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Strategy that dismantles flu viral genome in human lung cells ensures safe research

A new strategy that dismantles a viral genome in human lung cells will ensure safe research on deadly strains of influenza, say researchers from the Icahn School of Medicine at Mount Sinai.

13 Aug 2013

Emory’s Yerkes Research Center receives $9.5M grant to establish research center to study oxytocin

The Yerkes National Primate Research Center, Emory University, has received a five-year, $9.5 million grant from the National Institute of Mental Health (NIMH) to establish a Silvio O. Conte Center in Neuroscience Research to study oxytocin, a brain chemical known for forming bonds between mother and baby.

13 Aug 2013

Vitamin D supplementation does not improve blood pressure in hypertension patients

Vitamin D supplementation does not appear to improve blood pressure or markers of vascular health in older patients with isolated systolic hypertension (a common type of high blood pressure), according to a study by Miles D. Witham, Ph.D., of the University of Dundee, Scotland, United Kingdom, and colleagues.

13 Aug 2013

Cedars-Sinai launches Phase I clinical trial to study tolerability of immunization to treat Alzheimer's disease

Cedars-Sinai Medical Center has launched a Phase I clinical trial to study the safety and tolerability of an experimental immunization to treat Alzheimer's disease. The treatment is based on Copaxone (glatiramer acetate), a drug often prescribed to reduce the frequency of multiple sclerosis relapses.

13 Aug 2013

Patients with rare epilepsy aphasia share mutations on same gene

Some patients with a rare type of epilepsy called epilepsy aphasia have something else in common. They have mutations in the same gene. Epilepsy aphasia disorders are characterized by seizures and speech abnormalities.

13 Aug 2013

Bacterial strains that delay cell division might be used to design drugs that stop division entirely

In 1958 a group of scientists working in Denmark made the striking observation that bacterial cells are about twice as large when they are cultured on a rich nutrient source than when they are cultured on a meager one.

13 Aug 2013

Simple tests to recognize ability of famous people may help doctors identify early dementia

A new study suggests that simple tests that measure the ability to recognize and name famous people such as Albert Einstein, Bill Gates or Oprah Winfrey may help doctors identify early dementia in those 40 to 65 years of age.

13 Aug 2013

Researchers say type 2 diabetes status should be taken into account in future BMI-mortality studies

The relationship between body mass index (BMI) appears to be stronger in adults without diabetes than those with existing diabetes. These findings- are published in the Journal of General Internal Medicine- in a study by Chandra Jackson of the Harvard School of Public Health and colleagues.

13 Aug 2013

Researchers suggest neural stem cells may regenerate after anti-cancer treatment

Scientists have long believed that healthy brain cells, once damaged by radiation designed to kill brain tumors, cannot regenerate. But new Johns Hopkins research in mice suggests that neural stem cells, the body's source of new brain cells, are resistant to radiation, and can be roused from a hibernation-like state to reproduce and generate new cells able to migrate, replace injured cells and potentially restore lost function.

13 Aug 2013

Patients with IBS-D treated with eluxadoline achieve better clinical response

Patients with diarrhea-predominant irritable bowel syndrome, or IBS-D, treated with eluxadoline achieved better clinical response and experienced more symptom improvement than those using placebo, according to a recent study in Gastroenterology, the official journal of the American Gastroenterological Association. Eluxadoline, which is currently in phase 3 trials, is under development as a potential treatment for IBS-D.

13 Aug 2013

Harvard University receives grant to use organs-on-chips device to test human response to radiation

A team at the Wyss Institute for Biologically Inspired Engineering at Harvard University has received a $5.6 million grant award from the United States Food and Drug Administration (FDA) to use its Organs-on-Chips technology for a novel application of keen interest to national security and health officials: to test human physiological responses to radiation, and to evaluate drugs designed to counter those effects.

13 Aug 2013

Study provides clues to improve treatment of neuroblastoma with suppressor gene

Loss of a gene required for stem cells in the brain to turn into neurons may underlie the most severe forms of neuroblastoma, a deadly childhood cancer of the nervous system, according to a Ludwig Cancer Research study.

13 Aug 2013

Researchers explore potential of neural stem cells to repair brain damage

Scientists have long believed that healthy brain cells, once damaged by radiation designed to kill brain tumors, cannot regenerate. But new Johns Hopkins research in mice suggests that neural stem cells, the body’s source of new brain cells, are resistant to radiation, and can be roused from a hibernation-like state to reproduce and generate new cells able to migrate, replace injured cells and potentially restore lost function.

13 Aug 2013

Researchers create an efficient technique to target and repair defective genes

Using human pluripotent stem cells and DNA-cutting protein from meningitis bacteria, researchers from the Morgridge Institute for Research and Northwestern University have created an efficient way to target and repair defective genes.

13 Aug 2013

Adolescents with symptoms of depression also may be at risk for developing anxiety

Some adolescents who suffer with symptoms of depression also may be at risk for developing anxiety, according to a new study of children's mental health.

13 Aug 2013

Nuevolution forms scientific collaboration to investigate biological mechanism of GPCR drug target

Nuevolution A/S today announced that it has entered into a scientific collaboration with Duke University, the Howard Hughes Medical Institute, and Lexicon Pharmaceuticals, Inc. for the investigation of the biological mechanism of action of a specified GPCR drug target.

13 Aug 2013

Learning "grammar" helps determine whether gene gets switched on or not

Researchers have probed deep into the cell's genome, beyond the basic genetic code, to begin learning the "grammar" that helps determine whether or not a gene gets switched on to make the protein it encodes.

13 Aug 2013

School lunch consumption and TV viewing associated with childhood obesity

Among middle-school children, the behaviors most often linked with obesity are school lunch consumption and two hours or more of daily TV viewing, according to a new look at the dramatic increase in childhood obesity.

13 Aug 2013

Augmentation during childbirth appears to be linked with increased odds of autism

An analysis of North Carolina birth and educational records suggests that induction (stimulating uterine contractions prior to the onset of spontaneous labor) and augmentation (increasing the strength, duration, or frequency of uterine contractions with spontaneous onset of labor) during childbirth appears to be associated with increased odds of autism diagnosis in childhood, according to a study by Simon G. Gregory, Ph.D., of Duke University Medical Center, Durham, N.C., and colleagues.

13 Aug 2013

Healthy diet, moderate alcohol may be associated with decreased risk of CKD in diabetes patients

Eating a healthy diet and drinking a moderate amount of alcohol may be associated with decreased risk or progression of chronic kidney disease (CKD) in patients with type 2 diabetes mellitus, according to a report published by JAMA Internal Medicine, a JAMA Network publication.

13 Aug 2013

Medical Research News

Strategy that dismantles flu viral genome in human lung cells ensures safe research

Emory’s Yerkes Research Center receives $9.5M grant to establish research center to study oxytocin

Vitamin D supplementation does not improve blood pressure in hypertension patients

Cedars-Sinai launches Phase I clinical trial to study tolerability of immunization to treat Alzheimer's disease

Patients with rare epilepsy aphasia share mutations on same gene

Bacterial strains that delay cell division might be used to design drugs that stop division entirely

Simple tests to recognize ability of famous people may help doctors identify early dementia

Researchers say type 2 diabetes status should be taken into account in future BMI-mortality studies

Researchers suggest neural stem cells may regenerate after anti-cancer treatment

Patients with IBS-D treated with eluxadoline achieve better clinical response

Harvard University receives grant to use organs-on-chips device to test human response to radiation

Study provides clues to improve treatment of neuroblastoma with suppressor gene

Researchers explore potential of neural stem cells to repair brain damage

Researchers create an efficient technique to target and repair defective genes

Adolescents with symptoms of depression also may be at risk for developing anxiety

Nuevolution forms scientific collaboration to investigate biological mechanism of GPCR drug target

Learning "grammar" helps determine whether gene gets switched on or not

School lunch consumption and TV viewing associated with childhood obesity

Augmentation during childbirth appears to be linked with increased odds of autism

Healthy diet, moderate alcohol may be associated with decreased risk of CKD in diabetes patients

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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