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Study reveals epigenetic mechanisms contribute to chronic disease susceptibility prior to birth

If you think stress is killing you, you may be right, but what you don't know is that stress might have harmed your health even before you were born. In a new report appearing in the August 2013 issue of The FASEB Journal, Harvard researchers find that epigenetic disruptions, which are associated with chronic disease later in life, are already common at birth.

2 Aug 2013

Trace substance in sugar improves muscle regeneration in mouse model with muscular dystrophy

A trace substance in caramelized sugar, when purified and given in appropriate doses, improves muscle regeneration in a mouse model of Duchenne muscular dystrophy. The findings are published today, Aug. 1, in the journal Skeletal Muscle.

2 Aug 2013

Study finds that tens of billions of dollars spent each year for moderate chronic kidney disease

Even early stages of kidney disease come with steep medical costs, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology. The study found that expenses related to moderate chronic kidney disease cost Medicare tens of billions of dollars each year.

2 Aug 2013

Research opens potential new avenue for cancer treatment

Scientists at The University of Texas MD Anderson who identified a protein's dual role in cancer promotion have discovered a way to shut it down, opening a potential new avenue for cancer treatment.

2 Aug 2013

Researchers show that JQ1 drug can block molecular pathway responsible for heart failure

Researchers from Case Western Reserve University School of Medicine and the Dana-Farber Cancer Institute have made a fundamental discovery relevant to the understanding and treatment of heart failure - a leading cause of death worldwide. The team discovered a new molecular pathway responsible for causing heart failure and showed that a first-in-class prototype drug, JQ1, blocks this pathway to protect the heart from damage.

2 Aug 2013

Omega-3 fatty acids can be used for treatment, prevention of skin and oral cancers: Research

Omega-3 fatty acids, contained in oily fish such as salmon and trout, selectively inhibit growth and induce cell death in early and late-stage oral and skin cancers, according to new research from scientists at Queen Mary, University of London.

2 Aug 2013

UCLA researchers develop treatment approach for breast cancer metastasized to brain

Researchers at UCLA's Jonsson Comprehensive Cancer Center (JCCC) have successfully combined cellular therapy and gene therapy in a mouse model system to develop a viable treatment strategy for breast cancer that has metastasized, or spread, to the patient's brain.

2 Aug 2013

Health care providers are missing opportunities to improve teens' vaccination coverage

Health care providers are missing opportunities to improve teens' vaccination coverage, reports a new study in the Journal of Adolescent Health.

2 Aug 2013

"Leukotriene B4" play opposing roles in turning inflammation on and off for allergic asthma, COPD

Bethesda, MD-Japanese researchers have made a new step toward understanding why-and how to stop-runaway inflammation for both chronic obstructive pulmonary disorder (COPD) and allergic asthma. In a new report appearing in the August 2013 issue of The FASEB Journal scientists show that two receptors of an inflammatory molecule, called "leukotriene B4," play opposing roles in turning inflammation on and off for allergic asthma and COPD.

2 Aug 2013

Visual images of skin cancer most effective in prompting skin self-examinations

Seeing pictures of skin cancer motivates people to regularly check their own moles, according to a new research paper from the School of Public Health and Health Systems at the University of Waterloo.

2 Aug 2013

Researchers hope to exploit unique metabolic profile of cancer

Researchers from the University of Illinois at Chicago College of Medicine have identified a characteristic unique to cancer cells in an animal model of cancer -- and they believe it could be exploited as a target to develop new treatment strategies.

2 Aug 2013

BMC, BUSM and JIPMER to jointly research on tuberculosis

Boston Medical Center and Boston University School of Medicine are partnering with the Jawaharlal Institute of Postgraduate Medical Education and Research to study tuberculosis. This research is supported by a five-year, $2.5 million grant from the Indo-U.S. Vaccine Action Program.

2 Aug 2013

Deletion of a protein improves ability to fight bacteria in mice with CGD

Deletion of a protein in white blood cells improves their ability to fight the bacteria staphylococcus aureus and possibly other infections in mice with chronic granulomatous disease (CGD), according to a National Institutes of Health study. CGD, a genetic disorder also found in people, is marked by recurrent, life-threatening infections. The study's findings appear online in The Journal of Clinical Investigation.

2 Aug 2013

New type of chemical modification affects proteins, could provide insights into causes of cancer

Scientists at The Scripps Research Institute (TSRI) have discovered a new type of chemical modification that affects numerous proteins within mammalian cells. The modification appears to work as a regulator of important cellular processes including the metabolism of glucose.

2 Aug 2013

Researchers identify new culprit that likely plays big role in severity of asthma

MD-A new culprit has been identified that likely plays a big role in the severity of asthma-a small protein chemokine called CCL26. These findings were published in the Journal of Leukocyte Biology and represent the first demonstration that CCL26 is a potent regulator of the migration of asthmatic eosinophils, commonly observed in asthmatic airways. Results from this discovery may lead to new drug targets for the treatment of asthma.

2 Aug 2013

Neuroscientists identify protein that contributes to cognitive deficits in AS

A team of neuroscientists has identified a protein in laboratory mice linked to impairments similar to those afflicted with Angelman syndrome (AS)—a condition associated with symptoms that include autism, intellectual disability, and motor abnormalities.

2 Aug 2013

Study: Ultrasound treatments may prevent acute kidney injury

Ultrasound treatments may prevent acute kidney injury that commonly arises after major surgery, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). The findings suggest that this simple and noninvasive therapy may be an effective precaution for patients at risk.

2 Aug 2013

Study: New therapeutic approach to treat prostate cancer

A study in the Journal of Biological Chemistry identifies a new therapeutic approach to treat prostate cancer. Conducted at Cincinnati Children's Hospital Medical Center, the research shows that expression of the FoxM1 protein is essential for prostate cancer to develop in mouse models. The study appears in the journal's Aug. 2 edition.

2 Aug 2013

Research aims to provide physicians a more targeted approach to treating ER+ breast cancer

The most commonly diagnosed form of breast cancer, termed estrogen receptor positive or ER+, accounts for the largest percentage of breast cancer deaths each year. Research by scientists at the HudsonAlpha Institute for Biotechnology and the University of Alabama at Birmingham Comprehensive Cancer Center aims to provide physicians a more targeted approach to treating ER+ breast cancer.

2 Aug 2013

Scientists use fMRI and EEG to unlock one of the human brain's mysteries

Physicists and neuroscientists from The University of Nottingham and University of Birmingham have unlocked one of the mysteries of the human brain, thanks to new research using functional Magnetic Resonance Imaging (fMRI) and electroencephalography (EEG).

2 Aug 2013

Medical Research News

Study reveals epigenetic mechanisms contribute to chronic disease susceptibility prior to birth

Trace substance in sugar improves muscle regeneration in mouse model with muscular dystrophy

Study finds that tens of billions of dollars spent each year for moderate chronic kidney disease

Research opens potential new avenue for cancer treatment

Researchers show that JQ1 drug can block molecular pathway responsible for heart failure

Omega-3 fatty acids can be used for treatment, prevention of skin and oral cancers: Research

UCLA researchers develop treatment approach for breast cancer metastasized to brain

Health care providers are missing opportunities to improve teens' vaccination coverage

"Leukotriene B4" play opposing roles in turning inflammation on and off for allergic asthma, COPD

Visual images of skin cancer most effective in prompting skin self-examinations

Researchers hope to exploit unique metabolic profile of cancer

BMC, BUSM and JIPMER to jointly research on tuberculosis

Deletion of a protein improves ability to fight bacteria in mice with CGD

New type of chemical modification affects proteins, could provide insights into causes of cancer

Researchers identify new culprit that likely plays big role in severity of asthma

Neuroscientists identify protein that contributes to cognitive deficits in AS

Study: Ultrasound treatments may prevent acute kidney injury

Study: New therapeutic approach to treat prostate cancer

Research aims to provide physicians a more targeted approach to treating ER+ breast cancer

Scientists use fMRI and EEG to unlock one of the human brain's mysteries

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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