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ER stress response is major driver of insulin resistance, say researchers

Biologists have long known that an enzyme called the PI 3-kinase is a crucial actor in the main molecular pathway for insulin signaling in cells. Researchers at Joslin Diabetes Center now have uncovered startling evidence that one of the proteins in this enzyme also drives a pathway with an opposite result-triggering a stress response that leads to insulin resistance.

29 Mar 2010

TB-causing bacteria can hijack fat metabolism to drive progression of the disease

The factors instrumental in triggering latent tuberculosis infection to progress into active disease have long remained elusive to researchers. New insight into the mystery is provided by Professor David Russell, speaking at the Society for General Microbiology's spring meeting in Edinburgh today. His work could help develop innovative strategies for treating the disease.

29 Mar 2010

New approach may circumvent lost response in insulin due to obesity

Researchers at Children's Hospital Boston have identified a new strategy for treating type 2 diabetes, identifying a cellular pathway that fails when people become obese. By activating this pathway artificially, they were able to normalize blood glucose levels in severely obese and diabetic mice. Their findings will be published online by Nature Medicine on March 28.

29 Mar 2010

UCSF approach may one day be used to create new periods of plasticity in human brain

UCSF scientists report that they were able to prompt a new period of "plasticity," or capacity for change, in the neural circuitry of the visual cortex of juvenile mice. The approach, they say, might some day be used to create new periods of plasticity in the human brain that would allow for the repair of neural circuits following injury or disease.

27 Mar 2010

SAMHSA survey: Underage drinking rates reach more than 27.6% in the past month

More than a quarter of youth aged 12-20 (27.6 percent) drank alcohol in the past month, according to a survey by the Substance Abuse and Mental Health Services Administration. The study shows that the underage drinking rates were as high as 40 percent in some states such as North Dakota and Vermont.

27 Mar 2010

New scientific discoveries show that Canadian maple syrup can be good for health

The Federation of Quebec Maple Syrup Producers is pleased to report on two new scientific discoveries which show that Canadian maple syrup can be good for you. These studies build on recent findings on the nutritional value of maple products, which have revealed both the antioxidant properties of maple syrup as well as the discovery of substantial quantities of abscisic acid.

27 Mar 2010

Study: Automatic reporting of estimated GFR may result in unnecessary referrals by physicians

With a concern that the automatic reporting of estimated glomerular filtration rate (the flow rate of filtered fluid through the kidney, which is used to define the stage and severity of chronic kidney disease) may result in unnecessary referrals by physicians, new research indicates that automated laboratory reporting was associated with a significant increase in first-time visits to a kidney specialist, particularly among those at increased risk of late detection of kidney disease (such as older or female patients), according to a study in the March 24/31 issue of JAMA.

27 Mar 2010

Early stopping of clinical trials result in misleading estimates of treatment effects: Study

An international study of nearly 100 clinical trials that were stopped early due to positive treatment effects has found that many of those effects were exaggerated. The authors of the study — published in the current issue of the Journal of the American Medical Association — recommend that researchers resist pressures to end clinical trials early and continue trials for longer periods before even considering premature termination.

27 Mar 2010

Young adults increasingly flocking to EDs for medical treatment

Young adults, a generally healthy population, are increasingly flocking to emergency departments instead of outpatient clinics for medical treatment. Young adults remain the most likely age group to lack health insurance and often lose their insurance during this pivotal transition period between adolescence and adulthood.

27 Mar 2010

Study finds association between socioeconomic position and risk of death

An analysis of nearly 25 years of data for about 10,000 civil servants in London finds an association between socioeconomic position and risk of death, with much of this relation accounted for by health behaviors such as smoking, alcohol consumption, diet and physical activity, according to a study in the March 24/31 issue of JAMA.

27 Mar 2010

Thermo Fisher Scientific, Eli Lilly expand clinical trial materials supply chain relationship

Thermo Fisher Scientific Inc., the world leader in serving science, and biopharmaceutical company Eli Lilly and Company, announced today that they have expanded their clinical trial materials supply chain relationship. As part of a new five-year agreement, the Fisher Clinical Services business of Thermo Fisher will take over responsibility for Lilly’s in-house clinical trial materials manufacturing, packaging and labeling operations on-site at the Lilly Technology Center – North in Indianapolis. This transition is expected to be completed in the summer of 2010.

From Thermo Fisher Scientific Inc. 27 Mar 2010

Ontario announces increase in budget for research and innovation, OBIO applauds

Urgently needed capital should become more accessible to Ontario’s bioscience companies and help create jobs in the biotechnology sector, thanks to Ontario’s 2010 budget. An announced increase in the budget of the Ministry of Research and Innovation coupled with anticipated adjustments to existing funding programs designed to encourage research and innovation are applauded by Ontario Bioscience Industry Organization (OBIO).

27 Mar 2010

Depressed Latinos who stigmatize mental illness less likely to take medication: Study

A new, small study of low-income, depressed Latinos finds that those who stigmatize mental illness are less likely than others are to take medication, keep scheduled appointments and control their condition.

27 Mar 2010

Studies shed light on treatment options for women carrying BRCA1 and BRCA2 genetic mutations

Two studies to be presented at the seventh European Breast Cancer Conference (EBCC7) in Barcelona today (Friday) and tomorrow (Saturday), shed light on the treatment options facing women carrying the BRCA1 and BRCA2 genetic mutations which predispose them to breast cancer.

27 Mar 2010

ETSU wins $9.1M federal stimulus grant from NIH

East Tennessee State University has won a $9.1 million federal stimulus grant from the National Institutes of Health. It is the largest federal grant ever awarded to the university's James H. Quillen College of Medicine.

27 Mar 2010

Ford Motor donates $255,000 to fund completion of Oakwood Healthcare System's research study

Ford Motor Company announced today it is donating an additional $255,000 to fund the completion of a pioneering multi-year Oakwood Healthcare System research study into the prevention of heart disease – a leading cause of death among American women.

27 Mar 2010

New study may give men a way to combat high cholesterol without drugs

A new study from Iowa State University's Nutrition and Wellness Research Center may give men a way to combat high cholesterol without drugs -- if they don't mind sprinkling some flaxseed into their daily diet.

27 Mar 2010

NCMHD announces $3.8M grant for research on minority recruitment in cancer clinical trials

The University of Minnesota Medical School today announced the details of a $3.8 million grant by the National Institutes of Health's National Center on Minority Health and Health Disparities for research focused on minority recruitment and retention in cancer clinical trials.

26 Mar 2010

Treatment with beta-blockers can help reduce spread of cancer in patients with breast tumours

Treatment with beta-blockers can help reduce the spread of cancer in patients with breast tumours, a researcher will tell the seventh European Breast Cancer Conference in Barcelona today (Friday).

26 Mar 2010

UK government commits £250M for proposed medical research and innovation centre

Gordon Brown has announced the government's commitment to investing £250 million in the proposed UK Centre for Medical Research and Innovation (UKCMRI).

26 Mar 2010

Medical Research News

ER stress response is major driver of insulin resistance, say researchers

TB-causing bacteria can hijack fat metabolism to drive progression of the disease

New approach may circumvent lost response in insulin due to obesity

UCSF approach may one day be used to create new periods of plasticity in human brain

SAMHSA survey: Underage drinking rates reach more than 27.6% in the past month

New scientific discoveries show that Canadian maple syrup can be good for health

Study: Automatic reporting of estimated GFR may result in unnecessary referrals by physicians

Early stopping of clinical trials result in misleading estimates of treatment effects: Study

Young adults increasingly flocking to EDs for medical treatment

Study finds association between socioeconomic position and risk of death

Thermo Fisher Scientific, Eli Lilly expand clinical trial materials supply chain relationship

Ontario announces increase in budget for research and innovation, OBIO applauds

Depressed Latinos who stigmatize mental illness less likely to take medication: Study

Studies shed light on treatment options for women carrying BRCA1 and BRCA2 genetic mutations

ETSU wins $9.1M federal stimulus grant from NIH

Ford Motor donates $255,000 to fund completion of Oakwood Healthcare System's research study

New study may give men a way to combat high cholesterol without drugs

NCMHD announces $3.8M grant for research on minority recruitment in cancer clinical trials

Treatment with beta-blockers can help reduce spread of cancer in patients with breast tumours

UK government commits £250M for proposed medical research and innovation centre

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology

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