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Long-term lithium exposure does not increase renal dysfunction risk

Stable lithium maintenance therapy does not increase the risk of renal dysfunction in patients with bipolar affective disorder, findings from a population-based study suggest.

14 Oct 2015

enGene, Janssen Biotech sign agreement to develop and commercialize new IBD therapies

enGene, Inc. a gene therapy company focused on development of therapeutics using its proprietary "Gene Pill" and enema gene delivery platform, today announced that it has entered into a definitive agreement with Janssen Biotech, Inc., one of the Janssen Pharmaceutical Companies of Johnson & Johnson, to develop and commercialize new therapies for inflammatory bowel disease (IBD).

14 Oct 2015

UVA researchers receive $1.9 million NIH grant to prevent heart failure

Could your heart get hooked on blood sugar? Researchers at the University of Virginia School of Medicine think so, and they will determine if blocking that addiction could prevent enlargement of the heart that can lead to deadly heart failure.

14 Oct 2015

Notch activation determines signals necessary to generate hematopoietic stem cells in laboratory

An international study led by researchers from IMIM (Hospital del Mar Medical Research Institute) published in the journal Nature Communications has revealed that the intensity or efficiency of the activation of a protein called Notch, which is involved in the different phases of embryonic development, determines the fate of cells, i.e. if cells will form the aorta artery or blood (hematopoietic) stem cells. For artery cells, many Notch molecules need to be activated, whereas for hematopoietic cells many fewer are needed.

14 Oct 2015

Researchers identify molecular switch that can avoid inflammation

Our immune system is vital to us and can sometimes overreact causing chronic illnesses, such as for instance rheumatism and allergy. Now, researchers from Umeå University and University of Gothenburg have identified a molecular switch - MYSM1 - that can suppress such an overreaction and avoid inflammation.

14 Oct 2015

Antipsychotic drugs more frequently used in Alzheimer's disease patients, new study finds

Antipsychotic drugs are initiated in patients with Alzheimer's disease (AD) more frequently than in the general population - already 2-3 years before the Alzheimer's diagnosis, according to a new study from the University of Eastern Finland.

14 Oct 2015

New hope for patients with Duchenne muscular dystrophy

New hope for Duchenne muscular dystrophy (DMD) patients. A mouse genetic study in PLoS Medicine reports that targeting the P2RX7 gene, a purinoreceptor, may halt the progression of DMD.

14 Oct 2015

Researchers one step closer to finding effective drug for alcohol dependence

Researchers at Karolinska Institutet and the Sahlgrenska Academy in Sweden might be one step closer to finding an effective drug for alcohol dependence. In two separate studies, they show that the so-called dopamine stabilizer OSU6162 can reduce the craving for alcohol in alcohol dependent people and normalises the level of dopamine in the brain reward system of rats that have consumed alcohol over a long period of time.

14 Oct 2015

Thyroid hormone treatment improves cardiac health in female rats with high blood pressure

Thyroid hormones administered to female rats with high blood pressure led to encouraging cardiac improvements, according to a study in the American Journal of Physiology led by NYIT College of Osteopathic Medicine researcher Martin Gerdes.

14 Oct 2015

Researchers come up with new design for a better liposome

Using computational modeling, researchers at Carnegie Mellon University, the Colorado School of Mines and the University of California, Davis have come up with a design for a better liposome. Their findings, while theoretical, could provide the basis for efficiently constructing new vehicles for nanodrug delivery.

14 Oct 2015

Sense oligonucleotide antidote reverses actions of antisense antithrombotic drug, prevents bleeding

Researchers from Isis Pharmaceuticals (Carlsbad, CA) and Prysis Biotechnologies (Pudong, Shanghai, China) have demonstrated proof-of-concept for using a sense oligonucleotide to undo the effects of an antisense drug, an antithrombotic agent in this novel study.

14 Oct 2015

Diabetic patients who use nurse practitioners for primary care have lower rates of preventable hospitalization

New research from The University of Texas Medical Branch at Galveston indicates that diabetic patients who got their primary care from nurse practitioners did not have an increase in potentially preventable hospital admissions.

14 Oct 2015

Researchers match certain schizophrenia symptoms to features of the brain's anatomy

Using advanced brain imaging, researchers have matched certain behavioral symptoms of schizophrenia to features of the brain's anatomy. The findings, at Washington University School of Medicine in St. Louis, could be a step toward improving diagnosis and treatment of schizophrenia.

14 Oct 2015

Insulin dose not independent risk factor for cardiovascular death

A NIH-sponsored double-blinded, randomized clinical trial entitled Action to Control Cardiovascular Risk in Diabetes (ACCORD study) came to a halt seven years ago after patients receiving more intensive diabetes therapy were found to have a higher mortality rate, compared to the standard therapy.

14 Oct 2015

Head injuries, traumatic experiences and mental illness higher among severe polyinhalant users

Incarcerated youth who have suffered head injuries, traumatic experiences and mental illness diagnoses are more likely to abuse multiple inhalants, according to researchers at Georgia State University and the University of North Carolina at Chapel Hill.

14 Oct 2015

First-ever genomic study shows dengue may survive year-round in southern China

The first-ever comprehensive genomic analysis of the virus that causes dengue fever suggests that it may survive year-round in southern China.

14 Oct 2015

Researchers find significant link between breast cancer and nutrition, explore new preventative treatment

Researchers at Sydney’s Centenary Institute are working on a new treatment aimed at “starving” breast cancer cells, following the discovery of a significant link between breast cancer and nutrition.

14 Oct 2015

Researchers identify new therapeutic target for Duchenne muscular dystrophy

Scientists have found what could one day lead to a promising treatment for those with a crippling disease, Duchenne muscular dystrophy.

14 Oct 2015

Introduction of Ebola treatment beds reduces large number of deaths, Ebola cases in Sierra Leone

The introduction of thousands of Ebola treatment beds by the UK and Sierra Leone governments and NGOs prevented an estimated 57,000 Ebola cases and 40,000 deaths in Sierra Leone, according to new research published in the Proceedings of the National Academy of Sciences.

14 Oct 2015

Clinical study results of VolitionRx's NuQ test for pancreatic cancer published in Clinical Epigenetics

VolitionRx Limited today announced that full results from a completed clinical study of its NuQ blood-based test for early stage pancreatic cancers have been published in the online issue of Clinical Epigenetics, the official journal of the Clinical Epigenetics Society.

14 Oct 2015

Medical Research News

Long-term lithium exposure does not increase renal dysfunction risk

enGene, Janssen Biotech sign agreement to develop and commercialize new IBD therapies

UVA researchers receive $1.9 million NIH grant to prevent heart failure

Notch activation determines signals necessary to generate hematopoietic stem cells in laboratory

Researchers identify molecular switch that can avoid inflammation

Antipsychotic drugs more frequently used in Alzheimer's disease patients, new study finds

New hope for patients with Duchenne muscular dystrophy

Researchers one step closer to finding effective drug for alcohol dependence

Thyroid hormone treatment improves cardiac health in female rats with high blood pressure

Researchers come up with new design for a better liposome

Sense oligonucleotide antidote reverses actions of antisense antithrombotic drug, prevents bleeding

Diabetic patients who use nurse practitioners for primary care have lower rates of preventable hospitalization

Researchers match certain schizophrenia symptoms to features of the brain's anatomy

Insulin dose not independent risk factor for cardiovascular death

Head injuries, traumatic experiences and mental illness higher among severe polyinhalant users

First-ever genomic study shows dengue may survive year-round in southern China

Researchers find significant link between breast cancer and nutrition, explore new preventative treatment

Researchers identify new therapeutic target for Duchenne muscular dystrophy

Introduction of Ebola treatment beds reduces large number of deaths, Ebola cases in Sierra Leone

Clinical study results of VolitionRx's NuQ test for pancreatic cancer published in Clinical Epigenetics

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

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