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Reducing calorie intake can restrict growth, spread of brain cancer: Researchers

Researchers at Boston College, MA, have found that reducing calorie intake can restrict the growth and spread of brain cancer. Writing in ASN NEURO, Laura Shelton and colleagues report success with mice suffering from glioblastoma multiforme, the most aggressive and invasive form of primary human brain cancer.

23 Jul 2010

Inequalities in premature mortality continue to rise in Britain: Study

The level of inequalities in premature mortality between different areas of Britain has almost surpassed those seen shortly before the economic crash of 1929 and the economic depression of the 1930s, according to a new study published on bmj.com today.

23 Jul 2010

Study focuses on health issues of PGDP workers

A five-year study into the causes of deaths of workers at Paducah Gaseous Diffusion Plant shows significantly lower death rates from all causes and cancer in general when compared to the overall United States population. This is known by occupational health researchers as the "healthy worker effect". However, death from lymphatic and bone marrow cancers such as leukemia or multiple myeloma were slightly above national rates.

23 Jul 2010

New biophotonic imaging method monitors transformations of cellular macromolecules during apoptosis in real-time

Apoptosis, programmed cell death, is essential to normal development, healthy immune system function, and cancer prevention. The process dramatically transforms cellular structures but the limitations of conventional microscopy methods have kept much about this structural reorganization a mystery.

23 Jul 2010

Young women more likely to die in hospitals following heart attacks: Study

A new study by researchers at UMDNJ-Robert Wood Johnson Medical School has found that women between the ages of 35 and 54 were more likely to die in hospitals following heart attacks than men of a similar age. This finding from a sample of more than 423,000 patients can be seen as surprising, given that women, on average, develop their first acute myocardial infarction -- or heart attack -- about 10 years later than men, and are overall less likely to develop myocardial infarction than are men.

23 Jul 2010

Circulating aberrant cells increase as non-small cell lung cancer progresses

A novel approach detects genetically abnormal cells in the blood of non-small cell lung cancer patients that match abnormalities found in tumor cells and increase in number with the severity of the disease, a research team led by scientists at The University of Texas MD Anderson Cancer Center report in the journal Clinical Cancer Research.

23 Jul 2010

More time spent sitting linked to higher risk of death

Childhood physical abuse associated with adulthood heart disease

Childhood physical abuse is associated with significantly elevated rates of heart disease in adulthood, according to new findings by University of Toronto researchers, published in this month's issue of the journal Child Abuse & Neglect.

23 Jul 2010

IBS associated with structural changes in specific brain regions

A large academic study has demonstrated structural changes in specific brain regions in female patients with irritable bowel syndrome, a condition that causes pain and discomfort in the abdomen, along with diarrhea, constipation or both

23 Jul 2010

African Americans at increased risk of kidney failure caused by hypertension

Regardless of demographics, African American patients with hypertensive nephrosclerosis have a higher rate of developing end stage renal disease than dying prematurely, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology.Earlier studies showed patients of all races with Chronic Kidney Disease were at greater risk of dying prematurely from cardiovascular disease than reaching ESRD.

23 Jul 2010

New technique to detect abnormal cell circulation in non-small lung cancer

Researchers at The University of Texas M. D. Anderson Cancer Center are testing a new technique for identifying circulating genetically abnormal cells, which can lead to poor prognosis, in patients with non-small cell lung cancer.

23 Jul 2010

NVHR releases statement on New York Times article 'Hope against Hepatitis C'

In response to today's New York Times article, "Hope against Hepatitis C," Andrew Muir, M.D., M.H.S., Director, Gastroenterology/Hepatology Research, Duke Clinical Research Institute and Steering Committee Member of the National Viral Hepatitis Roundtable (NVHR) released the following statement:

23 Jul 2010

Effective prevention therapy, early critical care and rehabilitation needed to overcome cost burden of stroke

The consequences of stroke, reported to be the third leading cause of death in the U.S., can extend beyond the physical to impose devastating financial burdens on families and society in general. According to the American Heart Association, the total direct and indirect costs of stroke in 2008 have been estimated at $65.5 billion.

23 Jul 2010

Low-calorie sweeteners reduce caloric intake, weight

A new study published in the August 2010 journal, Appetite, further demonstrates that people who consume low-calorie sweeteners are able to significantly reduce their caloric intake and do not overeat.In fact, study participants who received the sugar substitutes instead of sugar consumed significantly fewer calories and there was no difference in hunger levels despite having fewer calories overall.

23 Jul 2010

Repetition of DRD4 genotype may increase risk for extensive alcohol use

Your friend walks into a bar to meet you for happy hour. He sidles up to the bar and orders a drink - does that make you more likely to get a drink yourself? According to new findings reported in Psychological Science, a journal of the Association for Psychological Science, genetics may determine the extent to which you are influenced by social drinking cues - signals such as advertisements, drinks placed on a bar, and seeing other people around you drinking.

23 Jul 2010

Study on role of nucleolinus in cell cycle regulation

When searching for long-lost treasure, sometimes all you need is a good flashlight.Such a "flashlight," developed at the Marine Biological Laboratory's Josephine Bay Paul Center, has been used to illuminate a long-neglected cellular component - the nucleolinus - and confirm its role in cell division.

23 Jul 2010

National Jewish Health receives $31M NIH contract to study skin infections associated with atopic dermatitis

The National Institute of Allergy and Infections Disease has awarded a five-year $31 million contract to National Jewish Health, which is leading a consortium of academic medical centers seeking to better understand skin infections associated with atopic dermatitis. The researchers will focus on antibiotic-resistant staphylococcus aureus (MRSA) infections and widespread viral infections of the skin, both of which are more prevalent among atopic dermatitis patients.

23 Jul 2010

Lack of SIRT1 protein exhibits impaired memory and learning: Study

A protein implicated in many biological processes also may play a role in memory, according to a study led by the University of Southern California and the National Institute on Aging at the National Institutes of Health.The findings, published this week in the Journal of Neuroscience, agree with research by a different team published online by Nature on July 11. Both studies found that mice lacking the protein SIRT1 exhibited impaired memory and learning, suggesting SIRT1's importance to those functions.

23 Jul 2010

Nestle announces collaborative study with Cleveland Clinic Lerner Research Institute on diet rich in whole grains

Nestle USA Chairman and CEO Brad Alford has announced that Nestle Research Center, based in Lausanne, Switzerland, has donated US $500,000 to Cleveland Clinic's Lerner Research Institute. The gift will fund a collaborative study focused on examining the effects of a diet rich in whole grains on body composition and energy metabolism.

23 Jul 2010

Researchers discover fundamental entry mechanism of fungal microbes into plant and human host cells

A research team led by scientists at the Virginia Bioinformatics Institute (VBI) at Virginia Tech has discovered a fundamental entry mechanism that allows dangerous fungal microbes to infect plants and cause disease. The discovery paves the way for the development of new intervention strategies to protect plant, and even some animal cells, from deadly fungal infections. The findings are published in the July 23 edition of the journal Cell.

23 Jul 2010