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Study opens door to possible treatments for variety of mitochondrial diseases

By borrowing a tool from bacteria that infect plants, scientists have developed a new approach to eliminate mutated DNA inside mitochondria-the energy factories within cells. Doctors might someday use the approach to treat a variety of mitochondrial diseases, including the degenerative eye disease Leber hereditary optic neuropathy. The research, published online today in Nature Medicine, was funded by the National Eye Institute, a part of the National Institutes of Health.

5 Aug 2013

Vanderbilt University scientists discover new approach to treating mood, anxiety disorders

Chemically modified inhibitors of the COX-2 enzyme relieve anxiety behaviors in mice by activating natural "endocannabinoids" without gastrointestinal side effects, Vanderbilt University scientists will report next week.

5 Aug 2013

Researchers find vital enzyme complex that gets elevated in many cancers

A team of researchers from Philadelphia and Norway has determined the structure of an enzyme complex that modifies one end of most human proteins and is made at elevated levels in numerous forms of cancer. A study in Nature Structural & Molecular Biology, led by researchers at The Wistar Institute, depicts the structure and the means of action of a protein complex called NatA.

5 Aug 2013

Prothrombin complex concentrates more effective at reversing hemorrhage caused by warfarin

Prothrombin complex concentrates are faster and more effective than fresh frozen plasma at reversing hemorrhage caused by the anti-coagulant warfarin, despite plasma being the most commonly used therapy.

3 Aug 2013

New study explores pathways that lead to jail time for women

How do pathways to jail vary for females who are victims of specific types of trauma? New research published in Psychology of Women Quarterly, a SAGE journal, pinpoints the types of trauma such as caregiver violence, witnessing violence, and intimate partner violence, that lead to specific types of offending later in life and offers explanations based on real experiences.

3 Aug 2013

Necrostatin-1: A substance which counteracts several of aluminum's neurotoxic effects

New Studies in Mice Support Toxic Role of Aluminum in Neurodegenerative Conditions, According to Report in Restorative Neurology and Neuroscience

3 Aug 2013

Alcohol use increases risk of dopamine response in brain pathway

Research from McGill University suggests that people who are vulnerable to developing alcoholism exhibit a distinctive brain response when drinking alcohol, according to a new study by Prof. Marco Leyton, of McGill University's Department of Psychiatry.

3 Aug 2013

New study paves way for novel approaches to protect people from infections

A new study published by University of Utah researchers is paving the way for novel approaches related to how people are immunized to protect them from diseases.

3 Aug 2013

Plymouth researcher awarded Young Investigator Award by Children's Tumor Foundation

Dr. Lu Zhou, a member of a team of researchers at Plymouth University Peninsula Schools of Medicine and Dentistry whose area of expertise is brain tumours, has been awarded a fellowship by the Children's Tumor Foundation.

3 Aug 2013

HTR3 variants associated with effectiveness of ondansetron treatment for alcohol dependence

An experimental treatment for alcohol dependence works better in individuals who possess specific combinations of genes that regulate the function and binding of serotonin, a brain chemical affected by the treatment, according to a study supported by the National Institutes of Health. A report of the finding appears online in the American Journal of Psychiatry.

3 Aug 2013

Perceptions of children living with asthma may differ significantly from their caregivers

Children's perceptions of living with asthma may differ significantly from their caregivers' perceptions, which means both should be interviewed when they visit the doctor's office, a new study from UT Kids San Antonio and the Center for Airway Inflammation Research (cAIR) shows.

3 Aug 2013

Added benefit of thyroid cancer drug vandetanib not proven

Vandetanib (trade name: Caprelsa) has been approved in Germany since February 2012 for the treatment of adult patients who have a particular form of aggressive thyroid cancer. In a new benefit assessment, the German Institute for Quality and Efficiency in Health Care has now examined the added benefit of the drug pursuant to the Act on the Reform of the Market for Medicinal Products.

3 Aug 2013

New study explores connection between physical fights, cognitive decline

A new Florida State University study has found that adolescent boys who are hurt in just two physical fights suffer a loss in IQ that is roughly equivalent to missing an entire year of school. Girls experience a similar loss of IQ after only a single fighting-related injury.

3 Aug 2013

New findings could enable development of effective drugs for addiction with fewer side effects

Scientists from the Florida campus of The Scripps Research Institute have described findings that could enable the development of more effective drugs for addiction with fewer side effects.

3 Aug 2013

Study: Grape consumption linked with healthier dietary patterns, improved nutrient intakes

In a new observational study published in the Journal of Food Science, researchers looked at the association of grape consumption, in the non-alcoholic forms most commonly consumed - fresh grapes, raisins and 100% grape juice - with the diet quality of a recent, nationally representative sample of U.S. children and adults.

3 Aug 2013

New research may influence development of anti-viral therapies to fight against Dengue

New research into the fight against Dengue, an insect-borne tropical disease that infects up to 390 million people worldwide annually, may influence the development of anti-viral therapies that are effective against all four types of the virus.

3 Aug 2013

Burning incense generates indoor air pollutants that may cause inflammation in human lung cells

Burning incense, a popular cultural practice in Arabian Gulf countries and elsewhere, generates indoor air pollutants that may cause inflammation in human lung cells, say researchers in the Gillings School of Global Public Health at the University of North Carolina at Chapel Hill.

3 Aug 2013

New findings may lead to first new animal model for hepatitis C virus

By differentiating monkey stem cells into liver cells and inducing successful infection, researchers from the Icahn School of Medicine at Mount Sinai have shown for the first time that the hepatitis C virus can replicate in monkeys, according to research published in the journal Gastroenterology.

3 Aug 2013

Employees who work long hours with high job demands are more likely to develop depression

Employees who work long hours with high job demands are more likely to develop depression, suggests a study in the August Journal of Occupational and Environmental Medicine, official publication of the American College of Occupational and Environmental Medicine (ACOEM).

3 Aug 2013

Researchers identify specific behaviors that lead to compulsive buying

Why do shopping addicts keep spending even in the face of harmful financial, emotional and social consequences? A new study suggests poor credit management and a belief that new purchases will create a happier life fuel compulsive buying.

2 Aug 2013

Medical Research News

Study opens door to possible treatments for variety of mitochondrial diseases

Vanderbilt University scientists discover new approach to treating mood, anxiety disorders

Researchers find vital enzyme complex that gets elevated in many cancers

Prothrombin complex concentrates more effective at reversing hemorrhage caused by warfarin

New study explores pathways that lead to jail time for women

Necrostatin-1: A substance which counteracts several of aluminum's neurotoxic effects

Alcohol use increases risk of dopamine response in brain pathway

New study paves way for novel approaches to protect people from infections

Plymouth researcher awarded Young Investigator Award by Children's Tumor Foundation

HTR3 variants associated with effectiveness of ondansetron treatment for alcohol dependence

Perceptions of children living with asthma may differ significantly from their caregivers

Added benefit of thyroid cancer drug vandetanib not proven

New study explores connection between physical fights, cognitive decline

New findings could enable development of effective drugs for addiction with fewer side effects

Study: Grape consumption linked with healthier dietary patterns, improved nutrient intakes

New research may influence development of anti-viral therapies to fight against Dengue

Burning incense generates indoor air pollutants that may cause inflammation in human lung cells

New findings may lead to first new animal model for hepatitis C virus

Employees who work long hours with high job demands are more likely to develop depression

Researchers identify specific behaviors that lead to compulsive buying

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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