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Keeping Alzheimer's disease in check

The future is looking good for drugs designed to combat Alzheimer's disease. EPFL scientists have unveiled how two classes of drug compounds currently in clinical trials work to fight the disease. Their research suggests that these compounds target the disease-causing peptides with high precision and with minimal side-effects.

2 Aug 2013

ASH to award 2013 William Dameshek Prize to Andrew S. Weyrich

The American Society of Hematology will present the 2013 William Dameshek Prize to Andrew S. Weyrich, PhD, of The University of Utah for his seminal research on the cellular and molecular causes of blood clots.

2 Aug 2013

Almost 50% percent of population suffers from tooth sensitivity

Almost 50% percent of the population suffers from tooth sensitivity to cold, sweet and hot foods and liquids, according to a nationwide survey of 1,056 adults age 18—65+. Almost half of respondents had tried sensitivity toothpastes, but only about one-third of those found their experience to be positive, noted Larry Fishman, president of Majestic Drug Co., Inc.

2 Aug 2013

Researchers identify precise method for determining bone marrow involvement in DLBCL patients

A more precise method for determining bone marrow involvement in patients with diffuse large B-cell lymphoma-a key factor in tailoring patient management plans-has been identified by researchers in a study published in the August issue of The Journal of Nuclear Medicine.

2 Aug 2013

NanoString announces Early Access Program for nCounter Elements used in translational research

NanoString Technologies, Inc. (NASDAQ: NSTG), a provider of life science tools for translational research and molecular diagnostic products, today announced an Early Access Program for nCounter Elements™, a line of General Purpose Reagents (GPRs) developed specifically to meet the needs of translational research and clinical laboratories.

From NanoString Technologies 2 Aug 2013

Build-up of harmful chemicals in the body affects people of all social standings

A new study published this week has found that the build-up of harmful chemicals in the body is affecting people of all social standings -- not just those from economically deprived backgrounds as previously thought.

2 Aug 2013

Protein linked to learning induces cocaine addiction, say researchers

A team of researchers says it has solved the longstanding puzzle of why a key protein linked to learning is also needed to become addicted to cocaine. Results of the study, published in the Aug. 1 issue of the journal Cell, describe how the learning-related protein works with other proteins to forge new pathways in the brain in response to a drug-induced rush of the “pleasure” molecule dopamine.

2 Aug 2013

Wild type genetic background affects outcomes of interactions between genetic mutations

In the current issue of PLOS Genetics, Michigan State University genetic scientists have begun to understand how the rest of the genome interacts with such mutations to cause the differences we see among individuals.

2 Aug 2013

Researchers now have more complete picture of mTORC1 pathway that can lead to cancer, diabetes

Deciphering the body's complex molecular pathways that lead to disease when they malfunction is highly challenging. Researchers at Sanford-Burnham Medical Research Institute now have a more complete picture of one particular pathway that can lead to cancer and diabetes. In the study published by Molecular Cell, the scientists uncovered how a protein called p62 has a cascade affect in regulating cell growth in response to the presence of nutrients such as amino acids and glucose. Disrupting this chain may offer a new approach to treating disease.

2 Aug 2013

Research: Larger lungs are associated with increased chance of survival

Transplant teams have long tried to match the size of donor lungs to the size of the recipient as closely as possible, concerned that lungs of the wrong size could lead to poor lung function and poor outcomes.

2 Aug 2013

Clinicians should be aware of use of herbal supplements while breastfeeding

In an article published in this month's issue of Pediatrics In Review, researchers from Boston University School of Medicine (BUSM) stress the importance of physicians recognizing that many mothers use herbal supplements while breastfeeding in order to make accurate health assessments for both mother and child.

2 Aug 2013

Duke Medicine researchers identify a protein critical to TMJD pain

Temporomandibular joint disorder (TMJD) is the most common form of oral or facial pain, affecting over 10 million Americans. The chronic disorder can cause severe pain often associated with chewing or biting down, and lacks effective treatments.

2 Aug 2013

New finding suggests potential to improve safety, performance of reprogrammed cells

The enormous promise of regenerative medicine is matched by equally enormous challenges. But a new finding by a team of researchers led by Weill Cornell Medical College has the potential to improve both the safety and performance of reprogrammed cells.

2 Aug 2013

Study offers new hope for treatment of diffuse large B-cell lymphoma

Researchers have discovered how an experimental drug is capable of completely eradicating human lymphoma in mice after just five doses. The study, led by researchers at Weill Cornell Medical College, sets the stage for testing the drug in clinical trials of diffuse large B-cell lymphoma, the most common subtype of non-Hodgkin lymphoma, itself the seventh most frequently diagnosed cancer in the U.S.

2 Aug 2013

Cancer biomarker tests undervalued by doctors and patients, authors say

There's a major roadblock to creating personalized cancer care. Doctors need a way to target treatments to patients most likely to benefit and avoid treating those who will not. Tumor biomarker tests can help do this.

2 Aug 2013

Study shows blocking dietary sugar in tumor cells may reduce cancer risk and progression

Blocking dietary sugar and its activity in tumor cells may reduce cancer risk and progression, according to researchers from the Icahn School of Medicine. The study, conducted in fruit flies and published in the journal Cell, provides insight as to why metabolism-related diseases such as diabetes or obesity are associated with certain types of cancer, including pancreatic, breast, liver, and colon cancers

2 Aug 2013

Researchers reveal location of human blood stem cells that may improve bone marrow transplants

McMaster University researchers have revealed the location of human blood stem cells that may improve bone marrow transplants. The best stem cells are at the ends of the bone.

2 Aug 2013

Scientists prevent cell sleep to reduce chance of tumor recurrence

An international research team led by University of Pittsburgh Cancer Institute (UPCI) scientists discovered that by preventing cancer cells from entering a state of cellular sleep, cancer drugs are more effective, and there is a lower chance of cancer recurrence.

2 Aug 2013

Understanding how brain networks function

A boost in the speed of brain scans is unveiling new insights into how brain regions work with each other in cooperative groups called networks.

2 Aug 2013

Researchers find a crucial on-off switch in visual development

A discovery by a University of Maryland-led research team offers hope for treating "lazy eye" and other serious visual problems that are usually permanent unless they are corrected in early childhood.

2 Aug 2013

Medical Research News

Keeping Alzheimer's disease in check

ASH to award 2013 William Dameshek Prize to Andrew S. Weyrich

Almost 50% percent of population suffers from tooth sensitivity

Researchers identify precise method for determining bone marrow involvement in DLBCL patients

NanoString announces Early Access Program for nCounter Elements used in translational research

Build-up of harmful chemicals in the body affects people of all social standings

Protein linked to learning induces cocaine addiction, say researchers

Wild type genetic background affects outcomes of interactions between genetic mutations

Researchers now have more complete picture of mTORC1 pathway that can lead to cancer, diabetes

Research: Larger lungs are associated with increased chance of survival

Clinicians should be aware of use of herbal supplements while breastfeeding

Duke Medicine researchers identify a protein critical to TMJD pain

New finding suggests potential to improve safety, performance of reprogrammed cells

Study offers new hope for treatment of diffuse large B-cell lymphoma

Cancer biomarker tests undervalued by doctors and patients, authors say

Study shows blocking dietary sugar in tumor cells may reduce cancer risk and progression

Researchers reveal location of human blood stem cells that may improve bone marrow transplants

Scientists prevent cell sleep to reduce chance of tumor recurrence

Understanding how brain networks function

Researchers find a crucial on-off switch in visual development

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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