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UConn researchers sequence RNA of most complicated gene

UConn researchers have sequenced the RNA of the most complicated gene known in nature, using a hand-held sequencer no bigger than a cell phone.

From Oxford Nanopore Technologies 12 Oct 2015

Novel mathematical method may help reduce development of antibiotic-resistant bacteria

It is estimated that each year in the United States 2 million people become infected with bacteria that are resistant to one or more types of antibiotics, and at least 23,000 people will die because of these infections. This problem is being exacerbated by overuse of antibiotics for livestock and also in community clinical practice. This overuse, combined with the slow pace of novel drug discovery is a growing threat to public health.

12 Oct 2015

YK-4-279 compound works against some forms of leukemia: Study

A compound discovered and developed by a team of Georgetown Lombardi Comprehensive Cancer Center researchers that halts cancer in animals with Ewing sarcoma and prostate cancer appears to work against some forms of leukemia, too.

12 Oct 2015

Magnet hospitals have higher patient ratings of care than other hospitals

Patients' experience with healthcare has become the focal point for quality improvement among hospitals and care providers. The Affordable Care Act incentivizes hospitals to improve patient satisfaction by paying a financial incentive to hospitals that achieve high ratings from patients.

12 Oct 2015

Many early-stage breast cancer patients still not getting life-saving treatment, new study finds

Accelerated partial breast irradiation was designed to be a faster, more convenient, and potentially safer way for many women with breast cancer to reduce their mortality risk and help keep their cancer from returning after surgery. But a new study shows that the availability of the approach is failing to reduce the percentage of early-stage breast cancer patients who do not receive the radiation treatment that could save their lives.

12 Oct 2015

Discovery may help scientists to better predict how quickly HIV virus returns after patients stop treatment

Scientists are now better able to predict how quickly the HIV virus will return after individuals stop treatment following a discovery by researchers at UNSW Australia and the University of Oxford.

12 Oct 2015

Study looks at survival benefits of surgical resection for melanoma patients with abdominal metastases

Patients with metastatic melanoma who undergo surgery to remove lesions that have spread into the abdomen live more than twice as long as those treated with drug therapy alone, according to novel new research by a North Shore-LIJ Health System cancer surgeon.

12 Oct 2015

Suspicion of fetal size influences patient-provider decisions to perform certain perinatal interventions

Nearly one-third of women, without a prior cesarean, reported that they were told by their maternity care providers that their babies might be ''quite large," leading to higher rates of medically-induced labor or planned cesarean deliveries that may not be warranted, a new study co-authored by Boston University School of Public Health and Medicine researchers shows.

12 Oct 2015

Cancer survival outcomes can vary widely among U.S. hospitals

Decades of research have shown that cancer survival outcomes can vary widely depending on where patients receive care. But efforts to rank hospitals by long-term survival rates have been hindered by the readily available administrative data derived from Medicare claims, which lacks information about cancer stage. Two hospitals providing equally good care may have different survival rates if one hospital treats sicker patients, for example.

12 Oct 2015

Study reveals cost of inpatient hospitalizations caused by non-lethal FRIs and gun violence in the USA

A retrospective study reveals the cost of inpatient hospitalizations caused by non-lethal Firearm Related Injuries (FRIs) and gun violence in the USA at $679 million annually. The authors also found that FRIs disproportionately affects the young (18-24 year olds), poor and minority males (Hispanics and Blacks) in urban settings.

12 Oct 2015

Research finding offers hope for more powerful aspirin-like drugs

Researchers have found that salicylic acid targets the activities of HMGB1, an inflammatory protein associated with a wide variety of diseases, offering hope that more powerful aspirin-like drugs may be developed.

11 Oct 2015

FDA awards research grants to boost product development for patients with rare diseases

The U.S. Food and Drug Administration today announced it has awarded 18 new research grants totaling more than $19 million to boost the development of products for patients with rare diseases, which affect the lives of nearly 30 million Americans.

11 Oct 2015

Role for endogenous retrovirus proposed in ALS pathogenesis

Expression of the human endogenous retrovirus-K is upregulated in some patients with sporadic amyotrophic lateral sclerosis and causes degeneration of motor neurons when overexpressed in mice, research shows.

9 Oct 2015

Cognitive decline common and rapid in Parkinson’s patients

Researchers report that nearly half of patients with Parkinson’s disease (PD) develop cognitive impairment within about a decade, and progress rapidly to dementia.

9 Oct 2015

New test for heart attack may save NHS millions

A simple blood test could be used to rule out the possibility of heart attack in two-thirds of people who attend A&E with chest pains, report UK researchers.

9 Oct 2015

Scientists can now use skin samples from older patients to grow brain cells

For the first time, scientists can use skin samples from older patients to create brain cells without rolling back the youthfulness clock in the cells first. The new technique, which yields cells resembling those found in older people's brains, will be a boon to scientists studying age-related diseases like Alzheimer's and Parkinson's.

9 Oct 2015

Scientists calculate precise measurements of heritability in nine pediatric-onset autoimmune diseases

Scientists have calculated more precise measurements of heritability--the influence of underlying genes--in nine autoimmune diseases that begin in childhood. The research may strengthen researchers' abilities to better predict a child's risk for associated autoimmune diseases.

9 Oct 2015

Scientists engineer stem cells to better understand mechanisms behind leukemia

Scientists engineered stem cells to better understand the mechanisms behind a form of leukemia caused by changes in a key gene, according to a study led by Mount Sinai researchers and published online today in the journal Cell Reports.

9 Oct 2015

Artificial lung model could provide better understanding of health risks associated with airborne pollution

A life-sized artificial human lung created at the Technion-Israel Institute of Technology is the first diagnostic tool for understanding in real time how tiny particles move and behave in the deepest part of the human lungs (alveolar tissue).

9 Oct 2015

New analysis finds illogical thoughts as most predictive of schizophrenia risk

Despite decades of study, schizophrenia has remained stubbornly difficult to diagnose in its earliest stage - between the appearance of symptoms and the development of the disorder. Now, a new analysis led by researchers at the UNC School of Medicine and the Renaissance Computing Institute identified illogical thoughts as most predictive of schizophrenia risk.

9 Oct 2015

Medical Research News

UConn researchers sequence RNA of most complicated gene

Novel mathematical method may help reduce development of antibiotic-resistant bacteria

YK-4-279 compound works against some forms of leukemia: Study

Magnet hospitals have higher patient ratings of care than other hospitals

Many early-stage breast cancer patients still not getting life-saving treatment, new study finds

Discovery may help scientists to better predict how quickly HIV virus returns after patients stop treatment

Study looks at survival benefits of surgical resection for melanoma patients with abdominal metastases

Suspicion of fetal size influences patient-provider decisions to perform certain perinatal interventions

Cancer survival outcomes can vary widely among U.S. hospitals

Study reveals cost of inpatient hospitalizations caused by non-lethal FRIs and gun violence in the USA

Research finding offers hope for more powerful aspirin-like drugs

FDA awards research grants to boost product development for patients with rare diseases

Role for endogenous retrovirus proposed in ALS pathogenesis

Cognitive decline common and rapid in Parkinson’s patients

New test for heart attack may save NHS millions

Scientists can now use skin samples from older patients to grow brain cells

Scientists calculate precise measurements of heritability in nine pediatric-onset autoimmune diseases

Scientists engineer stem cells to better understand mechanisms behind leukemia

Artificial lung model could provide better understanding of health risks associated with airborne pollution

New analysis finds illogical thoughts as most predictive of schizophrenia risk

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

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