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Discovery of gene variant associated with increased risk of atopic dermatitis

Scientists of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch and Charité - University Medical School, Berlin, Germany, in collaboration with researchers from the Klinikum rechts der Isar of Technical University Munich and Christian Albrecht University, Kiel, have identified a gene variant on chromosome 11 that is associated with an increased risk of atopic dermatitis.

6 Apr 2009

New standardized tool for the assessment of chronic pain helps distinguish pain subtypes

Joachim Scholz from Massachusetts General Hospital in Boston, USA and his colleagues studied the symptoms and signs of patients with peripheral neuropathic pain (nerve pain such as sciatica) and non-neuropathic (non-nerve) low back pain to identify the best clinical questions and physical tests for diagnosing pain types.

6 Apr 2009

Pre-surgical stress management improves mood, quality of life

Brief stress management sessions prior to and immediately after surgery may have both short- and long-term benefit for men undergoing a radical prostatectomy for early-stage prostate cancer, according to research from The University of Texas M. D. Anderson Cancer Center.

6 Apr 2009

How the retina works: Like a multi-layered jigsaw puzzle of receptive fields

About 1.25 million neurons in the retina -- each of which views the world only through a small jagged window called a receptive field -- collectively form the seamless picture we rely on to navigate our environment.

6 Apr 2009

Researchers aim to determine if specific brain circuits and pathways might be responsible for wisdom

Researchers at the University of California, San Diego School of Medicine have compiled the first-ever review of the neurobiology of wisdom – once the sole province of religion and philosophy.

6 Apr 2009

Rak gene helps protect tumor suppressor in breast cancer

Scientists at The University of Texas M. D. Anderson Cancer Center have discovered a gene that protects PTEN, a major tumor-suppressor that is reduced but rarely mutated in about half of all breast cancers.

6 Apr 2009

Dietary flaxseed may help prevent colorectal tumors

New research from South Dakota State University offers evidence that including flax in the diet may help prevent colorectal tumors or keep tumors from growing as quickly when they do form.

6 Apr 2009

2,516 potential biomarkers of pancreatic cancer

A cancer scientist from Johns Hopkins has convinced an international group of colleagues to delay their race to find new cancer biomarkers and instead begin a 7,000-hour slog through a compendium of 50,000 scientific articles already published to assemble, decode and analyze the molecules that might herald the furtive presence of pancreatic cancer.

6 Apr 2009

Broccoli sprouts suppress Helicobacter pylori infections

Three-day-old broccoli sprouts, a widely available human food, suppressed Helicobacter pylori (H. pylori) infections, according to a report in Cancer Prevention Research, a journal of the American Association for Cancer Research. H. pylori infections are one of the most common bacterial infections worldwide and are a major cause of stomach cancer.

6 Apr 2009

AVEO Pharmaceuticals announces findings from novel human-in-mouse cancer model system

AVEO Pharmaceuticals, Inc. has announced findings from its novel human-in-mouse (HIM) cancer model system, in which AVEO successfully created invasive human tumors from primary human breast tissue that develop over time in mice and mimic human tumor behaviors and response.

6 Apr 2009

Biomarker associated with poor outcome in aggressive childhood cancer

Results from a new study identify a biomarker that may be useful for predicting the outcome of treatment for neuroblastoma, the most common cancer in young children.

6 Apr 2009

Niacin findings could open up new avenues for drug discovery

Deft molecular detective work at Duke University Medical Center suggests that scientists may soon be able to resurrect niacin as one of the best and cheapest ways to manage cholesterol.

6 Apr 2009

$New target for treatment of hormone refractory prostate cancer$

New target for treatment of hormone refractory prostate cancer

A new study identifies a protein that modifies the androgen receptor (AR) and influences its ability to regulate target genes linked with the progression of prostate cancer.

6 Apr 2009

Two non-pharmacological interventions reduce depression after heart surgery

Two non-pharmacological interventions-cognitive behavior therapy and supportive stress management-appear more effective than usual care for treating depression after coronary artery bypass surgery, according to a report in the April issue of Archives of General Psychiatry.

6 Apr 2009

BRAF gene mutation is a crucial skin cancer switch

Up to 70 per cent of melanoma skin cancers could be triggered by a particular genetic mutation, according to a Cancer Research UK funded study published in Cancer Cell.

6 Apr 2009

Moderate kidney disease associated with cardiovascular events

Chronic kidney disease patients face a greater risk of cardiovascular events such as stent thrombosis after being treated for heart attacks, even if their kidney disease is moderate, according to researchers from Wake Forest University Baptist Medical Center.

6 Apr 2009

Researchers at the UJI increase the efficiency of photocatalysts used in cancer treatments

Researchers at the Universitat Jaume I (UJI) in Castellon have found porous polymeric materials that increase the efficiency of traditional photocatalysts in the treatment of cancer.

6 Apr 2009

Stem cell innovation at risk

Despite great hopes for stem cell therapy, major structural and cultural changes within the NHS are needed if it is to succeed in the UK. Currently the chances of getting effective treatments into routine use in the short-term are small and the industry is at serious risk of 'market failure'.

6 Apr 2009

Play - a prescription for autism!

According to an American autism expert, many autistic children, with the right teaching, can overcome many of the disorder's difficult characteristics.

6 Apr 2009