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Nucleoporin proteins play significant role in maintaining embryonic stem cells

What if you found out that pieces of your front door were occasionally flying off the door frame to carry out chores around the house? That's the kind of surprise scientists at the Salk Institute experienced with their recent discovery that nucleoporins -- proteins that act as cellular 'doorways' to help manage what goes in and out of a cell's nucleus -- are actually much bigger players in expressing genes than previously thought.

19 Jun 2015

HUJI professor honored with Helmholtz International Fellow Award for epigenetics research

The Israeli immunologist and cancer researcher Professor Yehudit Bergman of the Hebrew University of Jerusalem, Israel, has been honored with the Helmholtz International Fellow Award for her excellent research. In a prize ceremony at the MDC Max Delbrück Center for Molecular Medicine in the Helmholtz Association in Berlin, Germany, MDC's interim director Professor Thomas Sommer presented the certificate to her on Thursday, June 18th, 2015.

19 Jun 2015

UB study sheds light on the molecular basis of cocaine addiction

Researchers at the University at Buffalo have discovered a previously unknown neural pathway that can regulate changes made in the brain due to cocaine use, providing new insight into the molecular basis of cocaine addiction.

19 Jun 2015

Study shows 28% decline in prostate cancer diagnoses following USPSTF recommendation against PSA testing

A new study led by Vanderbilt University Medical Center investigators found new diagnoses of prostate cancer in the U.S. declined 28 percent in the year following the draft recommendation from the United States Preventive Services Task Force against routine PSA screening for men.

19 Jun 2015

Certain anti-nausea medications used after operation could increase risk for irregular heartbeat

Certain commonly prescribed anti-nausea medications given to patients during or after an operation could increase their risk of developing an irregular heartbeat, new research has found.

19 Jun 2015

Patient survival rates for home hemodialysis significantly higher than peritoneal dialysis

NxStage Medical, Inc. is encouraging patients to take control of their dialysis therapy and consider home hemodialysis in the wake of a new study that found patient survivability rates are significantly higher with home hemodialysis (HHD) than peritoneal dialysis (PD).

18 Jun 2015

Study identifies new biomarkers for prenatal risk assessment

NX Prenatal Inc., a privately held women's healthcare molecular diagnostic company, announced today that the American Journal of Perinatology has published the results of a blinded, retrospective study of 48 asymptomatic, healthy pregnant women that demonstrates the feasibility of assessing biomarkers associated with blood based microvesicles/exosomes for spontaneous preterm birth (SPTB) risk.

18 Jun 2015

EPFL scientists show how a major effector protein binds chromatin and regulates gene expression

Inside the cell, DNA is tightly coiled and packed with several proteins into a structure called "chromatin", which allows DNA to fit in the cell while also preventing genes from being expressed at the wrong time. Guided by a chemical "barcode", specialized effector proteins can bind chromatin and either unwind it or compact further to activate or silence genes.

18 Jun 2015

NIH researchers develop 'placenta-on-a-chip' to study role of placenta in pregnancy

National Institutes of Health researchers and their colleagues have developed a "placenta-on-a-chip" to study the inner workings of the human placenta and its role in pregnancy. The device was designed to imitate, on a micro-level, the structure and function of the placenta and model the transfer of nutrients from mother to fetus. This prototype is one of the latest in a series of organ-on-a-chip technologies developed to accelerate biomedical advances.

18 Jun 2015

Researchers track down key gene mutation responsible for causing acute lymphoblastic leukemia

Two medical researchers from the Children's Hospital of Michigan and the Wayne State University School of Medicine have published the results of a nearly 10-year investigation that identified a key gene mutation that can trigger acute lymphoblastic leukemia, or ALL, and several other types of cancer.

18 Jun 2015

Scientists reveal new combination method that efficiently destroys cancer cells

Scientists at the Institut Pasteur and Inserm have successfully increased the infiltration of immune cells into tumors, thus inducing the immune system to block tumor growth. In an article published in Nature Immunology, the scientists show that, in combination with existing immunotherapies, this process efficiently destroys cancer cells.

18 Jun 2015

Researchers find new way to potentially stop progression of late-stage cancers

An international research team led by Mayo Clinic oncologists has found a new way to identify and possibly stop the progression of many late-stage cancers, including bladder, blood, bone, brain, lung and kidney.

18 Jun 2015

Many people with type 2 diabetes also suffer from hypoglycaemia

Researchers from the University of Leicester and Leicester's Hospitals have discovered that many people suffering from type 2 diabetes also suffer from low blood sugar levels that can pose a significant risk to their health.

18 Jun 2015

Scientists create new model to study latent HIV infection in brain cells

Over 35 million people worldwide are currently infected by HIV. Antiviral therapies can keep the virus from multiplying. However, no drug can cure infection so far, because various cell types continue to carry the virus in a latent, i.e. quiescent, state. Scientists of Helmholtz Zentrum München have now established a model for latent HIV infection of brain cells.

18 Jun 2015

NIBIB-funded researcher develops new technique for tissue analysis

An NIBIB-funded researcher has developed a new technique that creates digital pictures of a tissue's chemical composition using light and a computer. The technique replaces the need for dyes or stains, which can be costly and require significant time and effort to apply.

18 Jun 2015

Researchers highlight important factors that impact early-stage breast cancer patients' access to BCT

The first comprehensive national review of breast-conserving therapy (BCT) shows that over the last 13 years rates of this treatment modality for early-stage breast cancer have increased at a steady pace. However, the review also highlights important demographic factors that impact which patients have access to BCT.

18 Jun 2015

Single difference in HIV's genetic code influences progression of disease

In a finding that furthers the understanding of human immunodeficiency virus (HIV), researchers from Children's Hospital Los Angeles discovered two locations where a single difference in HIV's genetic code altered the way the virus infected the cell, thereby influencing the progression of the disease.

18 Jun 2015

Higher consumption of dietary trans fatty acids may affect memory

Higher consumption of dietary trans fatty acids (dTFA), commonly used in processed foods to improve taste, texture and durability, has been linked to worsened memory function in men 45 years old and younger, according to a University of California, San Diego School of Medicine study published online on June 17 in PLOS ONE.

18 Jun 2015

Vinculin protein levels increase with age to alter shape, performance of cardiac muscle cells

The human heart makes precious few new cells but manages to generate billions of life-sustaining beats as it grows old.

18 Jun 2015

Early menstrual cycle could play role in development of ER-negative breast cancer among African-American women

Early age at menarche, or first menstrual cycle, could play a role in the disproportionate incidence of estrogen receptor (ER)-negative breast cancers diagnosed among African-American women, according to a study published in the Journal of the National Cancer Institute.

18 Jun 2015

Medical Research News

Nucleoporin proteins play significant role in maintaining embryonic stem cells

HUJI professor honored with Helmholtz International Fellow Award for epigenetics research

UB study sheds light on the molecular basis of cocaine addiction

Study shows 28% decline in prostate cancer diagnoses following USPSTF recommendation against PSA testing

Certain anti-nausea medications used after operation could increase risk for irregular heartbeat

Patient survival rates for home hemodialysis significantly higher than peritoneal dialysis

Study identifies new biomarkers for prenatal risk assessment

EPFL scientists show how a major effector protein binds chromatin and regulates gene expression

NIH researchers develop 'placenta-on-a-chip' to study role of placenta in pregnancy

Researchers track down key gene mutation responsible for causing acute lymphoblastic leukemia

Scientists reveal new combination method that efficiently destroys cancer cells

Researchers find new way to potentially stop progression of late-stage cancers

Many people with type 2 diabetes also suffer from hypoglycaemia

Scientists create new model to study latent HIV infection in brain cells

NIBIB-funded researcher develops new technique for tissue analysis

Researchers highlight important factors that impact early-stage breast cancer patients' access to BCT

Single difference in HIV's genetic code influences progression of disease

Higher consumption of dietary trans fatty acids may affect memory

Vinculin protein levels increase with age to alter shape, performance of cardiac muscle cells

Early menstrual cycle could play role in development of ER-negative breast cancer among African-American women

This International Women’s Day, Meet the Scientist Changing Women’s Healthcare

Microphysiological systems in drug discovery

Considerations for taking ASO discovery programs into animal models

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