all the proteins and enzymes within the cell. The engineered ribosome may enable the production of new drugs and next-generation biomaterials and lead to a better understanding of how ribosomes function.

30 Jul 2015

Low blood level of 4 proteins can help diabetics protect against immune attack

Patients with type 1 diabetes have significantly lower blood levels of four proteins that help protect their tissue from attack by their immune system, scientists report.

30 Jul 2015

Protecting gastrointestinal system during radiation or chemotherapy allows patients to tolerate cancer treatments

The stem cells in our gut divide so fast that they create a completely new population of epithelial cells every week. But this quick division is also why radiation and chemotherapy wreak havoc on the gastrointestinal systems of cancer patients - such therapies target rapidly dividing cells.

30 Jul 2015

People with IBD experience higher anxiety risk compared to peers without IBD

People who have inflammatory bowel disease (IBD), such as Crohn's disease or ulcerative colitis, have twice the odds of having a generalized anxiety disorder at some point in their lives when compared to peers without IBD, according to a new study published by University of Toronto researchers.

30 Jul 2015

Discovery could put individuals with relapsing UTIs on fast track for new therapeutic regimen

It's one thing to grow bacteria in a test tube, perform a screen in the lab, and find a mutation in the pathogen's genes. It's a whole other thing, and much rarer, to find the exact same mutation in nature--in this case, in E. coli in urine samples from some 500 patients suffering from relapsing urinary tract infections.

30 Jul 2015

Researchers demonstrate direct connection between NOX proteins and liver fibrosis

Researchers at the University of California, San Diego School of Medicine have demonstrated a direct connection between two signaling proteins and liver fibrosis, a scarring process underlying chronic liver disease, the 12th leading cause of death in the United States.

30 Jul 2015

Medical Research News

Commonly prescribed drug also lowers blood pressure when combined with diuretic

Bioenergetic analysis of pancreatic beta-cells shows impaired metabolic signature in type 2 diabetes patients

Articles explore mechanisms of repetitive thinking that contributes to mental health, illness

Cancer Research UK scientists identify five distinct types of prostate cancer

Smaller doses of resveratrol more effective at preventing bowel cancer

Race to meet EU biofuel targets could put human health at risk

Patients undergoing surgery for lung cancer wait too long to receive treatment, skip vital diagnostic steps

Finding by UCSF researchers could increase availability of kidneys for transplant

Study reveals new way to help medical students learn about Alzheimer's disease

Researchers identify link between individual characteristics and employment gap in people with disabilities

New study reports creation of genetic porcine model of cancer

One sunburn increases risk of skin cancer by 50%

Scientists study role of protein oxidation in the ageing process

Blocking the expression of certain gene reduces excessive fat in patients

UIC, Northwestern University researchers create first artificial ribosome

Low blood level of 4 proteins can help diabetics protect against immune attack

Protecting gastrointestinal system during radiation or chemotherapy allows patients to tolerate cancer treatments

People with IBD experience higher anxiety risk compared to peers without IBD

Discovery could put individuals with relapsing UTIs on fast track for new therapeutic regimen

Researchers demonstrate direct connection between NOX proteins and liver fibrosis

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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