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Clarified role of signal-relay proteins may help explain spread of cancer

Cell biologists at The Johns Hopkins University have teased apart two integral components of the machinery that causes cells to move. Their discovery shows that cellular projections, which act as hands to help a cell "crawl," are apparently always initiated by a network of message-relaying proteins inside the cell.

21 Oct 2013

Researchers identify key therapeutic target for cancers driven by KRAS protein

Patients with cancers driven by the protein KRAS, which are particularly hard to treat, may benefit from small molecules that attach to and disrupt the function of a KRAS-containing protein complex, according to results presented here at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, held Oct. 19-23.

20 Oct 2013

Research Institute receives Fast Track status for its gene therapy product for treatment of SMA

AveXis and BioLife, synthetic biology platform companies, today announced that The Research Institute at Nationwide Children's Hospital received Fast Track designation from the U.S. Food and Drug Administration for its scAAV9.CB.SMN gene therapy product for the treatment of spinal muscular atrophy (SMA).

19 Oct 2013

Study: Pds5 proteins modulate behavior of cohesins to ensure proper division of cells

Cohesins are protein complexes that join the two copies of each chromosome-called sister chromatids-to ensure that they are shared fairly between the daughter cells during cell division. In this way, each daughter cell receives exactly the same genetic information from the parent cell.

19 Oct 2013

Five Research Units established to uncover physiological basis for cognitive processes, cultural techniques

The Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) is establishing five new Research Units. This was decided by the DFG Senate at its October meeting. The purpose of the research collaborations is to offer researchers the possibility to pursue current, pressing issues in their subject areas and to establish innovative work directions.

19 Oct 2013

Dentist offers advanced teeth whitening options

Los Angeles tooth whitening dentist, Dr. Kevin Sands, offers advanced teeth whitening options to help patients erase many years' worth of stains from even the most discolored teeth.

19 Oct 2013

New book presents latest findings on reconstructive surgery of microtia/atresia of EAC

Remarkable progress in the development of new concepts and techniques used in reconstructive surgery of microtia/atresia of the external auditory canal (EAC) has been made since the beginning of the 21st century.

19 Oct 2013

RNA-based gene expression test potentially determine presence or absence of BRAF V600E mutation

Veracyte, Inc., a molecular diagnostics company pioneering the field of molecular cytology, today announced preliminary study results suggesting the potential for an RNA-based gene expression test to accurately detect the BRAF V600E gene mutation in thyroid nodule fine needle aspiration (FNA) samples.

19 Oct 2013

Thomson Reuters adds Cortellis Clinical Trials Intelligence for drug discovery and development

The Intellectual Property & Science business of Thomson Reuters, the world's leading provider of intelligent information for businesses and professionals, today announced the addition of Clinical Trials Intelligence to the Thomson Reuters CortellisTM suite, the industry's most comprehensive information solution for drug discovery and development.

19 Oct 2013

Wnt5A signaling pathway helps researchers determine who may respond to BRAF inhibitors

One of the challenges of understanding cancer is trying to determine the mechanisms that drive metastasis, or the process by which tumor cells are able to spread throughout the body.

19 Oct 2013

New prognostic tool forecasts survival of patients with advanced prostate cancer

For men with advanced prostate cancer that has progressed after taking hormones and undergoing chemotherapy, getting an accurate prognosis is critical to determine the next steps for treatment.

19 Oct 2013

Research: Hypermutation in cancer is more frequent in inactive X chromosome

Every case of cancer originates from changes in a person's genetic material (mutations). These usually occur as "somatic mutations" in individual cells during an individual's lifetime, rather than being inherited from a person's parents.

19 Oct 2013

Sugary drink consumption among young children spikes 8% in California

While consumption of soda and other sugary drinks among young children in California is starting to decline, a new study released today shows an alarming 8 percent spike among adolescents, the biggest consumers of these beverages.

19 Oct 2013

Study shows significant link between low dietary fiber intake and cardiometabolic risks

A new study published in the December issue of The American Journal of Medicine shows a significant association between low dietary fiber intake and cardiometabolic risks including metabolic syndrome, cardiovascular inflammation, and obesity.

19 Oct 2013

Boston Medical Center receives 2 research awards from PCORI to study delivery of cancer care

Boston Medical Center (BMC) has been approved to receive two research awards from the Patient-Centered Outcomes Research Institute (PCORI). One will study the delivery of cancer care to patients who face socio-legal barriers and the other will test the effectiveness of integrative medical group visits (IMGV) for treating chronic pain.

19 Oct 2013

Oral nutritional supplements linked with decreased probability of 30-day hospital readmission

In the U.S., one in five Medicare patients is readmitted to a hospital each year at an estimated cost of $17.5 billion annually.i To reduce this impact, the Affordable Care Act (ACA) has introduced hospital penalties based on readmissions conditions that commonly affect patients aged 65 and older - including acute myocardial infarction, congestive heart failure and pneumonia.

19 Oct 2013

Medical Research News

Clarified role of signal-relay proteins may help explain spread of cancer

Researchers identify key therapeutic target for cancers driven by KRAS protein

Research Institute receives Fast Track status for its gene therapy product for treatment of SMA

Study: Pds5 proteins modulate behavior of cohesins to ensure proper division of cells

Five Research Units established to uncover physiological basis for cognitive processes, cultural techniques

Dentist offers advanced teeth whitening options

New book presents latest findings on reconstructive surgery of microtia/atresia of EAC

RNA-based gene expression test potentially determine presence or absence of BRAF V600E mutation

Thomson Reuters adds Cortellis Clinical Trials Intelligence for drug discovery and development

Wnt5A signaling pathway helps researchers determine who may respond to BRAF inhibitors

New prognostic tool forecasts survival of patients with advanced prostate cancer

Research: Hypermutation in cancer is more frequent in inactive X chromosome

Sugary drink consumption among young children spikes 8% in California

Study shows significant link between low dietary fiber intake and cardiometabolic risks

Boston Medical Center receives 2 research awards from PCORI to study delivery of cancer care

Oral nutritional supplements linked with decreased probability of 30-day hospital readmission

Cavity restoration predicts dental bleeding, calculus

Recombinant hormone could REPLACE calcium supplements

FEV1 poor mortality predictor in elderly

Schizophrenic hippocampal abnormalities blamed on glutamate

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

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