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Merrion, Novo Nordisk enter Collaboration and Option agreement for GIPET technology

Merrion Pharmaceuticals Plc, a publicly listed product development company, today announced the signing of a Collaboration and Option agreement with Novo Nordisk. The agreement will evaluate the ability of Merrion's patented GIPET® technology to boost the oral bioavailability of an undisclosed proprietary compound.

22 Dec 2010

Spinal Botox injection reduces pain

Botulinum neurotoxin type A (BoNT/A)—better known as Botox—reduces responses to an inflammation-related pain stimulus when injected into the spinal canal in mice, reports a study in the January issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

22 Dec 2010

Prenatal iron-folic acid supplementation increases intellectual, motor function in children

In developing countries where iron deficiency is prevalent, prenatal iron-folic acid supplementation increased offspring intellectual and motor functioning during school age, according to researchers from the Johns Hopkins Bloomberg School of Public Health.

22 Dec 2010

Men above age 75 with high-risk prostate cancer often under-treated

Older men with high-risk prostate cancer frequently are offered fewer - and less effective - choices of treatment than younger men, potentially resulting in earlier deaths, according to a new UCSF study.

22 Dec 2010

Altering balance among immune system cells could hold potential for T2D-associated inflammation treatment

Researchers from Boston University School of Medicine (BUSM) have demonstrated that certain T cells require input from monocytes in order to maintain their pro-inflammatory response in people with type 2 diabetes (T2D). The study also showed, for the first time, how a loss in homeostasis in this group of T cells most likely promotes chronic inflammation associated with T2D.

22 Dec 2010

Popular Science magazine honors ONR-funded researchers on 2010 'Brilliant 10' list

Dubbed the "Brilliant 10" by Popular Science, two researchers on the magazine's recently released 2010 list of top young scientists have received funding from the Office of Naval Research (ONR).

22 Dec 2010

Moderately and morbidly obese drivers face increase risk of death during severe vehicle crashes

Moderately and morbidly obese persons face many health issues -- heart disease, diabetes, hypertension, stroke, gallbladder disease and others. Now, increased chances of dying while driving during a severe auto accident can be added to the list.

22 Dec 2010

Smoking can increase pain severity in cancer patients

The relationship between smoking and cancer is well established. In a study published in the January 2011 issue of PAIN, researchers report evidence to suggest that cancer patients who continue to smoke despite their diagnosis experience greater pain than nonsmokers.

22 Dec 2010

Exercise and Vitamin D supplementation most effective in reducing fall among seniors

A systematic review of over 50 clinical trials finds that exercise and Vitamin D supplements are the best ways to reduce the risk of falling in people aged 65 and over. The review is published in the December 21 issue of Annals of Internal Medicine and was commissioned by the US Preventive Services Task Force.

22 Dec 2010

High LSC scores associated with adverse outcomes in AML patients

In an examination of leukemic stem cells (LSC), researchers have found that patients with acute myeloid leukemia who had higher activity of certain LSC genes had worse overall, event-free and relapse-free survival, according to a study in the December 22/29 issue of JAMA.

21 Dec 2010

New genetic alteration predisposes individuals to Cowden syndrome

Researchers have identified a new genetic alteration that predisposes individuals to Cowden syndrome, a rare disorder that is characterized by high risks of breast, thyroid and other cancers, according to preliminary research published in the December 22/29 issue of JAMA.

21 Dec 2010

Presence of CTCs may predict disease recurrence in patients with neck and head cancer

A new study suggests that the presence of tumor cells in the circulating blood of patients with squamous cell cancer of the head and neck may predict disease recurrence and reduced survival.

21 Dec 2010

Echinacea only offers modest benefit in common cold: study

In a large clinical trial involving more than 700 adults and children researchers showed that the popular herbal remedy Echinacea can cut only half a day from a week long common cold. Echinacea has been marketed for a long time for the common cold. Echinacea, also known as purple coneflower has been shown to have benefits in some earlier studies while some show no benefits.

21 Dec 2010

Working more closely with community will make research more meaningful, say Johns Hopkins faculty

A survey conducted by Johns Hopkins faculty found strong support among their peers for working more closely with the minority, inner-city community that surrounds the institution. Overall, 91 percent of faculty responders said closer ties make research more relevant to those it ultimately serves, and 87 percent said it improves the quality of research.

21 Dec 2010

Pro-Pharmaceuticals, Mount Sinai collaborate to evaluate anti-fibrotic effects of Galectin-targeting compounds

Pro-Pharmaceuticals, Inc., the leading developer of Galectin therapeutics to treat cancer and fibrosis, today announced it has entered into a new research collaboration with Mount Sinai School of Medicine to evaluate in pre-clinical models, the anti-fibrotic effects of several of the Company's novel, Galectin-targeting compounds.

21 Dec 2010

USC researchers analyse radon levels in Galicia secondary schools

Researchers from the University of Santiago de Compostela (USC) have analysed levels of radon, a natural radioactive gas, in 58 secondary schools in Galicia.

21 Dec 2010

Whites with mutations more likely to be susceptible to cocaine abuse

Nearly one in five whites could carry a genetic variant that substantially increases their odds of being susceptible to severe cocaine abuse, according to new research.

21 Dec 2010

Investigator to receive AGA-General Mills Bell Institute of Health and Nutrition Research Scholar Award

The American Gastroenterological Association Foundation for Digestive Health and Nutrition announced that Anisa Shaker, MD, is the recipient of the AGA-General Mills Bell Institute of Health and Nutrition Research Scholar Award in Gut Physiology and Health.

21 Dec 2010

Study provides evidence on prevalence of two separate mosquito species which carry malaria parasite

In notable back-to-back papers appearing in the prestigioous journal Science in October, teams of researchers, one led by Nora Besansky, a professor of biological sciences and a member of the Eck Institute for Global Health at the University of Notre Dame, provided evidence that Anopheles gambiae, which is one of the major mosquito carriers of the malaria parasite in Sub-Saharan Africa, is evolving into two separate species with different traits.

21 Dec 2010

Invitations open for fourth annual Young Investigator Grant for Probiotics Research

Today, the Global Probiotics Council (GPC), a committee formed by Danone and YAKULT HONSHA CO., LTD., announced the launch of the fourth annual Young Investigator Grant for Probiotics Research (YIGPRO). This grant provides two awards, each in the amount of $50,000, to rising young stars. This year's grant focus is on the role of probiotics and gastrointestinal microbiota in health and wellness. Applications will be accepted until February 15, 2011.

21 Dec 2010

Medical Research News

Merrion, Novo Nordisk enter Collaboration and Option agreement for GIPET technology

Spinal Botox injection reduces pain

Prenatal iron-folic acid supplementation increases intellectual, motor function in children

Men above age 75 with high-risk prostate cancer often under-treated

Altering balance among immune system cells could hold potential for T2D-associated inflammation treatment

Popular Science magazine honors ONR-funded researchers on 2010 'Brilliant 10' list

Moderately and morbidly obese drivers face increase risk of death during severe vehicle crashes

Smoking can increase pain severity in cancer patients

Exercise and Vitamin D supplementation most effective in reducing fall among seniors

High LSC scores associated with adverse outcomes in AML patients

New genetic alteration predisposes individuals to Cowden syndrome

Presence of CTCs may predict disease recurrence in patients with neck and head cancer

Echinacea only offers modest benefit in common cold: study

Working more closely with community will make research more meaningful, say Johns Hopkins faculty

Pro-Pharmaceuticals, Mount Sinai collaborate to evaluate anti-fibrotic effects of Galectin-targeting compounds

USC researchers analyse radon levels in Galicia secondary schools

Whites with mutations more likely to be susceptible to cocaine abuse

Investigator to receive AGA-General Mills Bell Institute of Health and Nutrition Research Scholar Award

Study provides evidence on prevalence of two separate mosquito species which carry malaria parasite

Invitations open for fourth annual Young Investigator Grant for Probiotics Research

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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