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CHLA scientists grow tissue-engineered small intestine from human cells

A new study by researchers at Children's Hospital Los Angeles has shown that tissue-engineered small intestine grown from human cells replicates key aspects of a functioning human intestine. The tissue-engineered small intestine they developed contains important elements of the mucosal lining and support structures, including the ability to absorb sugars, and even tiny or ultra-structural components like cellular connections.

9 Jan 2015

Increased UV radiation can affect human fertility, new NTNU study finds

A new study from the Norwegian University of Science and Technology shows that increased UV radiation can have an effect on human fertility over generations.

9 Jan 2015

Latest wearable tracking devices alone may not change health behavior, say Penn researchers

New Year's weight loss resolutions are in full swing, but despite all the hype about the latest wearable tracking devices, there's little evidence that this technology alone can change behavior and improve health for those that need it most, according to a new online-first viewpoint piece in JAMA.

9 Jan 2015

Man-made insulin nasal spray may improve memory in adults with Alzheimer's-related dementia

A man-made form of insulin delivered by nasal spray may improve working memory and other mental capabilities in adults with mild cognitive impairment and Alzheimer's disease dementia, according to a pilot study led by researchers at Wake Forest Baptist Medical Center.

9 Jan 2015

Researchers to explore physical, psychological effects of ultra-endurance running

In the upcoming Race Across USA, ultra-endurance athletes will run a marathon a day as they cover 3,080 miles from California to Maryland.

8 Jan 2015

Exposure to nanoparticles can play major role in development of cardiovascular diseases

Nanoparticles, extremely tiny particles measured in billionths of a meter, are increasingly everywhere, and especially in biomedical products. Their toxicity has been researched in general terms, but now a team of Israeli scientists has for the first time found that exposure nanoparticles (NPs) of silicon dioxide (SiO2) can play a major role in the development of cardiovascular diseases when the NP cross tissue and cellular barriers and also find their way into the circulatory system.

8 Jan 2015

One cup of blueberries per day could help reduce blood pressure, arterial stiffness

Just one cup of blueberries per day could be the key to reducing blood pressure and arterial stiffness, both of which are associated with cardiovascular disease.

8 Jan 2015

Researchers report that weight-reducing bariatric surgery fuels job discrimination

People say that they would be more likely to hire someone who has lost weight through exercise and dieting than through surgery. This is just one of the stigmas faced by obese people who undergo weight-reducing bariatric surgery, reports Robert Carels of East Carolina University in the US and his team of researchers.

8 Jan 2015

Enzymes linked to diabetes, obesity play major roles in arthritis and leukemia

Enzymes linked to diabetes and obesity appear to play key roles in arthritis and leukemia, potentially opening up new avenues for treating these diverse diseases, according to new research at Washington University School of Medicine in St. Louis.

8 Jan 2015

Neuroscientists move one step closer to solving how learning and memory work

Researchers at Johns Hopkins have found out how a protein crucial to learning works: by removing a biochemical "clamp" that prevents connections between nerve cells in the brain from growing stronger.

8 Jan 2015

New opportunity for developing simple test to measure E2F4 activity in ER+ breast cancer patients

By looking at the expression levels of downstream genes of the regulators in breast cancer, investigators at Dartmouth Hitchcock's Norris Cotton Cancer Center, led by Chao Cheng, PhD, have identified a gene signature in E2F4 that is predictive of estrogen receptor positive (ER+) breast cancer.

8 Jan 2015

Better physical functioning associated with remission of general anxiety, PTSD symptoms

In a two-year longitudinal study involving 13 intensive care units in four U.S. hospitals, researchers found that better physical functioning — basic and complex activities considered essential for maintaining independence — is associated with remission of general anxiety and post-traumatic stress disorder (PTSD) symptoms. These findings may help clinicians be better prepared for caring for the growing number of survivors of critical illness, potentially leading to a better quality of recovery for patients.

8 Jan 2015

Johns Hopkins-led study offers strategy to eradicate HIV

Luring dormant HIV out of hiding and destroying its last cure-defying holdouts has become the holy grail of HIV eradication, but several recent attempts to do so have failed. Now the findings of a Johns Hopkins-led study reveal why that is and offer a strategy that could form a blueprint for a therapeutic vaccine to eradicate lingering virus from the body.

8 Jan 2015

Improving headache treatment could reduce health care spending, new study suggests

Each year more than 12 million Americans visit their doctors complaining of headaches, which result in lost productivity and costs of upward of $31 billion annually. A new study by researchers from Beth Israel Deaconess Medical Center suggests some of that cost could be offset by physicians ordering fewer tests and an increased focus on counseling about lifestyle changes.

8 Jan 2015

Findings could accelerate development of prebiotic medicines for bowel problems, autoimmune diseases

Bacteria that have evolved to eat their way through yeast in the human gut could inform the development of new treatments for people suffering from bowel diseases.

8 Jan 2015

Research findings could lead to new drug design for neurological diseases

A new intermediate step and unexpected enzymatic activity in a metabolic pathway in the body, which could lead to new drug design for psychiatric and neurodegenerative diseases, has been discovered by researchers at Georgia State University.

8 Jan 2015

Testosterone therapy suppresses some advanced prostate cancers, find Johns Hopkins scientists

In a surprising paradox, the male hormone testosterone, generally thought to be a feeder of prostate cancer, has been found to suppress some advanced prostate cancers and also may reverse resistance to testosterone-blocking drugs used to treat prostate cancer.

8 Jan 2015

Protecting children in advance from head injuries helps reduce brain trauma

An exhaustive analysis of data from more than 40,000 cases of brain trauma in children - published by the authoritative New England Journal of Medicine - provides convincing evidence that protecting children in advance from head injuries is the key to reducing their severity.

7 Jan 2015

Study: Synthetic triglyceride oil may provide hope for people with Huntington's disease

An early study suggests that a synthetic triglyceride oil called triheptanoin may provide hope for people with Huntington's disease. The study is published in the January 7, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

7 Jan 2015

Using HIV drugs to treat AMD: an interview with Dr Mark Young

NRTIs are compounds which were originally developed in the 1960s as anti-cancer agents. They are similar in structure to the bases which make up DNA, and it was hoped that they would interfere with DNA replication in fast-growing cancer cells, slowing down or stopping tumour growth.

7 Jan 2015

Medical Research News

CHLA scientists grow tissue-engineered small intestine from human cells

Increased UV radiation can affect human fertility, new NTNU study finds

Latest wearable tracking devices alone may not change health behavior, say Penn researchers

Man-made insulin nasal spray may improve memory in adults with Alzheimer's-related dementia

Researchers to explore physical, psychological effects of ultra-endurance running

Exposure to nanoparticles can play major role in development of cardiovascular diseases

One cup of blueberries per day could help reduce blood pressure, arterial stiffness

Researchers report that weight-reducing bariatric surgery fuels job discrimination

Enzymes linked to diabetes, obesity play major roles in arthritis and leukemia

Neuroscientists move one step closer to solving how learning and memory work

New opportunity for developing simple test to measure E2F4 activity in ER+ breast cancer patients

Better physical functioning associated with remission of general anxiety, PTSD symptoms

Johns Hopkins-led study offers strategy to eradicate HIV

Improving headache treatment could reduce health care spending, new study suggests

Findings could accelerate development of prebiotic medicines for bowel problems, autoimmune diseases

Research findings could lead to new drug design for neurological diseases

Testosterone therapy suppresses some advanced prostate cancers, find Johns Hopkins scientists

Protecting children in advance from head injuries helps reduce brain trauma

Study: Synthetic triglyceride oil may provide hope for people with Huntington's disease

Using HIV drugs to treat AMD: an interview with Dr Mark Young

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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