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Researchers develop user-friendly platform for analyzing transcriptomic and epigenomic big data

Researchers at Cincinnati Children's Hospital Medical Center have developed a user-friendly, integrated platform for analyzing the transcriptomic and epigenomic "big data."

12 Aug 2015

Study finds no added benefit for insulin degludec and liraglutide in type 2 diabetes

The fixed-ratio combination of the two drugs insulin degludec and liraglutide (trade name: Xultophy) has been approved since September 2014 for adults with type 2 diabetes mellitus. It is given as an injection in addition to other blood-glucose lowering drugs when these alone or in combination with basal insulin are insufficient to lower blood glucose levels.

12 Aug 2015

Researchers discover way to prevent flu infection without any help from the virus

Researchers have discovered a way to trigger a preventive response to a flu infection without any help from the usual players - the virus itself or interferon, a powerful infection fighter.

12 Aug 2015

Dartmouth researcher finds way to predict human emotions

A Dartmouth researcher and his colleagues have discovered a way to predict human emotions based on brain activity.

12 Aug 2015

Ion channel blockers prove useful in cancer therapy

Drugs called ion channel blockers, which are commonly used to treat cardiac, neurological, and psychiatric disorders, might prove useful in cancer therapy, according to research findings in fruit flies and mice by UC San Francisco scientists that led to unconventional treatment of a case of metastatic brain cancer.

12 Aug 2015

Study looks at attention abilities of babies born through caesarean sections

Being delivered through a caesarean section influences at least one form of babies' ability to concentrate. It slows their spatial attention, which plays a role in how well they are able to prioritize and focus on a particular area or object that is of interest. These are the findings of Scott Adler and Audrey Wong-Kee-You of York University in Canada, published in Springer's journal Attention, Perception, & Psychophysics.

12 Aug 2015

Gastric bypass surgery enhances energy expenditure

Gastric bypass surgery often leads to a sustained weight loss. Researchers at Sahlgrenska Academy have found part of the explanation: the operation enhances energy expenditure such that eating actually helps the person lose weight.

12 Aug 2015

Researcher study potential biomarker to determine patients at risk for aggressive breast cancer

Biomarkers are an important part in detecting certain cancers such as the BRCA gene in breast cancer and the PSA antigen in prostate cancer. They are easy to identify in a blood test and can help in diagnosing and giving a prognosis.

12 Aug 2015

Insulin pump users face less risk of dying from cardiovascular disease

People with type 1 diabetes who use insulin pump therapy face almost 50% less risk of dying from cardiovascular disease than those who take insulin by multiple daily injections. The British Medical Journal has published a study conducted at Sahlgrenska Academy.

12 Aug 2015

Risk of hepatobiliary cancer higher in women with intrahepatic cholestasis of pregnancy

In a new study of more than 125,000 pregnant women in Sweden, researchers at the Sahlgrenska Academy found that the risk of hepatobiliary cancer and immune-mediated and cardiovascular diseases later in life is higher in women with intrahepatic cholestasis of pregnancy (ICP) than in women without this condition.

12 Aug 2015

Only 1 in 4 patients with ESRD in Georgia referred for kidney transplant evaluation

Only about one in four patients with end-stage renal disease in Georgia were referred for kidney transplant evaluation within 1 year of starting dialysis between 2005 and 2011, although there was substantial variability in referral among dialysis facilities, according to a study in the August 11 issue of JAMA.

12 Aug 2015

NYU Polytechnic School of Engineering researcher awarded grant to advance protein hydrogels that mimic nature

The U.S. Army Research Laboratory's Army Research Office recently awarded a New York University Polytechnic School of Engineering researcher a grant to advance protein-engineered, environmentally responsive hydrogels that could replicate biochemical processes currently found only in nature. These protein hydrogels could become fundamental building blocks of important new biomimetic materials.

12 Aug 2015

Study sheds light on what motivates people to trust

Trust matters whether it's love, money or another part of our everyday lives that requires risk, and a new study by a Dartmouth brain researcher and his collaborators sheds light on what motivates people to make that leap of faith.

12 Aug 2015

New study reveals role of hydrogen sulfide gas in autoimmune disease

The immune system not only responds to infections and other potentially problematic abnormalities in the body, it also contains a built-in brake in the form of regulatory T cells, or Tregs. Tregs ensure that inflammatory responses don't get out of hand and do damage. In autoimmune diseases, sometimes these Treg cells don't act as they should.

12 Aug 2015

Study: Chickenpox vaccination increases incidence of shingles in younger adults

Vaccinating one-year-olds against chickenpox could temporarily nearly double the incidence of shingles in the wider population, but in younger adults than previously thought.

12 Aug 2015

Scientists identify molecular pathway that can contribute to vision loss in macular degeneration

Scientists have identified a pathway that leads to the formation of atypical blood vessels that can cause blindness in people with age-related macular degeneration.

12 Aug 2015

New study launched to find impact of vasculitis on employment, income

The Vasculitis Patient-Powered Research Network and the Vasculitis Clinical Research Consortium launched a study entitled "Impact of vasculitis on employment and income" or "VascWork." The purpose of this study is to learn about the impact of vasculitis on employment and income in patients with different systemic vasculitides.

12 Aug 2015

Single incidence of abortion or miscarriage may impact subsequent pregnancies in women's lives

It has been well established that women who have had several abortions or miscarriages are likely to face a slightly higher risk of complications in subsequent pregnancies. They may experience vaginal bleeding during early pregnancy, preterm birth, low fetal birth weight, and placenta-related complications. Women with a medical history of several interrupted pregnancies are usually advised to take extra precautions to ensure healthy full-term pregnancies later in life.

12 Aug 2015

$Breakdown of fibrin protein essential for bone fracture repair$

Breakdown of fibrin protein essential for bone fracture repair

A team of Vanderbilt investigators has discovered that fibrin, a protein that was thought to play a key role in fracture healing, is not required. Instead, the breakdown of fibrin is essential for fracture repair.

12 Aug 2015

IQWiG dossier assessment finds no added benefit for vortioxetine in depression

Vortioxetine (trade name: Brintellix) has been approved since December 2013 for the treatment of depression in adults, but did not become actually available before May 2015. The German Institute for Quality and Efficiency in Health Care examined in a dossier assessment whether this drug offers an added benefit over the appropriate comparator therapy. Such an added benefit cannot be derived from the dossier because it contained no data evaluable for the assessment.

12 Aug 2015

Medical Research News

Researchers develop user-friendly platform for analyzing transcriptomic and epigenomic big data

Study finds no added benefit for insulin degludec and liraglutide in type 2 diabetes

Researchers discover way to prevent flu infection without any help from the virus

Dartmouth researcher finds way to predict human emotions

Ion channel blockers prove useful in cancer therapy

Study looks at attention abilities of babies born through caesarean sections

Gastric bypass surgery enhances energy expenditure

Researcher study potential biomarker to determine patients at risk for aggressive breast cancer

Insulin pump users face less risk of dying from cardiovascular disease

Risk of hepatobiliary cancer higher in women with intrahepatic cholestasis of pregnancy

Only 1 in 4 patients with ESRD in Georgia referred for kidney transplant evaluation

NYU Polytechnic School of Engineering researcher awarded grant to advance protein hydrogels that mimic nature

Study sheds light on what motivates people to trust

New study reveals role of hydrogen sulfide gas in autoimmune disease

Study: Chickenpox vaccination increases incidence of shingles in younger adults

Scientists identify molecular pathway that can contribute to vision loss in macular degeneration

New study launched to find impact of vasculitis on employment, income

Single incidence of abortion or miscarriage may impact subsequent pregnancies in women's lives

Breakdown of fibrin protein essential for bone fracture repair

IQWiG dossier assessment finds no added benefit for vortioxetine in depression

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