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Synaptic plasticity alterations responsible for memory impairment in Alzheimer's disease

Neurons communicate with one another by synaptic connections, where information is exchanged from one neuron to its neighbor. These connections are not static, but are continuously modulated in response to the ongoing activity (or experience) of the neuron. This process, known as synaptic plasticity, is a fundamental mechanism for learning and memory in humans as in all animals.

27 Jan 2016

Young adults who use social media more likely to suffer sleep disturbances

Young adults who spend a lot of time on social media during the day or check it frequently throughout the week are more likely to suffer sleep disturbances than their peers who use social media less, according to new research from the University of Pittsburgh School of Medicine.

27 Jan 2016

Laser-based fabrication method reduces costs for cancer screening and research

In a move that slashes 90 percent of the cost of mass-producing metastatic microtumors and therapeutic microtissues for screening and research, Rice University bioengineers have adapted techniques from the "maker" movement to reprogram a commercial laser cutter to etch up to 50,000 tiny "microwells" per hour into sheets of silicone.

27 Jan 2016

Genes that influence people's health also have impact on some cognitive functions

Genes that influence people's health also shape how effectively they think, a study shows. Scientists found that genes associated with diseases including Alzheimer's disease, schizophrenia, and autism also have an impact on some cognitive functions.

27 Jan 2016

Air pollution exposure increases preterm birth risk

Exposure to high levels of small particle air pollution is associated with an increased risk of preterm birth - before 37 weeks of pregnancy, according to a new study published online in the journal Environmental Health.

27 Jan 2016

Early diagnosis, treatment of sleep apnea may reduce hospital readmissions for heart failure patients

Early diagnosis and treatment of sleep apnea may reduce six-month readmissions for patients hospitalized with heart failure, according to research recently published online by the American Journal of Cardiology.

27 Jan 2016

University of Leicester researchers publish structural details of protein linked to many types of cancer

A team from the University of Leicester has for the first time published a detailed description of a protein linked to many types of cancer.

27 Jan 2016

E-cigarettes suppress immune defenses, alter inflammation and boost bacterial virulence

Researchers at the University of California, San Diego School of Medicine and Veterans Affairs San Diego Healthcare System report data suggesting that e-cigarettes are toxic to human airway cells, suppress immune defenses and alter inflammation, while at the same time boosting bacterial virulence.

27 Jan 2016

UI researchers uncover how cancer cells form tumors

Two University of Iowa studies offer key insights by recording in real time, and in 3-D, the movements of cancerous human breast tissue cells. It's believed to be the first time cancer cells' motion and accretion into tumors has been continuously tracked.

27 Jan 2016

Children with sensory processing disorder have altered pathways for brain connectivity

Researchers at UC San Francisco have found that boys and girls with sensory processing disorder (SPD) have altered pathways for brain connectivity when compared to typically developing children, and the difference predicts challenges with auditory and tactile processing.

27 Jan 2016

Study identifies potential therapeutic targets for treatment of multiple sclerosis

Treatment of multiple sclerosis (MS) and other inflammatory diseases may benefit by new findings from a study that identified potential therapeutic targets for a devastating disease striking some 2.3 million people worldwide.

26 Jan 2016

Researchers identify three single-driver genetic alterations that occur in neuroepithelial tumors

The St. Jude Children's Research Hospital – Washington University Pediatric Cancer Genome Project (PCGP) has identified critical driver genes that account for disease-related alterations in a range of uncommon low-grade neuroepithelial tumors.

26 Jan 2016

Using Single-Molecule Studies to Understand Cellular Processes: An Interview with Professor W. E. Moerner

Single fluorescent molecules provide a local nanometer-sized probe of complex systems. We can measure the motion of the single molecule, use them to achieve imaging on a scale down to 20 nanometers, or we can infer aspects of the behaviour of the object under study by the details of the light that is emitted.

From Pittcon 26 Jan 2016

Monitoring HBcrAg levels could help optimise PEG-IFN therapy

Serum hepatitis B core-related antigen could serve as a quantitative marker of response to pegylated interferon therapy in patients with chronic hepatitis B virus infection positive for hepatitis B e antigen (HBeAg), findings indicate.

26 Jan 2016

Rescue TDF monotherapy effective in multidrug resistant chronic HBV

Researchers from the Republic of Korea say that rescue therapy with tenofovir disoproxil fumarate alone is an appropriate option for patients with multidrug resistant chronic hepatitis B virus infection.

26 Jan 2016

Palonosetron effective anti-emetic for paediatric chemotherapy patients

Palonosetron 20 μg/kg is noninferior to ondansetron for the control of chemotherapy-induced vomiting and nausea during the acute phase of the first treatment cycle in paediatric patients with cancer, research shows.

26 Jan 2016

STAT4 variant predicts HBV IFNα response

Variation in the STAT4 gene is associated with response to interferon (IFN)α therapy in patients with hepatitis B e antigen-positive chronic hepatitis B virus infection, suggests research published in Hepatology.

26 Jan 2016

The mechanism behind protective cells protecting themselves

Researchers at St. Jude Children's Research Hospital have discovered the mechanism by which immune cells called regulatory T cells keep themselves intact and functional during their demanding task of holding the immune system in check. Such T cells are key to preventing the immune system from attacking the body in autoimmune disease.

26 Jan 2016

Using acidity to detect cancer

Normally, tissues demonstrate a slightly acidic intracellular pH (pHi) and slightly alkaline extracellular pH (pHe). However, proliferating tissues demonstrate transient pH Gradient Reversal i.e. alkalinization of pHi and acidification of pHe.

26 Jan 2016

Preventing memory loss in Alzheimer's Disease, a new key mechanism

26 Jan 2016

Medical Research News

Synaptic plasticity alterations responsible for memory impairment in Alzheimer's disease

Young adults who use social media more likely to suffer sleep disturbances

Laser-based fabrication method reduces costs for cancer screening and research

Genes that influence people's health also have impact on some cognitive functions

Air pollution exposure increases preterm birth risk

Early diagnosis, treatment of sleep apnea may reduce hospital readmissions for heart failure patients

University of Leicester researchers publish structural details of protein linked to many types of cancer

E-cigarettes suppress immune defenses, alter inflammation and boost bacterial virulence

UI researchers uncover how cancer cells form tumors

Children with sensory processing disorder have altered pathways for brain connectivity

Study identifies potential therapeutic targets for treatment of multiple sclerosis

Researchers identify three single-driver genetic alterations that occur in neuroepithelial tumors

Using Single-Molecule Studies to Understand Cellular Processes: An Interview with Professor W. E. Moerner

Monitoring HBcrAg levels could help optimise PEG-IFN therapy

Rescue TDF monotherapy effective in multidrug resistant chronic HBV

Palonosetron effective anti-emetic for paediatric chemotherapy patients

STAT4 variant predicts HBV IFNα response

The mechanism behind protective cells protecting themselves

Using acidity to detect cancer

Preventing memory loss in Alzheimer's Disease, a new key mechanism

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