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Bosutinib resistance linked to ABCB1 transporter

Resistance to the tyrosine kinase inhibitor bosutinib may be mediated by overexpression of the efflux transporter ABCB1, scientists suggest.

24 Jul 2015

Rare BCR-ABL fusions highlighted in CML

Chronic myeloid leukaemia patients with rare BCR-ABL fusions may be missed by quantitative polymerase chain reaction, research suggests.

24 Jul 2015

$Steroid-refractory chronic GVHD trial results ‘overestimate’ treatment efficacy$

Steroid-refractory chronic GVHD trial results ‘overestimate’ treatment efficacy

Trial results for patients with steroid-refractory chronic graft versus host have overestimated the efficacies of treatments, suggests a meta-analysis published in The Lancet Haematology.

24 Jul 2015

Diagnosing psychiatric disorder may not be as important as prescribing effective treatment

Nailing the diagnosis of a psychiatric disorder may not be important in prescribing effective treatment, according to Mark Zimmerman, M.D., a clinical researcher at Rhode Island Hospital. His opinion editorial was published online today in the Journal of Clinical Psychiatry.

24 Jul 2015

Study analyzes effect of shift work on prostate cancer

In a recent original article in Deutsches Ärzteblatt International (Dtsch Arztbl Int 112: 463-70), Gael P. Hammer et al. show that shift workers do not develop prostate cancer more frequently than their colleagues who work during the day.

24 Jul 2015

New mathematical simulation model helps manage ICU bed occupancy effectively

The critical care doctor Julio Barado-Hualde (Villava, Navarre, 1965) has developed a mathematical simulation model that enables the occupancy of beds in an ICU (Intensive Care Unit) to be predicted so that they can be managed more effectively. This research, which focusses on the Hospital Complex of Navarre, is part of his PhD thesis read at the NUP/UPNA-Public University of Navarre.

24 Jul 2015

York scientists identify how some micro-RNAs can make prostate cancers resistant to radiotherapy

Scientists at the University of York believe they have identified how some tiny regulatory molecules in cells can make prostate cancers resistant to radiotherapy.

24 Jul 2015

Adults born very premature display socially withdrawn personality

New research indicates that adults born very premature are more likely to be socially withdrawn and display signs of autism.

24 Jul 2015

New computer algorithm helps scientists see drug's activity inside the body

Researchers at Columbia University Medical Center have developed a computer algorithm that is helping scientists see how drugs produce pharmacological effects inside the body. The study, published in the journal Cell, could help researchers create drugs that are more efficient and less prone to side effects, suggest ways to regulate a drug's activity, and identify novel therapeutic uses for new and existing compounds.

24 Jul 2015

New study reveals protein's critical role in development and progression of AML

A new study by researchers at University of California, San Diego School of Medicine reveals a protein's critical - and previously unknown -- role in the development and progression of acute myeloid leukemia (AML), a fast-growing and extremely difficult-to-treat blood cancer.

24 Jul 2015

V-PPRN approved to receive $1.4 million to participate in second phase of PCORnet

The Vasculitis Patient-Powered Research Network, led by Peter A. Merkel, MD, MPH, Professor of Medicine and Epidemiology at the University of Pennsylvania and George Casey, MBA, Vice President of the Vasculitis Foundation, has been approved to receive a three-year $1.4 million award by the Patient-Centered Outcomes Research Institute as part of the second phase of the National Patient-Centered Clinical Research Network.

24 Jul 2015

U of T researchers discover DNA ambulance

U of T researchers have discovered how severely damaged DNA is transported within a cell and how it is repaired.

24 Jul 2015

Factors linked with increased risk of falling identified in patients with COPD

In a recent year-long study, 40% of patients with chronic obstructive pulmonary disease (COPD) experienced falls, with more than 75% of these falling multiple times.

24 Jul 2015

Computerized attention-control training program significantly reduces PTSD symptoms among combat veterans

A computerized attention-control training program significantly reduced combat veterans' preoccupation with - or avoidance of -- threat and attendant PTSD symptoms. By contrast, another type of computerized training, called attention bias modification - which has proven helpful in treating anxiety disorders - did not reduce PTSD symptoms. NIMH and Israeli researchers conducted parallel trials in which the two treatments were tested in US and Israeli combat veterans.

24 Jul 2015

Vanderbilt researchers hope to give new dexterity to needlescopic surgery with tiny mechanical wrist

With the flick of a tiny mechanical wrist, a team of engineers and doctors at Vanderbilt University's Medical Engineering and Discovery Laboratory hope to give needlescopic surgery a whole new degree of dexterity.

24 Jul 2015

Breakthrough reveals influence of schizophrenia’s 'Rosetta Stone' gene in brain development

Scientists have identified a critical function of what they believe to be schizophrenia's "Rosetta Stone" gene that could hold the key to decoding the function of all genes involved in the disease.

24 Jul 2015

Researchers question benefits of deworming intervention in school-age children

Deworming children may not improve school attendance and the evidence that informs international policy needs to be re-appraised following a major re-analysis by researchers at the London School of Hygiene & Tropical Medicine.

24 Jul 2015

Mix of bacteria living in guts may band together to ward off dangerous infections

Like a collection of ragtag villagers fighting off an invading army, the mix of bacteria that live in our guts may band together to keep dangerous infections from taking hold, new research suggests.

24 Jul 2015

Men more likely to suffer from cannabis psychosis compared to women

New research by health scientists at the University of York has revealed that a greater proportion of men than women suffer from cannabis psychosis.

24 Jul 2015

Researchers find way to reverse clotting factor deficiency that triggers hemophilia A

Sufferers of hemophilia live in a perpetual state of stress and anxiety: their joints wear down prematurely and they have bleeding episodes that feel like they will never end. Their bodies lack the ability to make the clotting factor responsible for the coagulation of blood so any cut or bruise can turn into an emergency without immediate treatment.

24 Jul 2015

Medical Research News

Bosutinib resistance linked to ABCB1 transporter

Rare BCR-ABL fusions highlighted in CML

Steroid-refractory chronic GVHD trial results ‘overestimate’ treatment efficacy

Diagnosing psychiatric disorder may not be as important as prescribing effective treatment

Study analyzes effect of shift work on prostate cancer

New mathematical simulation model helps manage ICU bed occupancy effectively

York scientists identify how some micro-RNAs can make prostate cancers resistant to radiotherapy

Adults born very premature display socially withdrawn personality

New computer algorithm helps scientists see drug's activity inside the body

New study reveals protein's critical role in development and progression of AML

V-PPRN approved to receive $1.4 million to participate in second phase of PCORnet

U of T researchers discover DNA ambulance

Factors linked with increased risk of falling identified in patients with COPD

Computerized attention-control training program significantly reduces PTSD symptoms among combat veterans

Vanderbilt researchers hope to give new dexterity to needlescopic surgery with tiny mechanical wrist

Breakthrough reveals influence of schizophrenia’s 'Rosetta Stone' gene in brain development

Researchers question benefits of deworming intervention in school-age children

Mix of bacteria living in guts may band together to ward off dangerous infections

Men more likely to suffer from cannabis psychosis compared to women

Researchers find way to reverse clotting factor deficiency that triggers hemophilia A

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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