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Combination of NGF microspheres and chitosan conduits exhibit better effects in repairing facial nerve injury

The chitosan molecule can promote nerve cell adherence and growth along the surface of the material. It can enhance the adherence and influx of Schwann cells, thus encouraging the growth of axons.

28 Dec 2013

Protein responsible for excretion of copper in body cells utilizes unique transport mechanism

We are fundamentally dependent on the presence of copper in the cells of the body. Copper is actually part of the body's energy conversion and protective mechanisms against oxygen radicals, as well as part of the immune system, and it also has great importance for the formation of e.g. hormones and neurotransmitters.

28 Dec 2013

PCORI awards $93.5M to patient-powered research networks to boost efficiency of health research

A network of children's hospitals, data partners, and specialty networks led by The Children's Hospital of Philadelphia was recently approved for an award from the Patient-Centered Outcomes Research Institute (PCORI) to develop and expand its work as part of PCORnet: the National Patient-Centered National Clinical Research Network.

28 Dec 2013

Study explores the possibility that smoking behaviors account for highest mortality

Between 1965 and 2004, the distribution of states with the highest mortality changed dramatically. In 1965, the states with the highest mortality (Rhode Island, Alaska, Delaware, Pennsylvania, and New Hampshire) were spread across geographic regions.

28 Dec 2013

Rho-associated protein kinase regulates hippocampal neurite growth, microtubule formation

Rho-associated protein kinase is an essential regulator of cytoskeletal dynamics during the process of neurite extension. However, whether Rho kinase regulates microtubule remodeling or the distribution of adhesive proteins to mediate neurite outgrowth remains unclear.

28 Dec 2013

Consumption of nuts promotes health and longevity, finds study

In a study published November 20, 2013 in the New England Journal of Medicine1, researchers looked at the association of nut consumption with total and cause-specific mortality among 76,464 women in the Nurses' Health Study and 42,498 men in the Health Professionals Follow-up Study. Consumption of nuts, including tree nuts (such as pistachios, almonds, Brazil nuts, cashews, hazelnuts, macadamias, pecans, pine nuts, and walnuts), was inversely associated with total mortality in both men and women, independent of other predictors for death.

28 Dec 2013

Study shows beneficial effects of normobaric oxygen on cerebral ischemic injury

Normobaric oxygen has the rapid and non-invasive characteristics and may have therapeutic effects on ischemic/hypoxic disease.

28 Dec 2013

Perinatal probiotic supplements do not prevent childhood asthma

There is insufficient evidence to support the use of probiotic supplements during pregnancy or infancy to prevent the development of asthma in infants, Canadian researchers report.

27 Dec 2013

CotH protein mediates fungal invasion of host cells during mucormycosis

Opportunistic infection of individuals on immunosuppressive therapy are a major problem for patient outcome, despite current prophylactic strategies.

27 Dec 2013

Nonsteroidal anti-inflammatory agent delays neuropathy progression, preserves quality of life

Among patients with familial amyloid polyneuropathy, a lethal, genetic neurodegenerative disease, use of the nonsteroidal anti-inflammatory agent diflunisal compared with placebo for 2 years reduced the rate of progression in neurological impairment and preserved quality of life, according to a study appearing in the December 25 issue of JAMA.

27 Dec 2013

FIDELITY project compares surgical treatment of degenerative meniscal tears to placebo surgery

The Finnish Degenerative Meniscal Lesion Study (FIDELITY) compared surgical treatment of degenerative meniscal tears to placebo surgery.

27 Dec 2013

Researchers explore ways to overcome transplant rejection

Given that 10.5 % of patients who receive a transplant reject the new organ, researchers at the Center of Research and Advanced Studies of the National Polytechnic Institute (Cinvestav) are working in the design of a tool capable of preventing this problem.

27 Dec 2013

Researchers study health consequences of RTE proliferation that occurs in aging tissues

The genomes of organisms from humans to corn are replete with "parasitic" strands of DNA that, when not suppressed, copy themselves and spread throughout the genome, potentially affecting health. Earlier this year Brown University researchers found that these "retrotransposable elements" were increasingly able to break free of the genome's control in cultures of human cells.

27 Dec 2013

Streptococcus biofilms persist on objects, surfaces in daycare center for longer periods after cleaning

Numerous scientific studies have concluded that two common bacteria that cause colds, ear infections, strep throat and more serious infections cannot live for long outside the human body.

27 Dec 2013

Scientists analyze nutrition and physical activity behavior that could prevent risk of diabetes

"I'm going to do more sport in the new year." Hardly any resolution is made more frequently than this one after the calorie-filled Christmas holidays - and hardly one that is broken as frequently. A team headed by Prof. Wolfgang Schlicht from the Institute for Sport and Movement Science at the University of Stuttgart are investigating behaviour techniques in the framework of the project "PREVIEW" with which the physical activity behaviour can be changed in the long term. T

27 Dec 2013

Cells' adaptations to low oxygen conditions inside tumors promote breast cancer's spread

Biologists at The Johns Hopkins University have discovered that low oxygen conditions, which often persist inside tumors, are sufficient to initiate a molecular chain of events that transforms breast cancer cells from being rigid and stationery to mobile and invasive.

27 Dec 2013

Oral ingestion of inosine compound raises urate levels, shows Parkinson's study

New findings published in JAMA Neurology from research into a potentially protective therapy for Parkinson's disease (PD) show that with medical supervision, urate levels may safely be raised while mitigating risk of complications such as gout.

27 Dec 2013

Researchers develop a class of compounds that may help eradicate Chagas disease

A team of researchers from Canada has developed a class of compounds which may help eradicate a neglected tropical disease that is currently hard to kill in its chronic form. The research was published ahead of print in Antimicrobial Agents and Chemotherapy.

27 Dec 2013

Research: Neuropeptides may serve as index for evaluating early peripheral nerve injury

Substance P and calcitonin gene-related peptide are the main neuropeptides in peripheral nerve ganglia, which can anterogradely transmit nociceptive information to the central nervous system.

27 Dec 2013

Stem cell-based gene therapy shows long-term outcomes for treatment of genetic skin diseases

Stem cell-based gene therapy holds promise for the treatment of devastating genetic skin diseases, but the long-term clinical outcomes of this approach have been unclear.

27 Dec 2013

Medical Research News

Combination of NGF microspheres and chitosan conduits exhibit better effects in repairing facial nerve injury

Protein responsible for excretion of copper in body cells utilizes unique transport mechanism

PCORI awards $93.5M to patient-powered research networks to boost efficiency of health research

Study explores the possibility that smoking behaviors account for highest mortality

Rho-associated protein kinase regulates hippocampal neurite growth, microtubule formation

Consumption of nuts promotes health and longevity, finds study

Study shows beneficial effects of normobaric oxygen on cerebral ischemic injury

Perinatal probiotic supplements do not prevent childhood asthma

CotH protein mediates fungal invasion of host cells during mucormycosis

Nonsteroidal anti-inflammatory agent delays neuropathy progression, preserves quality of life

FIDELITY project compares surgical treatment of degenerative meniscal tears to placebo surgery

Researchers explore ways to overcome transplant rejection

Researchers study health consequences of RTE proliferation that occurs in aging tissues

Streptococcus biofilms persist on objects, surfaces in daycare center for longer periods after cleaning

Scientists analyze nutrition and physical activity behavior that could prevent risk of diabetes

Cells' adaptations to low oxygen conditions inside tumors promote breast cancer's spread

Oral ingestion of inosine compound raises urate levels, shows Parkinson's study

Researchers develop a class of compounds that may help eradicate Chagas disease

Research: Neuropeptides may serve as index for evaluating early peripheral nerve injury

Stem cell-based gene therapy shows long-term outcomes for treatment of genetic skin diseases

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