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Antibiotic resistance potentially threatens the safety and efficacy of surgical procedures and immunosuppression therapies

This week The Lancet Infectious Diseases journal published the strongest evidence to date that increasing antibiotic resistance could have disastrous consequences for patients undergoing surgery or cancer chemotherapy. Based on a review of published literature, researchers predict that a 30% reduction in the efficacy of the prophylactic antibiotics routinely given when these procedures are performed could result in 120,000 more infections and 6300 infection-related deaths every year in the USA alone.

16 Oct 2015

Glutamate imaging may guide surgery in ‘nonlesional’ epilepsy

Glutamate imaging may be capable of identifying the focus of epileptic seizures in patients who appear to have nonlesional epilepsy on standard imaging techniques, researchers report in Science Translational Medicine.

16 Oct 2015

Seizure control improves for TSC patients undergoing more extensive surgery

Children with the genetic disorder tuberous sclerosis complex (TSC) often need epilepsy surgery for severe, uncontrollable seizures. A new study finds that seizure control is improved for patients undergoing more extensive surgery, reports the October issue of Neurosurgery, official journal of the Congress of Neurological Surgeons, published by Wolters Kluwer.

16 Oct 2015

Study: Young Latinos in rural areas face discrimination when obtaining health care services

Young Latinos living in rural areas say they face discrimination when they obtain health care services - a factor that could contribute to disparities in their rates for obtaining medical care and in their health outcomes, a new study from Oregon State University has found.

16 Oct 2015

Hiroshima University researchers demonstrate how Sendai virus escapes host immune system

A research group at Hiroshima University demonstrated the mechanism by which the Sendai virus (SeV) escapes the host immune system. The researchers examined the crystal structure of the complex of SeV C protein and transcription factor STAT1, and found that SeV C protein inhibits the signal transduction pathway of interferon gamma.

16 Oct 2015

Study reveals gene mutation that increases risk of SUDEP in patients with mild forms of disease

Researchers in the Adult Genetic Epilepsy Program of the Krembil Neuroscience Centre have discovered a gene mutation that increases the risk of sudden unexpected death in epilepsy (SUDEP) in patients with mild forms of the disease.

16 Oct 2015

WSU scientist wins federal grant to explore metabolism pathways, tobacco carcinogens

A Washington State University researcher has received a $2.6 million federal grant to study the body's ability to keep tobacco smoke components from causing cancer.

16 Oct 2015

Analysis of high-throughput sequencing data reveals new genes linked to chronic lymphocytic leukemia

Johannes Reiter, former PhD student in the group of Krishnendu Chatterjee at the Institute of Science and Technology Austria (IST Austria), is co-author of a Nature paper on genetic alterations that drive the progression and relapse of cancer.

16 Oct 2015

New breakthrough advances our understanding of how brain detects, prevents dehydration

Scientists at the Research Institute of the McGill University Health Centre (RI-MUHC) and Duke University have made a breakthrough that advances our understanding of how the brain detects and prevents dehydration.

16 Oct 2015

Rare genetic mutation could improve outcomes in NSCLC patients with brain metastases

Most patients with non-small cell lung cancer (NSCLC) that has metastasized to the brain have a dire prognosis. But Yale researchers have identified a subset of those patients with a rare genetic mutation who are living significantly longer than patients without the mutation.

16 Oct 2015

Study shows vitamin D, calcium supplements fail to protect against colorectal cancer

A large, randomized study at 11 U.S. hospitals including Dartmouth-Hitchcock Medical Center found that vitamin D and calcium supplements fail to protect against developing colorectal cancer.

16 Oct 2015

Set of genes identified in human genome essential for survival, proliferation of human cell lines

Using two complementary analytical approaches, scientists at Whitehead Institute and Broad Institute of MIT and Harvard have for the first time identified the universe of genes in the human genome essential for the survival and proliferation of human cell lines or cultured human cells.

16 Oct 2015

Safe, effective douche-based rectal microbicide can prevent HIV in gay men

Enemas are commonly used by men who have sex with men (MSM) and transwomen (TW) before sexual intercourse. But these groups are vulnerable to HIV and a host of other sexually transmitted infections because enemas -- even those that use tap water -- can seriously damage the thin tissue lining the rectum, allowing for easier transmission of harmful viruses and bacteria.

16 Oct 2015

Researchers create high resolution images of telomerase that plays major role in cancer, aging

An enzyme called telomerase plays a significant role in aging and most cancers, but until recently many aspects of the enzyme's structure could not be clearly seen.

16 Oct 2015

Study identifies proteins that could help in treating deafness

Almost 40 million Americans suffer from hearing loss. Right now, there is no way to reverse this condition, largely because auditory hair cells, which sense sound and relay that information to the brain, do not regenerate.

16 Oct 2015

New synthetic process helps study key molecule involved in diabetes, inflammation, aging

A synthetic process developed at Yale University will allow researchers to study a key molecule involved in diabetes, inflammation, and human aging.

16 Oct 2015

Binge drinking leads to higher number of deaths, continues to drain US economy

Excessive alcohol use continues to be a drain on the American economy, according to a study released by the Centers for Disease Control and Prevention (CDC). Excessive drinking cost the U.S. $249 billion in 2010, or $2.05 per drink, a significant increase from $223.5 billion, or $1.90 per drink, in 2006.

16 Oct 2015

Study suggests combination of MMF and CNIs can protect against rare lymphoma

A study led by Johns Hopkins researchers has linked the immunosuppressive drug mycophenolate mofetil (MMF) to an increased risk of central nervous system (CNS) lymphoma in solid organ transplant patients.

16 Oct 2015

Study shows why cancer anemia therapy stimulates tumor growth

Scientists have shown why a drug widely used to treat chemotherapy-induced anemia in ovarian and breast cancer patients also may shorten survival times in some patients by inadvertently stimulating tumor growth.

16 Oct 2015

Genomic analysis confirms sexual transmission of Ebola virus in Liberia

A suspected case of sexual transmission of Ebola virus disease (EVD) in Liberia was confirmed using genomic analysis, thanks to in-country laboratory capabilities established by U.S. Army scientists in collaboration with the Liberian Institute for Biomedical Research (LIBR).

16 Oct 2015

Medical Research News

Antibiotic resistance potentially threatens the safety and efficacy of surgical procedures and immunosuppression therapies

Glutamate imaging may guide surgery in ‘nonlesional’ epilepsy

Seizure control improves for TSC patients undergoing more extensive surgery

Study: Young Latinos in rural areas face discrimination when obtaining health care services

Hiroshima University researchers demonstrate how Sendai virus escapes host immune system

Study reveals gene mutation that increases risk of SUDEP in patients with mild forms of disease

WSU scientist wins federal grant to explore metabolism pathways, tobacco carcinogens

Analysis of high-throughput sequencing data reveals new genes linked to chronic lymphocytic leukemia

New breakthrough advances our understanding of how brain detects, prevents dehydration

Rare genetic mutation could improve outcomes in NSCLC patients with brain metastases

Study shows vitamin D, calcium supplements fail to protect against colorectal cancer

Set of genes identified in human genome essential for survival, proliferation of human cell lines

Safe, effective douche-based rectal microbicide can prevent HIV in gay men

Researchers create high resolution images of telomerase that plays major role in cancer, aging

Study identifies proteins that could help in treating deafness

New synthetic process helps study key molecule involved in diabetes, inflammation, aging

Binge drinking leads to higher number of deaths, continues to drain US economy

Study suggests combination of MMF and CNIs can protect against rare lymphoma

Study shows why cancer anemia therapy stimulates tumor growth

Genomic analysis confirms sexual transmission of Ebola virus in Liberia

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

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