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Women with Type 2 diabetes face barrier to physical activity

Women with Type 2 diabetes experience a barrier to physical activity that threatens to make them more sedentary and cause their health to worsen, according to a new study by Amy Huebschmann, MD, MS of the University of Colorado Anschutz Medical Campus.

15 Oct 2015

Developing tailored interventions for cognitive and behavioral symptoms key to improving outcomes after TBI

Kessler researchers assessed moderate to severe traumatic brain injury (TBI) for frontal behavioral syndromes and cognitive function. Their finding suggest that adding the Frontal Systems Behavior Scale to neuropsychological assessment may yield useful information about the behavioral sequelae of TBI.

15 Oct 2015

Researchers report weak association between brain size and IQ

As early as 1836, the German physiologist and anatomist Friedrich Tiedemann, in an article in the Philosophical Transactions, expressed his opinion that "there is undoubtedly a connection between the absolute size of the brain and the intellectual powers and functions of the mind". With the advent of brain imaging methods (e.g., MRI, PET), reliable assessments of in-vivo brain volume and investigations of its association with IQ are now possible.

15 Oct 2015

Drug interactions in placenta may increase risk of birth defects or stunting fetal growth

To date, studies in pregnant women examining transport of drugs across the placenta are rare and inadequate, said Tomo Nabekura, PhD. Such knowledge could be vital to preserving fetal health. In a new laboratory study, Nabekura and colleagues have illuminated a piece of this puzzle, and the results hint that mothers taking new anti-hepatitis C and/or anti-HIV drugs along with anti-hypertensives or non-steroidal anti-inflammatories (NSAIDs) could be raising the risk of birth defects or stunting fetal growth, respectively.

15 Oct 2015

Perimenopausal women at greater risk for developing insomnia

Millions of women may likely be sleep-deprived. It's already a known fact that women are more predisposed to insomnia. Now a new study presented at the 2015 Annual Meeting of The North American Menopause Society earlier this month suggests that perimenopausal women have an even greater risk for developing insomnia. Considering that perimenopause will affect roughly 500 million women within the next decade, that's a lot of tired women.

15 Oct 2015

Gene therapy preserves vision in canine model of late-stage retinitis pigmentosa

Gene therapy preserved vision in a study involving dogs with naturally occurring, late-stage retinitis pigmentosa, according to research funded by the National Eye Institute (NEI), part of the National Institutes of Health. The findings contribute to the groundwork needed to move gene therapy forward into clinical trials for people with the blinding eye disorder, for which there is currently no cure.

15 Oct 2015

Poorly-designed animal study threatens validity of preclinical research

Badly designed studies may lead to the efficacy of drugs being overestimated and money being wasted on trials that prove fruitless, according to new a study from McGill University in Canada.

15 Oct 2015

Specific gene signature could help predict survival outcomes among children with intermediate-risk RMS

Among children with intermediate-risk rhabdomyosarcoma (RMS) that is negative for a fusion gene, those who had a high score of a specific gene signature called MG5 had poorer survival outcomes compared with those who had a low score of MG5.

15 Oct 2015

Computers can be as good as doctors and nurses in predicting patient discharges

A computer can do as good a job of predicting how many patients will be discharged from a hospital unit on a given day as doctors and nurses can, according to new research from the University of Maryland's Robert H. Smith School of Business and Johns Hopkins University. In some cases, the computer does even better.

15 Oct 2015

UTHealth biochemists expose structures of IP3R calcium channels

Calcium is a crucial element in the body that controls thought, movement and other bodily functions. These events are directed by specialized proteins called ion channels that allow the flow of calcium ions in and out of cells and among cell compartments. For years, scientists have been unsure how calcium ion channels function.

15 Oct 2015

CWRU investigator receives $2.82 million NIH grant to make stealth bombs for brain cancer treatment

A Case Western Reserve University researcher has received a 5-year, $2.82 million National Institutes of Health grant to make, in essence, stealth bombs that slip past the brain's defenses to attack an incurable form of cancer.

15 Oct 2015

Only few doctors refer children with developmental delays to genetics specialists, say researchers

A nine-month-old boy isn't rolling over, reaching for objects or babbling as he should be. One step his doctor won't likely take right away: have him evaluated by a genetics specialist.

15 Oct 2015

New blood test could help pair cancer patients with suitable therapy for their disease

CANCER RESEARCH UK-funded scientists have developed a blood test that could help pair cancer patients with the most suitable therapy for their disease and then track the tumour's progress to see if the treatment is working, according to research published today (Thursday) in Clinical Cancer Research.

15 Oct 2015

Having a high stress job may increase risk of stroke

Having a high stress job may be linked to a higher risk of stroke, according to an analysis of several studies. The meta-analysis is published in the October 14, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

15 Oct 2015

Bio-molecules present in human breast milk can help resolve inflammation, combat infection

Human breast milk, which provides essential nutrients and antibodies to newborns, has long been known to play an important role in infant development and the immune system. In a new study published in Mucosal Immunology, researchers from Brigham and Women's Hospital report that human breast milk serves as a reservoir for bio-molecules that help to resolve inflammation and combat infection.

15 Oct 2015

New $6.7 million project aims to help kidney dialysis patients live longer

Helping kidney dialysis patients have healthier treatment sessions and longer lives is the goal of a new $6.7 million project at the University of Michigan.

15 Oct 2015

Novel ligand peptide-mimic inhibits abnormal overgrowth of blood vessels, may lead to new anti-cancer drugs

An international research team led by scientists at the University of New Mexico Cancer Center discovered and developed a novel ligand peptide-mimic that inhibits abnormal overgrowth of blood vessels in retinal diseases and tumors. The discovery could lead to new drugs that keep cancers from growing. The team published a paper in the journal Science Translational Medicine.

15 Oct 2015

Different Crohn's disease treatments affect children's gut microbes in distinct ways

Different treatments for Crohn's disease in children affects their gut mi-crobes in distinct ways, which has implications for future development of microbial-targeted therapies for these patients, according to a study led by researchers from the Perelman School of Medicine at the University of Pennsylvania.

15 Oct 2015

Researchers link organ transplant drug to rise in rare lymphoma

A study led by Johns Hopkins researchers has linked the immunosuppressive drug mycophenolate mofetil (MMF) to an increased risk of central nervous system (CNS) lymphoma in solid organ transplant patients. But the same study also found that another class of immunosuppressive drugs, called calcineurin inhibitors (CNIs), given alone or in combination with MMF, appears to protect transplant patients against this rare form of lymphoma.

15 Oct 2015

Ebola virus can linger in semen of some men nine months after onset of symptoms

Preliminary results of a study into persistence of Ebola virus in body fluids show that some men still produce semen samples that test positive for Ebola virus nine months after onset of symptoms.

15 Oct 2015

Medical Research News

Women with Type 2 diabetes face barrier to physical activity

Developing tailored interventions for cognitive and behavioral symptoms key to improving outcomes after TBI

Researchers report weak association between brain size and IQ

Drug interactions in placenta may increase risk of birth defects or stunting fetal growth

Perimenopausal women at greater risk for developing insomnia

Gene therapy preserves vision in canine model of late-stage retinitis pigmentosa

Poorly-designed animal study threatens validity of preclinical research

Specific gene signature could help predict survival outcomes among children with intermediate-risk RMS

Computers can be as good as doctors and nurses in predicting patient discharges

UTHealth biochemists expose structures of IP3R calcium channels

CWRU investigator receives $2.82 million NIH grant to make stealth bombs for brain cancer treatment

Only few doctors refer children with developmental delays to genetics specialists, say researchers

New blood test could help pair cancer patients with suitable therapy for their disease

Having a high stress job may increase risk of stroke

Bio-molecules present in human breast milk can help resolve inflammation, combat infection

New $6.7 million project aims to help kidney dialysis patients live longer

Novel ligand peptide-mimic inhibits abnormal overgrowth of blood vessels, may lead to new anti-cancer drugs

Different Crohn's disease treatments affect children's gut microbes in distinct ways

Researchers link organ transplant drug to rise in rare lymphoma

Ebola virus can linger in semen of some men nine months after onset of symptoms

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

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