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Proposed thin-plate model sheds light on structural basis of chromosomal aberrations in cancer cells

During cell division, each metaphase chromosome contains a single enormously long DNA molecule that is associated with histone proteins and forms a long chromatin filament with many nucleosomes.

9 Oct 2015

HDL not so good in protecting women against atherosclerosis, study shows

What has previously been known as good cholesterol--high density lipoprotein (HDL)--has now been shown to be not so good in protecting women against atherosclerosis while they are transitioning through menopause. That's according to a new study from the University of Pittsburgh Graduate School of Public Health that was presented last week at the annual meeting of The North American Menopause Society in Las Vegas.

9 Oct 2015

Scientists map EGFRvIII mutant that causes brain cancer

A team of Ludwig Cancer Research scientists has mapped out how a mutant version of the epidermal growth factor receptor (EGFR) known as EGFRvIII specifically drives critical processes that alter the reading of the genome to fuel the growth of the brain cancer glioblastoma multiforme (GBM) and--most important--how each process is linked to the other.

9 Oct 2015

Gene therapy prevents neuronal death, disease effects in experimental model of PD

An estimated seven to ten million people worldwide are living with Parkinson's disease (PD), which is an incurable and progressive disease of the nervous system affecting movement and cognitive function. More than half of PD patients develop progressive disease showing signs of dementia similar to Alzheimer's disease.

9 Oct 2015

Father’s life experiences can affect health, development of both children and grandchildren

If you have diabetes, or cancer or even heart problems, maybe you should blame it on your dad's behaviour or environment. Or even your grandfather's.

9 Oct 2015

Study: Learning complex auditory categories through procedural learning is impaired in dyslexia

The cognitive skills used to learn how to ride a bike may be the key to a more accurate understanding of developmental dyslexia. And, they may lead to improved interventions.

9 Oct 2015

Mysterious kidney disease may be caused by chronic dehydration tied to global climate change

A mysterious kidney disease that has killed over 20,000 people in Central America, most of them sugar cane workers, may be caused by chronic, severe dehydration linked to global climate change, according to a new study by Richard J. Johnson, MD, of the University of Colorado Anschutz Medical Campus.

9 Oct 2015

Research shows sex change hormonal treatment also changes brain chemistry

Hormonal treatments administered as part of the procedures for sex reassignment have well-known and well-documented effects on the secondary sexual characteristics of the adult body, shifting a recipient's physical appearance to that of the opposite sex.

9 Oct 2015

Pitt research team awarded NIH grant to study impact of substance abuse on adolescent brain development

A research team in the department of psychiatry, at the University of Pittsburgh, has been awarded a $5 Million National Institutes of Health grant to participate in a multi-site study focusing on the impact of adolescent marijuana, alcohol and other drug use on the developing brain.

9 Oct 2015

Researchers reveal new subtypes of invasive lobular carcinoma

Researchers from the UNC Lineberger Comprehensive Cancer Center and other academic centers have revealed new subtypes of invasive lobular carcinoma, the second most commonly diagnosed invasive breast cancer type. The findings could lead to personalized treatment approaches for the disease.

9 Oct 2015

Study confirms neuroprotective effects of hypothermia in newborns with HIE

A unique study at Children's Hospital Los Angeles of newborns treated with hypothermia for hypoxic-ischemic encephalopathy (HIE) - a condition that occurs when the brain is deprived of an adequate oxygen supply - confirms its neuroprotective effects on the brain.

9 Oct 2015

Research finding could lead to new treatments for celiac disease

A team of researchers has discovered that bacteria found in the gut may contribute to the body's response to gluten, an important finding that could lead to new treatments for celiac disease.

9 Oct 2015

Roy D. Patterson selected to receive ASA's Silver Medal in Psychological and Physiological Acoustics

Roy D. Patterson, Emeritus Professor at the University of Cambridge, Cambridge, UK, has been named recipient of the Acoustical Society of America's Silver Medal in Psychological and Physiological Acoustics for contributions to understanding pitch and timbre perception, and for computational modeling of auditory representations.

9 Oct 2015

Light-chain amyloidosis patients treated with high-dose chemo and stem cell transplantation have long-term survival

Patients with Light-chain (AL) amyloidosis who are treated with high-dose chemotherapy (melphalan) and autologous (one's own) stem cell transplantation (HDM/SCT) have the greatest success for long-term survival.

9 Oct 2015

ED physicians make key changes in clinical decision-making after viewing CT scan results

A study from the Massachusetts General Hospital Institute for Technology assessment finds that, after viewing CT scan results, physicians in the emergency departments of four major academic medical centers made key changes in clinical decision-making for patients with symptoms frequently seen in emergency rooms.

9 Oct 2015

Brain & Behavior Research Foundation to honor nine scientists with Outstanding Achievement Prizes

The Brain & Behavior Research Foundation will honor nine scientists with its 2015 Outstanding Achievement Prizes for their work in schizophrenia, mood disorders, child and adolescent psychiatry, and cognitive neuroscience.

9 Oct 2015

Scientists create first 3-D image of key protein involved in development of cancers

Scientists from New Zealand and Australia have created the first three-dimensional image of a key protein involved in the development of blood and other cancers.

9 Oct 2015

Manchester researchers demonstrate safety, effectiveness of eltrombopag treatment in children with ITP

Researchers in Manchester have demonstrated for the first time the relative safety and effectiveness of treatment, eltrombopag, in children with persistent or chronic immune thrombocytopenia (ITP), as part of an international duo of studies.

9 Oct 2015

New study examines factors that may protect transgender individuals from attempting suicide

The likelihood of a transgender person attempting suicide is very high, often because of the prejudice, transphobia and other stressors he or she may experience. A new study examined factors that may protect transgender adults from attempting suicide. Its conclusions also inform medical and mental health professionals who work with transgender clients.

9 Oct 2015

BMC awarded NIDDK grant to study outcomes of minority women receiving diabetes self-management education

The National Institute of Diabetes and Digestive and Kidney Diseases has awarded a $783,906 grant to Suzanne Mitchell, MD, a family physician at Boston Medical Center, to study health outcomes of minority women with type 2 diabetes who participate in group medical visits to help them manage their diabetes.

9 Oct 2015

Medical Research News

Proposed thin-plate model sheds light on structural basis of chromosomal aberrations in cancer cells

HDL not so good in protecting women against atherosclerosis, study shows

Scientists map EGFRvIII mutant that causes brain cancer

Gene therapy prevents neuronal death, disease effects in experimental model of PD

Father’s life experiences can affect health, development of both children and grandchildren

Study: Learning complex auditory categories through procedural learning is impaired in dyslexia

Mysterious kidney disease may be caused by chronic dehydration tied to global climate change

Research shows sex change hormonal treatment also changes brain chemistry

Pitt research team awarded NIH grant to study impact of substance abuse on adolescent brain development

Researchers reveal new subtypes of invasive lobular carcinoma

Study confirms neuroprotective effects of hypothermia in newborns with HIE

Research finding could lead to new treatments for celiac disease

Roy D. Patterson selected to receive ASA's Silver Medal in Psychological and Physiological Acoustics

Light-chain amyloidosis patients treated with high-dose chemo and stem cell transplantation have long-term survival

ED physicians make key changes in clinical decision-making after viewing CT scan results

Brain & Behavior Research Foundation to honor nine scientists with Outstanding Achievement Prizes

Scientists create first 3-D image of key protein involved in development of cancers

Manchester researchers demonstrate safety, effectiveness of eltrombopag treatment in children with ITP

New study examines factors that may protect transgender individuals from attempting suicide

BMC awarded NIDDK grant to study outcomes of minority women receiving diabetes self-management education

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

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